Perirenal hematoma in a patient treated with bevacizumab for metastatic colon cancer: A case report

Lee,Min  Sung; Shin,Il  Sang; Kwun,Do  Hyung; Kim,Se  Hyung; Kim,Hyun  Jung; Kim,Chan  Kyu; Park,Seong  Kyu; Hong,Dae  Sik; Yun,Jina

doi:10.3892/ol.2016.4328

May-2016 Volume 11 Issue 5

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May-2016 Volume 11 Issue 5

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Case Report

Perirenal hematoma in a patient treated with bevacizumab for metastatic colon cancer: A case report

Authors:
- Min Sung Lee
- Il Sang Shin
- Do Hyung Kwun
- Se Hyung Kim
- Hyun Jung Kim
- Chan Kyu Kim
- Seong Kyu Park
- Dae Sik Hong
- Jina Yun
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Affiliations: Division of Hematology‑Oncology, Department of Internal Medicine, Soonchunhyang University School of Medicine, Bucheon Hospital, Bucheon, Gyeonggi 420‑767, Republic of Korea
Pages: 3210-3212
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Published online on: March 11, 2016

https://doi.org/10.3892/ol.2016.4328
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Abstract

The present study reports the case of a patient that developed spontaneous perirenal hematoma during treatment with bevacizumab-containing chemotherapy. A 44-year-old woman with metastatic sigmoid colon cancer, who was being treated with bevacizumab (5 mg/kg, intravenous, 90 min biweekly), was admitted to hospital following 3 cycles of chemotherapy, with a sudden onset of dyspnea and oliguria. An emergency hemodialysis was performed and a large right perirenal hematoma was diagnosed using computed tomography. The patient was immediately instructed to discontinue chemotherapy, including bevacizumab. However, the right perirenal hematoma increased in size and a left perirenal hematoma developed 3 weeks later. The two perirenal hematomas stabilized 7 weeks subsequent to the termination of bevacizumab treatment. Spontaneous perirenal hematoma due to bevacizumab treatment is an extremely rare occurrence. However, physicians should be aware of this potential complication associated with bevacizumab treatment.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Perirenal hematoma in a patient treated with bevacizumab for metastatic colon cancer: A case report

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