|
1
|
Siegel R, Naishadham D and Jemal A: Cancer
statistics 2013. CA Cancer J Clin. 63:11–30. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Diener MK, Combs SE and Büchler MW:
Chemoradiotherapy for locally advanced pancreatic cancer. Lancet
Oncol. 14:269–270. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Akimoto M, Iizuka M, Kanematsu R, Yoshida
M and Takenaga K: Anticancer effect of ginger extract against
pancreatic cancer cells mainly through reactive oxygen
species-mediated autotic cell death. PLoS One. 10:e01266052015.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Lewis CS, Voelkel-Johnson C and Smith CD:
Suppression of c-Myc and RRM2 expression in pancreatic cancer cells
by the sphingosine kinase-2 inhibitor ABC294640. Oncotarget.
2016.[Epub ahead of print]. View Article : Google Scholar
|
|
5
|
Mandhare A, Biradar S and Gurule A:
Azaepothilone B and its derivatives: A patent review. Expert Opin
Ther Pat. 26:891–905. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Pourmorteza M, Rahman ZU and Young M:
Evofosfamide, a new horizon in the treatment of pancreatic cancer.
Anticancer Drugs. 27:723–725. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Polier G, Ding J, Konkimalla BV, Eick D,
Ribeiro N, Köhler R, Giaisi M, Efferth T, Desaubry L, Krammer PH
and Li-Weber M: Wogonin and related natural flavones are inhibitors
of CDK9 that induce apoptosis in cancer cells by transcriptional
suppression of Mcl-1. Cell Death Dis. 2:e1822011. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Polier G, Giaisi M, Köhler R, Müller WW,
Lutz C, Buss EC, Krammer PH and Li-Weber M: Targeting CDK9 by
wogonin and related natural flavones potentiates the anti-cancer
efficacy of the Bcl-2 family inhibitor ABT-263. Int J Cancer.
136:688–698. 2015.PubMed/NCBI
|
|
9
|
Baumann S, Fas SC, Giaisi M, Müller WW,
Merling A, Gülow K, Edler L, Krammer PH and Li-Weber M: Wogonin
preferentially kills malignant lymphocytes and suppresses T-cell
tumor growth by inducing PLCgamma1-and Ca2+-dependent
apoptosis. Blood. 111:2354–2363. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Yang H, Hui H, Wang Q, Li H, Zhao K, Zhou
Y, Zhu Y, Wang X, You Q, Guo Q and Lu N: Wogonin induces cell cycle
arrest and erythroid differentiation in imatinib-resistant K562
cells and primary CML cells. Oncotarget. 5:8188–8201. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Takahashi H, Chen MC, Pham H, Angst E,
King JC, Park J, Brovman EY, Ishiguro H, Harris DM, Reber HA, et
al: Baicalein, a component of Scutellaria baicalensis, induces
apoptosis by Mcl-1 down-regulation in human pancreatic cancer
cells. Biochim Biophys Acta. 1813:1465–1474. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Kallifatidis G, Rausch V, Baumann B, Apel
A, Beckermann BM, Groth A, Mattern J, Li Z, Kolb A, Moldenhauer G,
et al: Sulforaphane targets pancreatic tumour-initiating cells by
NF-kappaB-induced antiapoptotic signalling. Gut. 58:949–963. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Chen N and Karantza V: Autophagy as a
therapeutic target in cancer. Cancer Biol Ther. 11:157–168. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Chow SE, Chen YW, Liang CA, Huang YK and
Wang JS: Wogonin induces cross-regulation between autophagy and
apoptosis via a variety of Akt pathway in human nasopharyngeal
carcinoma cells. J Cell Biochem. 113:3476–3485. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Zhu Y and Wang J: Wogonin increases
β-amyloid clearance and inhibits tau phosphorylation via inhibition
of mammalian target of rapamycin: Potential drug to treat
Alzheimer's disease. Neurol Sci. 36:1181–1188. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Klionsky DJ, Abdelmohsen K, Abe A, Abedin
MJ, Abeliovich H, Arozena A Acevedo, Adachi H, Adams CM, Adams PD,
Adeli K, et al: Guidelines for the use and interpretation of assays
for monitoring autophagy (3rd edition). Autophagy. 12:1–222. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Steinbrenner J, Eldridge M, Tomé DF and
Beynon JL: A simple and fast protocol for the protein complex
immunoprecipitation (Co-IP) of effector: Host protein complexes.
Methods Mol Biol. 1127:195–211. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Mikhaylova O, Stratton Y, Hall D, Kellner
E, Ehmer B, Drew AF, Gallo CA, Plas DR, Biesiada J, Meller J and
Czyzyk-Krzeska MF: VHL-regulated MiR-204 suppresses tumor growth
through inhibition of LC3B-mediated autophagy in renal clear cell
carcinoma. Cancer Cell. 21:532–546. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Russell RC, Tian Y, Yuan H, Park HW, Chang
YY, Kim J, Kim H, Neufeld TP, Dillin A and Guan KL: ULK1 induces
autophagy by phosphorylating Beclin-1 and activating VPS34 lipid
kinase. Nat Cell Biol. 15:741–750. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Lee DH, Lee TH, Jung CH and Kim YH:
Wogonin induces apoptosis by activating the AMPK and p53 signaling
pathways in human glioblastoma cells. Cell Signal. 24:2216–25.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Thomas HE, Mercer CA, Carnevalli LS, Park
J, Andersen JB, Conner EA, Tanaka K, Matsutani T, Iwanami A, Aronow
BJ, et al: mTOR inhibitors synergize on regression, reversal of
gene expression, and autophagy in hepatocellular carcinoma. Sci
Transl Med. 4:139ra842012. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Xiao W, Wu K, Yin M, Han S, Ding Y, Qiao
A, Lu G, Deng B, Bo P and Gong W: Wogonin Inhibits Tumor-derived
Regulatory Molecules by Suppressing STAT3 Signaling to Promote
Tumor Immunity. J Immunother. 38:167–84. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Hu C, Xu M, Qin R, Chen W and Xu X:
Wogonin induces apoptosis and endoplasmic reticulum stress in HL-60
leukemia cells through inhibition of the PI3K-AKT signaling
pathway. Oncol Rep. 33:3146–3154. 2015.PubMed/NCBI
|
|
24
|
Zhao L, Miao HC, Li WJ, Sun Y, Huang SL,
Li ZY and Guo QL: LW-213 induces G2/M cell cycle arrest through
AKT/GSK3β/β-catenin signaling pathway in human breast cancer cells.
Mol Carcinog. 55:778–792. 2015. View
Article : Google Scholar : PubMed/NCBI
|
|
25
|
Wang W, Xia T and Yu X: Wogonin suppresses
inflammatory response and maintains intestinal barrier function via
TLR4-MyD88-TAK1-mediated NF-κB pathway in vitro. Inflamm Res.
64:423–431. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Lee JY and Park W: Anti-inflammatory
effect of wogonin on RAW 264.7 mouse macrophages induced with
polyinosinic-polycytidylic acid. Molecules. 20:6888–6900. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Lucas CD, Dorward DA, Sharma S, Rennie J,
Felton JM, Alessandri AL, Duffin R, Schwarze J, Haslett C and Rossi
AG: Wogonin induces eosinophil apoptosis and attenuates allergic
airway inflammation. Am J Respir Crit Care Med. 191:626–636. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Prieto-Domínguez N, Ordóñez R, Fernández
A, García-Palomo A, Muntané J, González-Gallego J and Mauriz JL:
Modulation of autophagy by sorafenib: Effects on Treatment
Response. Front Pharmacol. 7:1512016. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Kleger A, Perkhofer L and Seufferlein T:
Smarter drugs emerging in pancreatic cancer therapy. Ann Oncol.
25:1260–1270. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Xi G, Hu X, Wu B, Jiang H, Young CY, Pang
Y and Yuan H: Autophagy inhibition promotes paclitaxel-induced
apoptosis in cancer cells. Cancer Lett. 307:141–148. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Maiuri MC, Tasdemir E, Criollo A, Morselli
E, Vicencio JM, Carnuccio R and Kroemer G: Control of autophagy by
oncogenes and tumor suppressor genes. Cell Death Differ. 16:87–93.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Scherz-Shouval R and Elazar Z: Regulation
of autophagy by ROS: Physiology and pathology. Trends Biochem Sci.
36:30–38. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Zhang J, Kim J, Alexander A, Cai S,
Tripathi DN, Dere R, Tee AR, Tait-Mulder J, Di Nardo A, Han JM, et
al: A tuberous sclerosis complex signalling node at the peroxisome
regulates mTORC1 and autophagyin response to ROS. Nat Cell Biol.
15:1186–1196. 2013. View
Article : Google Scholar : PubMed/NCBI
|
|
34
|
Kim SJ, Jung HJ and Lim CJ: Reactive
oxygen species-dependent down-regulation of tumor suppressor genes
PTEN, USP28, DRAM, TIGAR, and CYLD under oxidative stress. Biochem
Genet. 51:901–915. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Chen C, Liu Y and Zheng D: An agonistic
monoclonal antibody against DR5 induces ROS production, sustained
JNK activation and Endo G release in Jurkat leukemia cells. Cell
Res. 19:984–995. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Bonapace L, Bornhauser BC, Schmitz M,
Cario G, Ziegler U, Niggli FK, Schäfer BW, Schrappe M, Stanulla M
and Bourquin JP: Induction of autophagy-dependent necroptosis is
required for childhood acute lymphoblastic leukemia cells to
overcome glucocorticoid resistance. J Clin Invest. 120:1310–1323.
2010. View Article : Google Scholar : PubMed/NCBI
|
