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Intra-abdominal desmoplastic small round cell tumors: CT and FDG-PET/CT findings with histopathological association

  • Authors:
    • Jingjing Chen
    • Zengjie Wu
    • Binbin Sun
    • Dacheng Li
    • Zhenguang Wang
    • Fangjun Liu
    • Hui Hua
  • View Affiliations / Copyright

    Affiliations: Department of Radiology, The Affiliated Hospital of Qingdao University, Shandong 266003, P.R. China, Department of Positron Emission Tomography/Computed Tomography, Qingdao Center Medical Group, Shandong 266042, P.R. China, Department of Diagnostic Ultrasound, Affiliated Zhucheng People's Hospital, Weifang Medical University, Shandong 262200, P.R. China, Department of Positron Emission Tomography/Computed Tomography, The Affiliated Hospital of Qingdao University, Shandong 266003, P.R. China, Institute of Plastic Surgery, Weifang Medical University, Shandong 261042, P.R. China, Department of Otorhinolaryngology ‑ Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Shandong 266003, P.R. China
    Copyright: © Chen et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 3298-3302
    |
    Published online on: April 7, 2016
       https://doi.org/10.3892/ol.2016.4421
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Abstract

Desmoplastic small round cell tumors (DSRCTs) are rare and aggressive malignant tumors. The aim of the present study was to analyze computed tomography (CT) and fluorodeoxyglucose positron emission tomography (FDG-PET)/CT imaging features of intra-abdominal desmoplastic DSRCT, and investigate the association of these features with histopathological results. The present study was a retrospective investigation of 4 patients with DSRCT. All patients underwent CT and dynamic CT, and 1 additionally underwent FDG‑PET/CT scanning. Following a tumor resection, routine hematoxylin and eosin staining, and immunostaining, were performed and evaluated. Multiple large abdominopelvic masses were identified in all 4 patients; however, no indications of their site of origin were demonstrated. CT revealed soft-tissue masses with patchy foci of hypodense lesions. Contrast-enhanced CT revealed slightly or moderately heterogeneous enhancement of the lesions. Other observations from these patients included calcification (n=2), peritoneal seeding (n=3), hepatic metastasis (n=3), retroperitoneal lymphadenopathy (n=3) and ascites (n=2). FDG‑PET/CT revealed multiple nodular increased FDG uptake in the abdominopelvic masses, and in the liver and peritoneum in 1 case. Intra‑abdominal DSRCT demonstrated significant diagnostic characteristics on plain and contrast‑enhanced CT. Multiple, bulky soft‑tissue masses inside the peritoneal cavity, particularly in male adolescents and young adults, should be considered as potential cases of DSRCT. FDG-PET/CT techniques may be utilized to aid the staging of tumors.
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Copy and paste a formatted citation
Spandidos Publications style
Chen J, Wu Z, Sun B, Li D, Wang Z, Liu F and Hua H: Intra-abdominal desmoplastic small round cell tumors: CT and FDG-PET/CT findings with histopathological association. Oncol Lett 11: 3298-3302, 2016.
APA
Chen, J., Wu, Z., Sun, B., Li, D., Wang, Z., Liu, F., & Hua, H. (2016). Intra-abdominal desmoplastic small round cell tumors: CT and FDG-PET/CT findings with histopathological association. Oncology Letters, 11, 3298-3302. https://doi.org/10.3892/ol.2016.4421
MLA
Chen, J., Wu, Z., Sun, B., Li, D., Wang, Z., Liu, F., Hua, H."Intra-abdominal desmoplastic small round cell tumors: CT and FDG-PET/CT findings with histopathological association". Oncology Letters 11.5 (2016): 3298-3302.
Chicago
Chen, J., Wu, Z., Sun, B., Li, D., Wang, Z., Liu, F., Hua, H."Intra-abdominal desmoplastic small round cell tumors: CT and FDG-PET/CT findings with histopathological association". Oncology Letters 11, no. 5 (2016): 3298-3302. https://doi.org/10.3892/ol.2016.4421
Copy and paste a formatted citation
x
Spandidos Publications style
Chen J, Wu Z, Sun B, Li D, Wang Z, Liu F and Hua H: Intra-abdominal desmoplastic small round cell tumors: CT and FDG-PET/CT findings with histopathological association. Oncol Lett 11: 3298-3302, 2016.
APA
Chen, J., Wu, Z., Sun, B., Li, D., Wang, Z., Liu, F., & Hua, H. (2016). Intra-abdominal desmoplastic small round cell tumors: CT and FDG-PET/CT findings with histopathological association. Oncology Letters, 11, 3298-3302. https://doi.org/10.3892/ol.2016.4421
MLA
Chen, J., Wu, Z., Sun, B., Li, D., Wang, Z., Liu, F., Hua, H."Intra-abdominal desmoplastic small round cell tumors: CT and FDG-PET/CT findings with histopathological association". Oncology Letters 11.5 (2016): 3298-3302.
Chicago
Chen, J., Wu, Z., Sun, B., Li, D., Wang, Z., Liu, F., Hua, H."Intra-abdominal desmoplastic small round cell tumors: CT and FDG-PET/CT findings with histopathological association". Oncology Letters 11, no. 5 (2016): 3298-3302. https://doi.org/10.3892/ol.2016.4421
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