Primary intraosseous squamous cell carcinoma of the mandible arising from an infected odontogenic cyst: A case report and review of the literature

Grisar,Koenraad; Schol,Matthias; Hauben,Esther; Schoenaers,Joseph; Politis,Constantinus

doi:10.3892/ol.2016.5378

Primary intraosseous squamous cell carcinoma of the mandible arising from an infected odontogenic cyst: A case report and review of the literature

Authors:
- Koenraad Grisar
- Matthias Schol
- Esther Hauben
- Joseph Schoenaers
- Constantinus Politis
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Affiliations: Department of Oral and Maxillofacial Surgery, University Hospitals Leuven, Leuven, 3000 Flemish Brabant, Belgium, Department of Dentistry, University Hospitals Leuven, Leuven, 3000 Flemish Brabant, Belgium, Department of Imaging and Pathology, University Hospitals Leuven, Leuven, 3000 Flemish Brabant, Belgium
Published online on: November 10, 2016 https://doi.org/10.3892/ol.2016.5378
Pages: 5327-5331

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Abstract

Primary intraosseous squamous cell carcinoma (PIOSCC) derived from a odontogenic cyst is a rare form of odontogenic carcinoma. The incidence of carcinomas arising from odontogenic cysts is particularly uncommon and is reported to occur in 1‑2 individuals for every 1,000 cases. The present case describes a 25‑year‑old man who was initially diagnosed with a chronically infected odontogenic cyst of the mandible. Biopsy and subsequent histology revealed the presence of squamous cell carcinoma. Therefore, neck dissection and hemimandibulectomy were performed. Ultimately, the situation in the mouth healed, though with a severe amount of scarring. Although the development of PIOSCC from an odontogenic cyst is rare, it should be included in the differential diagnosis for jaw bone radiolucency.

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