Misdiagnosis of primary pleomorphic rhabdomyosarcoma of the right thigh in a young adult: A case report

Yu,Xiaolong; Yang,Yong; Zhang,Bin; Liu,Hucheng; Guo,Runsheng; Dai,Min

doi:10.3892/ol.2016.4819

Misdiagnosis of primary pleomorphic rhabdomyosarcoma of the right thigh in a young adult: A case report

Authors:
- Xiaolong Yu
- Yong Yang
- Bin Zhang
- Hucheng Liu
- Runsheng Guo
- Min Dai
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Affiliations: Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, Nanchang, Jiangxi 330006, P.R. China, Department of Orthopedics, Xinyu People's Hospital, Xinyu, Jiangxi 338025, P.R. China, Multidisciplinary Therapy Center of Musculoskeletal Tumor, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China
Published online on: July 7, 2016 https://doi.org/10.3892/ol.2016.4819
Pages: 1921-1924

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Abstract

Pleomorphic rhabdomyosarcoma (PRMS) is a rare type of soft tissue tumor accounting for <2% of all adult sarcomas. The present study describes a case of a 28‑year‑old male patient with primary PRMS of the right thigh. The patient was initially diagnosed with a schwannoma and underwent conservative therapy at a local hospital. At the 6-month follow-up, the patient reported a marked increase in the size of the mass. Finally, the patient underwent fine‑needle aspiration and total tumor resection. The tumor measured 11x9x5 cm³ in size and was located in the vastus intermedius muscle. According to histological and immunohistochemical findings, a diagnosis of PRMS was confirmed by an expert pathology consultant. Postoperative follow-up at 3 months revealed no evidence of recurrent disease or residual side effects from therapy. However, it is imperative that such cases are closely monitored following surgery, in order to evaluate the long‑term efficacy of the procedure, since misdiagnosis may increase the risk of recurrence and metastasis. The present case is noteworthy due to the misdiagnosis of PRMS, the large size of the mass and the young age of the patient.

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