Malignant transformation of an epidermoid cyst in the temporal and prepontine region: Report of a case and differential diagnosis

Ding,Shenghao; Jin,Yichao; Jiang,Jiyao

doi:10.3892/ol.2016.4368

May-2016 Volume 11 Issue 5

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May-2016 Volume 11 Issue 5

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Article

Malignant transformation of an epidermoid cyst in the temporal and prepontine region: Report of a case and differential diagnosis

Authors:
- Shenghao Ding
- Yichao Jin
- Jiyao Jiang
View Affiliations / Copyright

Affiliations: Department of Neurosurgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, P.R. China
Pages: 3097-3100
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Published online on: March 22, 2016

https://doi.org/10.3892/ol.2016.4368
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Abstract

Malignant transformation of an epidermoid cyst is rare. The current report presents a case of a 55-year-old female patient with squamous cell carcinoma arising from a benign epidermoid cyst in the left temporal region and prepontine area. She had undergone subtotal resection of an epidermoid cyst 7 months previously. Preoperative imaging findings included a focal enhancing area adjacent to the lesion. Postoperative computed tomography demonstrated an increase in the size of the enhancing area. The patient underwent removal of the lesion and postoperative histological examination revealed a squamous cell carcinoma possibly arising from the epidermoid cyst. Accurate diagnosis of malignant transformation prior to operation is difficult; however, the possibility of an intracranial epidermoid cyst must be considered if a focally enhancing area is visible. Postoperative histological examinations may be used to determine a definite diagnosis, and accurate diagnosis is important for planning a rational therapeutic strategy.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Malignant transformation of an epidermoid cyst in the temporal and prepontine region: Report of a case and differential diagnosis

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