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Review Open Access

MicroRNAs and PIWI-interacting RNAs in oncology (Review)

  • Authors:
    • Yong Liu
  • View Affiliations / Copyright

    Affiliations: Department of Neurology, Xuzhou Central Hospital, The Affiliated Xuzhou Hospital of Medical College of Southeast University, Xuzhou, Jiangsu 221009, P.R. China
    Copyright: © Liu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 2289-2292
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    Published online on: August 11, 2016
       https://doi.org/10.3892/ol.2016.4996
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Abstract

RNA molecules that are unable to translate into proteins are classified as non‑coding RNA. Non-coding RNA (ncRNA) genes include highly abundant and functionally important RNAs such as transfer RNAs, microRNAs (miRNAs), siRNAs, snRNAs, exRNAs and piRNAs. The number of ncRNAs encoded within the human genome is unknown; however, recent transcriptomic and bioinformatic studies suggest the existence of thousands of ncRNAs. Furthermore, small ncRNAs, including miRNAs and PIWI‑interacting RNAs (piRNAs), play an imperative role in the regulation of gene expression of numerous biological and pathological processes. Investigation into the expression and function of small RNA in cancer cells has contributed to gaining a greater understanding of the roles of small RNAs in carcinogenesis. The present review is aimed primarily to discuss the importance of the expression and functions of these small RNAs in carcinogenesis. These studies may provide useful information for future therapies in cancer.
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Copy and paste a formatted citation
Spandidos Publications style
Liu Y: MicroRNAs and PIWI-interacting RNAs in oncology (Review). Oncol Lett 12: 2289-2292, 2016.
APA
Liu, Y. (2016). MicroRNAs and PIWI-interacting RNAs in oncology (Review). Oncology Letters, 12, 2289-2292. https://doi.org/10.3892/ol.2016.4996
MLA
Liu, Y."MicroRNAs and PIWI-interacting RNAs in oncology (Review)". Oncology Letters 12.4 (2016): 2289-2292.
Chicago
Liu, Y."MicroRNAs and PIWI-interacting RNAs in oncology (Review)". Oncology Letters 12, no. 4 (2016): 2289-2292. https://doi.org/10.3892/ol.2016.4996
Copy and paste a formatted citation
x
Spandidos Publications style
Liu Y: MicroRNAs and PIWI-interacting RNAs in oncology (Review). Oncol Lett 12: 2289-2292, 2016.
APA
Liu, Y. (2016). MicroRNAs and PIWI-interacting RNAs in oncology (Review). Oncology Letters, 12, 2289-2292. https://doi.org/10.3892/ol.2016.4996
MLA
Liu, Y."MicroRNAs and PIWI-interacting RNAs in oncology (Review)". Oncology Letters 12.4 (2016): 2289-2292.
Chicago
Liu, Y."MicroRNAs and PIWI-interacting RNAs in oncology (Review)". Oncology Letters 12, no. 4 (2016): 2289-2292. https://doi.org/10.3892/ol.2016.4996
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