Open Access

Multiple large xanthomas: A case report

  • Authors:
    • Chen Zhao
    • Mingxiang Kong
    • Li Cao
    • Qiong Zhang
    • Yong Fang
    • Weiwei Ruan
    • Xiaofan Dou
    • Xiaohui Gu
    • Qing Bi
  • View Affiliations

  • Published online on: October 18, 2016     https://doi.org/10.3892/ol.2016.5282
  • Pages: 4327-4332
  • Copyright: © Zhao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

A 23-year-old male patient presented with multiple large masses in his elbows, buttocks, knees, Achilles tendons, feet, shoulders and hands. The large masses in the elbows and buttocks measured ~6x5x5 cm and ~7x5x4 cm, respectively. The patient presented with an elevated level of low‑density lipoprotein cholesterol, and had been previously diagnosed with homozygous familial hypercholesterolemia (FH) and multiple xanthomas. Local surgical excisions were performed to remove the massive xanthomas from the elbows and buttocks, and histological analysis of the surgical specimens confirmed the previous diagnosis of homozygous FH (HoFH). The aim of the present study was to report a rare case of HoFH coinciding with multiple, large and widely‑distributed xanthomas and to discuss the clinical characteristics, in order to provide a better understanding of xanthomas and FH.
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December-2016
Volume 12 Issue 6

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Zhao C, Kong M, Cao L, Zhang Q, Fang Y, Ruan W, Dou X, Gu X and Bi Q: Multiple large xanthomas: A case report. Oncol Lett 12: 4327-4332, 2016
APA
Zhao, C., Kong, M., Cao, L., Zhang, Q., Fang, Y., Ruan, W. ... Bi, Q. (2016). Multiple large xanthomas: A case report. Oncology Letters, 12, 4327-4332. https://doi.org/10.3892/ol.2016.5282
MLA
Zhao, C., Kong, M., Cao, L., Zhang, Q., Fang, Y., Ruan, W., Dou, X., Gu, X., Bi, Q."Multiple large xanthomas: A case report". Oncology Letters 12.6 (2016): 4327-4332.
Chicago
Zhao, C., Kong, M., Cao, L., Zhang, Q., Fang, Y., Ruan, W., Dou, X., Gu, X., Bi, Q."Multiple large xanthomas: A case report". Oncology Letters 12, no. 6 (2016): 4327-4332. https://doi.org/10.3892/ol.2016.5282