Atypical presentation of a gastric stromal tumor masquerading as a giant intraabdominal cyst: A case report

Sun,Ke‑Kang; Xu,Song; Chen,Jinzhen; Liu,Gang; Shen,Xiaojun; Wu,Xiaoyang

doi:10.3892/ol.2016.4968

Atypical presentation of a gastric stromal tumor masquerading as a giant intraabdominal cyst: A case report

Authors:
- Ke‑Kang Sun
- Song Xu
- Jinzhen Chen
- Gang Liu
- Xiaojun Shen
- Xiaoyang Wu
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Affiliations: Department of Gastrointestinal Surgery, Kunshan First People's Hospital Affiliated to Jiangsu University, Kunshan, Jiangsu 215300, P.R. China, Department of Pathology, Kunshan First People's Hospital Affiliated to Jiangsu University, Kunshan, Jiangsu 215300, P.R. China
Published online on: August 8, 2016 https://doi.org/10.3892/ol.2016.4968
Pages: 3018-3020

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Abstract

Gastrointestinal stromal tumors (GISTs) are mesenchymal neoplasms that arise in the gastrointestinal tract, accounting for ~1% of gastric malignancies. The present study reports the case of a GIST of the stomach in a 75‑year‑old man who presented with abdominal distension and anorexia for 1 month. Gastroscopy was unremarkable. Ultrasound and computed tomography (CT) scans showed a giant intraabdominal cystic lesion of unknown origin. The lesion was initially believed to be a duplication cyst, a pancreatic pseudocyst or a liver cyst in the pre‑operative diagnosis. Exploratory laparotomy revealed a cystic lesion of the lesser sac originating from the lesser curvature of the stomach. A distal gastrectomy with en bloc resection of the lesion was performed. The intraoperative frozen section showed a spindle‑cell GIST and microscopically negative margins. The patient was treated with imatinib for 1 year. The latest CT scan at 14 months post‑surgery did not show any recurrence. Although GISTs presenting as predominantly cystic lesions are very rare, they should be considered in the differential diagnosis of cystic lesions of the upper abdomen.

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1	Joensuu H, Hohenberger P and Corless CL: Gastrointestinal stromal tumor. Lancet. 382:973–983. 2013. View Article : Google Scholar : PubMed/NCBI
2	Nilsson B, Bümming P, Meis-Kindblom JM, Odén A, Dortok A, Gustavsson B, Sablinska K and Kindblom LG: Gastrointestinal stromal tumors: The incidence, prevalence, clinical course, and prognostication in the preimatinib mesylate era - a population-based study in western Sweden. Cancer. 103:821–829. 2005. View Article : Google Scholar : PubMed/NCBI
3	Samelis GF, Ekmektzoglou KA and Zografos GC: Gastrointestinal stromal tumours: Clinical overview, surgery and recent advances in imatinib mesylate therapy. Eur J Surg Oncol. 33:942–950. 2007. View Article : Google Scholar : PubMed/NCBI
4	Abdel-Monem S, Enaba MM, Hassan TA, et al: Multislice CT imaging of gastrointestinal stromal tumors (GISTs). Egypt J Radiol Nuc Med. 42:1–7. 2011. View Article : Google Scholar
5	Kumar A, Jakhmola CK, Chauhan SS and Singh A: A typical presentation of gastrointestinal stromal tumor masquerading as a large duodenal cyst: A case report. Int J Surg Case Rep. 9:123–126. 2015. View Article : Google Scholar : PubMed/NCBI
6	Cavallaro G, Sadighi A, Polistena A, Rossi V, Cristaldi M, Paparelli C and De Toma G: Pedunculated giant GISTs of the stomach with exophytic growth: Report of two cases. Int J Surg. 6:e80–e82. 2008. View Article : Google Scholar : PubMed/NCBI
7	Joensuu H, Vehtari A, Riihimäki J, Nishida T, Steigen SE, Brabec P, Plank L, Nilsson B, Cirilli C, Braconi C, et al: Risk of recurrence of gastrointestinal stromal tumour after surgery: An analysis of pooled population-based cohorts. Lancet Oncol. 13:265–274. 2012. View Article : Google Scholar : PubMed/NCBI
8	Choi BI, Kim YH and Han JK: Hepatobiliary and pancreatic: Cystic liver lesion in a man with abdominal pain. J Gastroenterol Hepatol. 14:609–613. 1999.PubMed/NCBI
9	Goettsch WG, Bos SD, Breekveldt-Postma N, Casparie M, Herings RM and Hogendoorn PC: Incidence of gastrointestinal stromal tumours is underestimated: Results of a nation-wide study. Eur J Cancer. 41:2868–2872. 2005. View Article : Google Scholar : PubMed/NCBI
10	Bucher P, Egger JF, Gervaz P, Ris F, Weintraub D, Villiger P, Buhler LH and Morel P: An audit of surgical management of gastrointestinal stromal tumours (GIST). Eur J Surg Oncol. 32:310–314. 2006. View Article : Google Scholar : PubMed/NCBI
11	Shaikh ST, Upwanshi MH, Shetty TS, Ghetla SR and Gheewala H: A Large Cystic Variant of Gastro-intestinal Stromal Tumour arising from the Jejunum: A Case Report. J Clin Diagn Res. 9:11–12. 2015.
12	Al-Thani H, El-Menyar A, Rasul KI, Al-Sulaiti M, El-Mabrok J, Hajaji K, Elgohary H and Tabeb A: Clinical presentation, management and outcomes of gastrointestinal stromal tumors. Int J Surg. 12:1127–1133. 2014. View Article : Google Scholar : PubMed/NCBI
13	Ricci R, Chiarello G, Attili F, Fuccio L, Alfieri S, Persiani R, Di Pietro S, Martini M, Costamagna G, Larocca LM and Larghi A: Endoscopic ultrasound-guided fine needle tissue acquisition biopsy samples do not allow a reliable proliferation assessment of gastrointestinal stromal tumours. Dig Liver Dis. 47:291–295. 2015. View Article : Google Scholar : PubMed/NCBI