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Case Report Open Access

Coexisting and possible primary extra-gastrointestinal stromal tumors of the pancreas and liver: A single case report

  • Authors:
    • Lei Liu
    • Yingqiao Zhu
    • Dongxuan Wang
    • Changbin Yang
    • Qi Zhang
    • Xiukun Li
    • Yang Bai
  • View Affiliations / Copyright

    Affiliations: Department of Ultrasound, First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China, Department of Radiation Oncology, The Tumor Hospital of Jilin Province, Changchun, Jilin 130012, P.R. China , Department of Ultrasound, College of Pharmacy, Jilin University, Changchun, Jilin 130012, P.R. China, Ultrasound Department, Jilin Provincial People's Hospital, Changchun, Jilin 130021, P.R. China
    Copyright: © Liu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 3303-3307
    |
    Published online on: April 7, 2016
       https://doi.org/10.3892/ol.2016.4420
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Abstract

Gastrointestinal stromal tumors (GIST) are mesenchymal neoplasms of the gastrointestinal tract (GI) that are defined, in part, by the expression of CD117, a c-Kit proto-oncogene protein. GISTs emerge outside of the GI at a very low frequency, typically in a single organ or location. GISTs that occasionally emerge outside of the GI are classified as extra-gastrointestinal stromal tumors (EGIST). The present study reports an extremely rare case of EGIST detected in the pancreas and the liver. The pancreatic and liver tumors were 4.5x2.5 cm and 2.0x1.5 cm in size, respectively. Both tumors consisted of CD117‑positive spindle cells with a similar mitotic rate of 1‑2 per 50 high power fields. The pancreatic and the hepatic EGISTs were at a low risk of malignancy, and both tumors were proposed to be primary stromal tumors. To the best of our knowledge, this is the first report of likely primary EGIST identified in the pancreas and liver of the same patient.
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Copy and paste a formatted citation
Spandidos Publications style
Liu L, Zhu Y, Wang D, Yang C, Zhang Q, Li X and Bai Y: Coexisting and possible primary extra-gastrointestinal stromal tumors of the pancreas and liver: A single case report. Oncol Lett 11: 3303-3307, 2016.
APA
Liu, L., Zhu, Y., Wang, D., Yang, C., Zhang, Q., Li, X., & Bai, Y. (2016). Coexisting and possible primary extra-gastrointestinal stromal tumors of the pancreas and liver: A single case report. Oncology Letters, 11, 3303-3307. https://doi.org/10.3892/ol.2016.4420
MLA
Liu, L., Zhu, Y., Wang, D., Yang, C., Zhang, Q., Li, X., Bai, Y."Coexisting and possible primary extra-gastrointestinal stromal tumors of the pancreas and liver: A single case report". Oncology Letters 11.5 (2016): 3303-3307.
Chicago
Liu, L., Zhu, Y., Wang, D., Yang, C., Zhang, Q., Li, X., Bai, Y."Coexisting and possible primary extra-gastrointestinal stromal tumors of the pancreas and liver: A single case report". Oncology Letters 11, no. 5 (2016): 3303-3307. https://doi.org/10.3892/ol.2016.4420
Copy and paste a formatted citation
x
Spandidos Publications style
Liu L, Zhu Y, Wang D, Yang C, Zhang Q, Li X and Bai Y: Coexisting and possible primary extra-gastrointestinal stromal tumors of the pancreas and liver: A single case report. Oncol Lett 11: 3303-3307, 2016.
APA
Liu, L., Zhu, Y., Wang, D., Yang, C., Zhang, Q., Li, X., & Bai, Y. (2016). Coexisting and possible primary extra-gastrointestinal stromal tumors of the pancreas and liver: A single case report. Oncology Letters, 11, 3303-3307. https://doi.org/10.3892/ol.2016.4420
MLA
Liu, L., Zhu, Y., Wang, D., Yang, C., Zhang, Q., Li, X., Bai, Y."Coexisting and possible primary extra-gastrointestinal stromal tumors of the pancreas and liver: A single case report". Oncology Letters 11.5 (2016): 3303-3307.
Chicago
Liu, L., Zhu, Y., Wang, D., Yang, C., Zhang, Q., Li, X., Bai, Y."Coexisting and possible primary extra-gastrointestinal stromal tumors of the pancreas and liver: A single case report". Oncology Letters 11, no. 5 (2016): 3303-3307. https://doi.org/10.3892/ol.2016.4420
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