Rapid increase in cystic volume of an anaplastic astrocytoma misdiagnosed as neurocysticercosis: A case report

Li,Hong‑Jiang; Han,Hong‑Xiu; Feng,Dong‑Fu

doi:10.3892/ol.2016.4986

October-2016 Volume 12 Issue 4

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October-2016 Volume 12 Issue 4

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Case Report

Rapid increase in cystic volume of an anaplastic astrocytoma misdiagnosed as neurocysticercosis: A case report

Authors:
- Hong‑Jiang Li
- Hong‑Xiu Han
- Dong‑Fu Feng
View Affiliations / Copyright

Affiliations: Department of Neurosurgery, No. 9 People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 201999, P.R. China, Department of Pathology, No. 9 People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 201999, P.R. China
Pages: 2825-2827
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Published online on: August 10, 2016

https://doi.org/10.3892/ol.2016.4986
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Abstract

Reports describing a rapid increase in the cystic volume of anaplastic astrocytoma (AA) in a short time frame are rare. The present study reports the case of a 68‑year‑old male who was admitted to the No. 9 People's Hospital, Shanghai Jiaotong University School of Medicine (Shanghai, China), with a small cystic brain lesion and positive immunological testing for cysticercosis. Head magnetic resonance imaging (MRI) showed a cystic lesion, 6 mm in diameter, in the left frontal lobe. Neurocysticercosis was suspected and the patient was treated with a clinical trial of albendazole and steroids. A period of 25 days later, the patient's condition had deteriorated, and MRI revealed a cystic lesion in the left frontal lobe; thereafter, the cystic lesion was removed and a diagnosis of AA was established. The tumor was soft, ivory white and gelatinous due to myxoid degeneration. In this case, tumor‑related angiogenesis and microvascular extravasation (blood‑brain barrier disruption) may have been the main cause of the rapid increase in the cystic volume in such a short time frame. The similarity of the glioma and cysticercus antigens may have been the cause of the positive reactions in the cystic fluid. The present study reports the rare occurrence of a rapid increase of cystic volume and potential diagnostic difficulties.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Rapid increase in cystic volume of an anaplastic astrocytoma misdiagnosed as neurocysticercosis: A case report

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