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Case Report

Fever and arthralgia as the initial symptoms of primary bone marrow diffuse large B-cell lymphoma: A case report

  • Authors:
    • Saisai Ren
    • Yanling Tao
    • Lu Jia
    • Panpan Cheng
    • Jilei Zhang
    • Hao Zhang
  • View Affiliations / Copyright

    Affiliations: Graduate School, Jining Medical University, Jining, Shandong 272000, P.R. China, Department of Pediatrics, Affiliated Hospital of Jining Medical University, Jining, Shandong 272129, P.R. China, Department of Hematology, Affiliated Hospital of Jining Medical University, Jining, Shandong 272129, P.R. China
  • Pages: 3428-3432
    |
    Published online on: April 4, 2016
       https://doi.org/10.3892/ol.2016.4405
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Abstract

Primary bone marrow diffuse large B-cell lymphoma (DLBCL) is rare, and only a few cases have been reported. Fever and arthralgia as the initial symptom are extremely rare; however, awareness must be made of this presentation. The current study describes the clinical and pathological findings of a 41‑year‑old man affected by fever and arthralgia. Blood tests revealed leukopenia and anemia. Multiple bone marrow biopsies were conducted and confirmed the diagnosis of primary bone marrow DLBCL. Primary bone marrow DLBCL is a rare and frequently misdiagnosed subset of non‑Hodgkin's lymphoma. The current case demonstrates that utility of bone marrow biopsy for diagnosis should not be ignored, and that repeated bone marrow punctures in multiple locations may be necessary.
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Copy and paste a formatted citation
Spandidos Publications style
Ren S, Tao Y, Jia L, Cheng P, Zhang J and Zhang H: Fever and arthralgia as the initial symptoms of primary bone marrow diffuse large B-cell lymphoma: A case report. Oncol Lett 11: 3428-3432, 2016.
APA
Ren, S., Tao, Y., Jia, L., Cheng, P., Zhang, J., & Zhang, H. (2016). Fever and arthralgia as the initial symptoms of primary bone marrow diffuse large B-cell lymphoma: A case report. Oncology Letters, 11, 3428-3432. https://doi.org/10.3892/ol.2016.4405
MLA
Ren, S., Tao, Y., Jia, L., Cheng, P., Zhang, J., Zhang, H."Fever and arthralgia as the initial symptoms of primary bone marrow diffuse large B-cell lymphoma: A case report". Oncology Letters 11.5 (2016): 3428-3432.
Chicago
Ren, S., Tao, Y., Jia, L., Cheng, P., Zhang, J., Zhang, H."Fever and arthralgia as the initial symptoms of primary bone marrow diffuse large B-cell lymphoma: A case report". Oncology Letters 11, no. 5 (2016): 3428-3432. https://doi.org/10.3892/ol.2016.4405
Copy and paste a formatted citation
x
Spandidos Publications style
Ren S, Tao Y, Jia L, Cheng P, Zhang J and Zhang H: Fever and arthralgia as the initial symptoms of primary bone marrow diffuse large B-cell lymphoma: A case report. Oncol Lett 11: 3428-3432, 2016.
APA
Ren, S., Tao, Y., Jia, L., Cheng, P., Zhang, J., & Zhang, H. (2016). Fever and arthralgia as the initial symptoms of primary bone marrow diffuse large B-cell lymphoma: A case report. Oncology Letters, 11, 3428-3432. https://doi.org/10.3892/ol.2016.4405
MLA
Ren, S., Tao, Y., Jia, L., Cheng, P., Zhang, J., Zhang, H."Fever and arthralgia as the initial symptoms of primary bone marrow diffuse large B-cell lymphoma: A case report". Oncology Letters 11.5 (2016): 3428-3432.
Chicago
Ren, S., Tao, Y., Jia, L., Cheng, P., Zhang, J., Zhang, H."Fever and arthralgia as the initial symptoms of primary bone marrow diffuse large B-cell lymphoma: A case report". Oncology Letters 11, no. 5 (2016): 3428-3432. https://doi.org/10.3892/ol.2016.4405
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