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Case Report Open Access

Multiple large xanthomas: A case report

  • Authors:
    • Chen Zhao
    • Mingxiang Kong
    • Li Cao
    • Qiong Zhang
    • Yong Fang
    • Weiwei Ruan
    • Xiaofan Dou
    • Xiaohui Gu
    • Qing Bi
  • View Affiliations / Copyright

    Affiliations: Department of Orthopedics and Joint Surgery, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang 310014, P.R. China, Department of Orthopedics, The Second Clinical Medical College, Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China, Operating Room, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang 310014, P.R. China
    Copyright: © Zhao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 4327-4332
    |
    Published online on: October 18, 2016
       https://doi.org/10.3892/ol.2016.5282
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Abstract

A 23-year-old male patient presented with multiple large masses in his elbows, buttocks, knees, Achilles tendons, feet, shoulders and hands. The large masses in the elbows and buttocks measured ~6x5x5 cm and ~7x5x4 cm, respectively. The patient presented with an elevated level of low‑density lipoprotein cholesterol, and had been previously diagnosed with homozygous familial hypercholesterolemia (FH) and multiple xanthomas. Local surgical excisions were performed to remove the massive xanthomas from the elbows and buttocks, and histological analysis of the surgical specimens confirmed the previous diagnosis of homozygous FH (HoFH). The aim of the present study was to report a rare case of HoFH coinciding with multiple, large and widely‑distributed xanthomas and to discuss the clinical characteristics, in order to provide a better understanding of xanthomas and FH.
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Copy and paste a formatted citation
Spandidos Publications style
Zhao C, Kong M, Cao L, Zhang Q, Fang Y, Ruan W, Dou X, Gu X and Bi Q: Multiple large xanthomas: A case report. Oncol Lett 12: 4327-4332, 2016.
APA
Zhao, C., Kong, M., Cao, L., Zhang, Q., Fang, Y., Ruan, W. ... Bi, Q. (2016). Multiple large xanthomas: A case report. Oncology Letters, 12, 4327-4332. https://doi.org/10.3892/ol.2016.5282
MLA
Zhao, C., Kong, M., Cao, L., Zhang, Q., Fang, Y., Ruan, W., Dou, X., Gu, X., Bi, Q."Multiple large xanthomas: A case report". Oncology Letters 12.6 (2016): 4327-4332.
Chicago
Zhao, C., Kong, M., Cao, L., Zhang, Q., Fang, Y., Ruan, W., Dou, X., Gu, X., Bi, Q."Multiple large xanthomas: A case report". Oncology Letters 12, no. 6 (2016): 4327-4332. https://doi.org/10.3892/ol.2016.5282
Copy and paste a formatted citation
x
Spandidos Publications style
Zhao C, Kong M, Cao L, Zhang Q, Fang Y, Ruan W, Dou X, Gu X and Bi Q: Multiple large xanthomas: A case report. Oncol Lett 12: 4327-4332, 2016.
APA
Zhao, C., Kong, M., Cao, L., Zhang, Q., Fang, Y., Ruan, W. ... Bi, Q. (2016). Multiple large xanthomas: A case report. Oncology Letters, 12, 4327-4332. https://doi.org/10.3892/ol.2016.5282
MLA
Zhao, C., Kong, M., Cao, L., Zhang, Q., Fang, Y., Ruan, W., Dou, X., Gu, X., Bi, Q."Multiple large xanthomas: A case report". Oncology Letters 12.6 (2016): 4327-4332.
Chicago
Zhao, C., Kong, M., Cao, L., Zhang, Q., Fang, Y., Ruan, W., Dou, X., Gu, X., Bi, Q."Multiple large xanthomas: A case report". Oncology Letters 12, no. 6 (2016): 4327-4332. https://doi.org/10.3892/ol.2016.5282
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