Association between intraosseous schwannoma occurrence and the position of the intraosseous nutrient vessel: A case report

Suzuki,Kayo; Yasuda,Taketoshi; Watanabe,Kenta; Kanamori,Masahiko; Kimura,Tomoatsu

doi:10.3892/ol.2016.4363

May-2016 Volume 11 Issue 5

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May-2016 Volume 11 Issue 5

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Case Report

Association between intraosseous schwannoma occurrence and the position of the intraosseous nutrient vessel: A case report

Authors:
- Kayo Suzuki
- Taketoshi Yasuda
- Kenta Watanabe
- Masahiko Kanamori
- Tomoatsu Kimura
View Affiliations / Copyright

Affiliations: Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama 930‑0194, Japan, Department of Human Science 1, Faculty of Medicine, University of Toyama, Toyama 930‑0194, Japan
Pages: 3185-3188
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Published online on: March 22, 2016

https://doi.org/10.3892/ol.2016.4363
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Abstract

Intraosseous schwannoma is a rare benign bone tumor that originates from Schwann cells of the nerve sheath. The majority of intraosseous schwannomas arise in the mandible and sacrum, but an intraosseous schwannoma involving the ulna is described in the present case report. Radiologically, the current case presented as a well‑defined lytic lesion, with a pathological fracture and no intralesional calcification, in the proximal metaphysis of the left ulna. Using magnetic resonance imaging, an intraosseous mass spreading out from the cortical defect was observed. The lesion appeared isointense to skeletal muscle on T1‑weighted images, and hyperintense or heterogeneous on T2‑weighted images. The differential diagnosis comprised benign bone tumors, including bone cyst, aneurysmal bone cyst, giant cell tumor and fibrous dysplasia. Based on the results of a needle biopsy, a schwannoma involving the ulnar bone was diagnosed, and tumor marginal resection followed by artificial bone grafting and fixation was performed. A total of one year subsequent to surgery, the patient exhibits no symptoms, and there is no evidence of disease recurrence.

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1	Antonescu CR, Perry A and Woodruff JM: Schwannoma (including variants). WHO Classification of Tumours of Soft Tissue and Bone. Fletcher CDM, Bridge JA, Hogendoorn P and Mertens F: 5:(4th). IARC Press. (Lyon). 170–172. 2013.
2	Unni KK and Inwards CY: Miscellaneous unusual tumors of bone. Dahlin's Bone Tumors: General Aspects and Data on 10,165 Cases (6th). Lippincott. (Williams & Wilkins, Philadelphia, PA). 295–298. 2010.
3	de la Monte SM, Dorfman HD, Chandra R and Malawer M: Intraosseous schwannoma: Histologic features, ultrastructure, and review of the literature. Hum Pathol. 15:551–558. 1984. View Article : Google Scholar : PubMed/NCBI
4	Ida CM, Scheithauer BW, Yapicier O, Carney JA, Wenger DE, Inwards CY, Bertoni F, Spinner RJ and Unni KK: Primary schwannoma of the bone: A clinicopathologic and radiologic study of 17 cases. Am J Surg Pathol. 35:989–997. 2011. View Article : Google Scholar : PubMed/NCBI
5	Aoki J, Tanikawa H, Fujioka F, Ishii K, Seo GS, Karakida O and Sone S: Intraosseous neurilemmoma of the fibula. Skeletal Radiol. 26:60–63. 1997. View Article : Google Scholar : PubMed/NCBI
6	Palocaren T, Walter NM, Madhuri V and Gibikote S: Schwannoma of the fibula. J Bone Joint Surg Br. 90:803–805. 2008. View Article : Google Scholar : PubMed/NCBI
7	Giné J, Calmet J, Sirvent JJ and Domènech S: Intraosseous neurilemmoma of the radius: A case report. J Hand Surg Am. 25:365–369. 2000. View Article : Google Scholar : PubMed/NCBI
8	Mutema GK and Sorger J: Intraosseous schwannoma of the humerus. Skeletal Radiol. 31:419–421. 2002. View Article : Google Scholar : PubMed/NCBI
9	Stull MA, Moser RP Jr, Kransdorf MJ, Bogumill GP and Nelson MC: Magnetic resonance appearance of peripheral nerve sheath tumors. Skeletal Radiol. 20:9–14. 1991. View Article : Google Scholar : PubMed/NCBI
10	Wirth WA and Bray CB Jr: Intra-osseous neurilemmoma. Case report and review of thirty-one cases from the literature. J Bone Joint Surg Am. 59:252–255. 1977.PubMed/NCBI
11	Gordon EJ: Solitary intraosseous neurilemmoma of the tibia: Review of intraosseous neurilemmoma and neurofibroma. Clin Orthop Relat Res. 117:271–282. 1976.PubMed/NCBI
12	Zhang L, Xia BQ, Sun H, Wang LZ, Zhao ZL, Li B and Wang XD: Intraosseous schwannomas of the jaws: 2 case reports and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol. 114:e13–e17. 2012. View Article : Google Scholar : PubMed/NCBI
13	Turk PS, Peters N, Libbey NP and Wanebo HJ: Diagnosis and management of giant intrasacral schwannoma. Cancer. 70:2650–2657. 1992. View Article : Google Scholar : PubMed/NCBI
14	Unni KK, Inwards CY, Bridge JA, Kindblom LG and Wold LE: Miscellaneous tumors. AFIP Atals of Tumor Pathology Series IV: Tumors of the Bones and Joints (1st). 2:ARP Press. (Washington DC). 309–319. 2005.
15	Sherman MS: The nerves of bone. J Bone Joint Surg Am. 45:522–528. 1963.
16	Beris AE, Lykissas MG, Korompilias AV, Vekris MD, Mitsionis GI, Malizos KN and Soucacos PN: Vascularized fibula transfer for lower limb reconstruction. Microsurgery. 31:205–211. 2011. View Article : Google Scholar : PubMed/NCBI
17	Matsuura M, Ohno K, Michi K, Egawa K and Takiguchi R: Clinicoanatomic examination of the fibula: Anatomic basis for dental implant placement. Int J Oral Maxillofac Implants. 14:879–884. 1999.PubMed/NCBI
18	Sheetz KK, Bishop AT and Berger RA: The arterial blood supply of the distal radius and ulna and its potential use in vascularized pedicled bone grafts. J Hand Surg Am. 20:902–914. 1995. View Article : Google Scholar : PubMed/NCBI
19	Kimball JP, Glowczewskie F and Wright TW: Intraosseous blood supply to the distal humerus. J Hand Surg Am. 32:642–646. 2007. View Article : Google Scholar : PubMed/NCBI
20	Hardy BT, Glowczewskie F Jr and Wright TW: Vascular anatomy of the proximal ulna. J Hand Surg Am. 36:808–810. 2011. View Article : Google Scholar : PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Association between intraosseous schwannoma occurrence and the position of the intraosseous nutrient vessel: A case report

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