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Case Report

Primary diffuse large B-cell lymphoma of the central nervous system: A case report and literature review

  • Authors:
    • Dawei Chen
    • Weihong Gu
    • Wenzhong Li
    • Xiaoliang Liu
    • Xiaoyu Yang
  • View Affiliations / Copyright

    Affiliations: Department of Neurosurgery, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China, Department of Surgery, The Second Hospital of Jilin University, Changchun, Jilin 130021, P.R. China
  • Pages: 3085-3090
    |
    Published online on: March 22, 2016
       https://doi.org/10.3892/ol.2016.4365
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Abstract

The present study reports the clinical diagnosis and management of a patient with primary diffuse large B-cell lymphoma (Bcl) of the central nervous system (CNS). Making an early diagnosis of primary diffuse large Bcl is challenging due to the variable and complicated clinical manifestations of the disease. The relevant literature was reviewed, and high‑dose methotrexate, whole brain radiotherapy and highly active antiretroviral therapy was recommended for the patient. The present study elucidates the role of positron emission tomography‑computed tomography scans for the diagnosis and management of primary diffuse large Bcl of the CNS, and demonstrates the importance of resection surgery in the management of the disease. Specifically, the present study proposes that resection surgery may be applied in the early stages of disease for patients with a single occupied lesion and increased intracranial pressure.
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Copy and paste a formatted citation
Spandidos Publications style
Chen D, Gu W, Li W, Liu X and Yang X: Primary diffuse large B-cell lymphoma of the central nervous system: A case report and literature review. Oncol Lett 11: 3085-3090, 2016.
APA
Chen, D., Gu, W., Li, W., Liu, X., & Yang, X. (2016). Primary diffuse large B-cell lymphoma of the central nervous system: A case report and literature review. Oncology Letters, 11, 3085-3090. https://doi.org/10.3892/ol.2016.4365
MLA
Chen, D., Gu, W., Li, W., Liu, X., Yang, X."Primary diffuse large B-cell lymphoma of the central nervous system: A case report and literature review". Oncology Letters 11.5 (2016): 3085-3090.
Chicago
Chen, D., Gu, W., Li, W., Liu, X., Yang, X."Primary diffuse large B-cell lymphoma of the central nervous system: A case report and literature review". Oncology Letters 11, no. 5 (2016): 3085-3090. https://doi.org/10.3892/ol.2016.4365
Copy and paste a formatted citation
x
Spandidos Publications style
Chen D, Gu W, Li W, Liu X and Yang X: Primary diffuse large B-cell lymphoma of the central nervous system: A case report and literature review. Oncol Lett 11: 3085-3090, 2016.
APA
Chen, D., Gu, W., Li, W., Liu, X., & Yang, X. (2016). Primary diffuse large B-cell lymphoma of the central nervous system: A case report and literature review. Oncology Letters, 11, 3085-3090. https://doi.org/10.3892/ol.2016.4365
MLA
Chen, D., Gu, W., Li, W., Liu, X., Yang, X."Primary diffuse large B-cell lymphoma of the central nervous system: A case report and literature review". Oncology Letters 11.5 (2016): 3085-3090.
Chicago
Chen, D., Gu, W., Li, W., Liu, X., Yang, X."Primary diffuse large B-cell lymphoma of the central nervous system: A case report and literature review". Oncology Letters 11, no. 5 (2016): 3085-3090. https://doi.org/10.3892/ol.2016.4365
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