|
1
|
Hanahan D and Weinberg RA: The hallmarks
of cancer. Cell. 100:57–70. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Crinò L, Weder W, van Meerbeeck J and
Felip E: ESMO Guidelines Working Group: Early stage and locally
advanced (non-metastatic) non-small-cell lung cancer: ESMO clinical
practice guidelines for diagnosis, treatment and follow-up. Ann
Oncol. 21:(Suppl 5). v103–v115. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Cool DR, Normant E, Shen F, Chen HC,
Pannell L, Zhang Y and Loh YP: Carboxypeptidase E is a regulated
secretory pathway sorting receptor: Genetic obliteration leads to
endocrine disorders in Cpe(fat) mice. Cell. 88:73–83. 1997.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Cawley NX, Wetsel WC, Murthy SR, Park JJ,
Pacak K and Loh YP: New roles of carboxypeptidase E in endocrine
and neural function and cancer. Endocr Rev. 33:216–253. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Murthy SR, Pacak K and Loh YP:
Carboxypeptidase E: Elevated expression correlated with tumor
growth and metastasis in pheochromocytomas and other cancers. Cell
Mol Neurobiol. 30:1377–1381. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Coleman DL and Eicher EM: Fat (fat) and
tubby (tub): Two autosomal recessive mutations causing obesity
syndromes in the mouse. J Hered. 81:424–427. 1990.PubMed/NCBI
|
|
7
|
Bachtiary B, Boutros PC, Pintilie M, Shi
W, Bastianutto C, Li JH, Schwock J, Zhang W, Penn LZ, Jurisica I,
et al: Gene expression profiling in cervical cancer: An exploration
of intratumor heterogeneity. Clin Cancer Res. 12:5632–5640. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Hong Y, Ho KS, Eu KW and Cheah PY: A
susceptibility gene set for early onset colorectal cancer that
integrates diverse signaling pathways: Implication for
tumorigenesis. Clin Cancer Res. 13:1107–1114. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Cool DR and Loh YP: Carboxypeptidase E is
a sorting receptor for prohormones: Binding and kinetic studies.
Mol Cell Endocrinol. 139:7–13. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Fricker LD and Snyder SH: Purification and
characterization of enkephalin convertase, an
enkephalin-synthesizing carboxypeptidase. J Biol Chem.
258:10950–10955. 1983.PubMed/NCBI
|
|
11
|
Tang SS, Zhang JH, Liu HX and Li HZ:
PC2/CPE-mediated pro-protein processing in tumor cells and its
differentiated cells or tissues. Mol Cell Endocrinol. 303:43–49.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
He P, Varticovski L, Bowman ED, Fukuoka J,
Welsh JA, Miura K, Jen J, Gabrielson E, Brambilla E, Travis WD and
Harris CC: Identification of carboxypeptidase E and gamma-glutamyl
hydrolase as biomarkers for pulmonary neuroendocrine tumors by cDNA
microarray. Hum Pathol. 35:1196–1209. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Cutcliffe C, Kersey D, Huang CC, Zeng Y,
Walterhouse D and Perlman EJ: Renal Tumor Committee of the
Children's Oncology Group: Clear cell sarcoma of the kidney:
Up-regulation of neural markers with activation of the sonic
hedgehog and Akt pathways. Clin Cancer Res. 11:7986–7994. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Walboomers JM, Jacobs MV, Manos MM, Bosch
FX, Kummer JA, Shah KV, Snijders PJ, Peto J, Meijer CJ and Muñoz N:
Human papillomavirus is a necessary cause of invasive cervical
cancer worldwide. J Pathol. 189:12–19. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Lee TK, Murthy SR, Cawley NX, Dhanvantari
S, Hewitt SM, Lou H, Lau T, Ma S, Huynh T, Wesley RA, et al: An
N-terminal truncated carboxypeptidase E splice isoform induces
tumor growth and is a biomarker for predicting future metastasis in
human cancers. J Clin Invest. 121:880–892. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Mitka M: Researchers discover new
biomarker that may improve cancer care strategies. JAMA.
305:1184–1185. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Zhou K, Liang H, Liu Y, Yang C, Liu P and
Jiang X: Overexpression of CPE-ΔN predicts poor prognosis in
colorectal cancer patients. Tumour Biol. 34:3691–3699. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Liang XH, Li LL, Wu GG, Xie YC, Zhang GX,
Chen W, Yang HF, Liu QL, Li WH, He WG, et al: Upregulation of CPE
promotes cell proliferation and tumorigenicity in colorectal
cancer. BMC Cancer. 13:4122013. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Sun J, Nie J, Hao B, Li L, Xing G, Wang Z,
Zhou Y, Sun Q, Li G, Zhang L and He F: Ceap/BLOS2 interacts with
BRD7 and selectively inhibits its transcription-suppressing effect
on cellular proliferation-associated genes. Cell Signal.
20:1151–1158. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Tong ZT, Cai MY, Wang XG, Kong LL, Mai SJ,
Liu YH, Zhang HB, Liao YJ, Zheng F, Zhu W, et al: EZH2 supports
nasopharyngeal carcinoma cell aggressiveness by forming a
co-repressor complex with HDAC1/HDAC2 and Snail to inhibit
E-cadherin. Oncogene. 31:583–594. 2012.PubMed/NCBI
|
|
21
|
Jazieh AR, Bamefleh H, Demirkazik A,
Gaafar RM, Geara FB, Javaid M, Khader J, Khodadad K, Omar W,
Saadeddin A, et al: MENA Lung Cancer Regional Guidelines Committee:
Modification and implementation of NCCN guidelines on non-small
cell lung cancer in the Middle East and North Africa region. J Natl
Compr Canc Netw. 8:(Suppl 3). S16–S21. 2010.PubMed/NCBI
|
|
22
|
Skalka N, Caspi M, Caspi E, Loh YP and
Rosin-Arbesfeld R: Carboxypeptidase E: A negative regulator of the
canonical Wnt signaling pathway. Oncogene. 32:2836–2847. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Chen H, Jawahar S, Qian Y, Duong Q, Chan
G, Parker A, Meyer JM, Moore KJ, Chayen S, Gross DJ, et al:
Missense polymorphism in the human carboxypeptidase E gene alters
enzymatic activity. Hum Mutat. 18:120–131. 2001. View Article : Google Scholar : PubMed/NCBI
|
