Esophageal cancer diagnosed by high-resolution manometry of the esophagus: A case report

Liu,Rongbei; Chu,Hua; Xu,Fei; Chen,Shujie

doi:10.3892/ol.2016.4332

May-2016 Volume 11 Issue 5

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May-2016 Volume 11 Issue 5

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Case Report

Esophageal cancer diagnosed by high-resolution manometry of the esophagus: A case report

Authors:
- Rongbei Liu
- Hua Chu
- Fei Xu
- Shujie Chen
View Affiliations / Copyright

Affiliations: Department of Gastroenterology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310000, P.R. China
Pages: 3131-3134
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Published online on: March 16, 2016

https://doi.org/10.3892/ol.2016.4332
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Abstract

A 48-year-old female who presented with a history of dysphagia for 5 months and regurgitation for 1 week was referred to the Sir Run Run Shaw Hospital (Hangzhou, China) for further evaluation, since the gastroscopy and endoscopic ultrasound performed in local hospitals did not reveal the presence of cancer. High‑resolution manometry (HRM) of the esophagus was performed to determine the patient's condition, and revealed an abnormal high‑pressure zone that was located 33 cm from the incisor and did not relax upon swallowing. Synchronous waves were observed, and the pressure of the esophageal lumen was found to increase with secondary synchronous peristaltic waves. The lower esophageal sphincter was 39 cm from the incisor and relaxed upon swallowing. The abnormal high‑pressure zone could have been caused by an obstruction, and therefore an upper gastrointestinal series (barium swallow) test and gastroscopy were recommended to further pinpoint the cause. Following the two examinations, mid‑esophageal cancer was considered as a possible diagnosis. A biopsy was performed and the final diagnosis was that of basaloid squamous cell carcinoma. The findings of the present study suggest that, for patients with evident symptoms of esophageal motor dysfunction without significant gastroscopy findings, HRM is recommended.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Esophageal cancer diagnosed by high-resolution manometry of the esophagus: A case report

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