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Review

Long non-coding RNAs as novel biomarkers for breast cancer invasion and metastasis (Review)

  • Authors:
    • Kaijiong Zhang
    • Zhenglian Luo
    • Yi Zhang
    • Xiaoyu Song
    • Li Zhang
    • Lichun Wu
    • Jinbo Liu
  • View Affiliations / Copyright

    Affiliations: Department of Laboratory Medicine, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, P.R. China, Department of Laboratory Medicine, Sichuan Cancer Hospital, Chengdu, Sichuan 610041, P.R. China
  • Pages: 1895-1904
    |
    Published online on: June 22, 2017
       https://doi.org/10.3892/ol.2017.6462
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Abstract

Breast cancer (BC) is now the most common malignancy worldwide, with high prevalence and lethality among women. Invasion and metastasis are the major reasons for breast cancer‑associated mortality. However, the underlying mechanism of invasion and metastasis has not been entirely elucidated. Long non‑coding RNAs (lncRNAs) are a large class of non‑coding transcripts that are >200 bases in length and cannot encode proteins. Evidence has indicated that lncRNAs regulate gene expression at the levels of epigenetic modification, transcription and post‑transcription. In addition, they are involved in diverse tumor biological processes, including cell proliferation, apoptosis, invasion, metastasis and angiogenesis. The present review focuses on the recent progress of lncRNAs in breast cancer invasion and metastasis, aiming to provide novel strategies for the clinical prevention, diagnosis and treatment of breast cancer.
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Copy and paste a formatted citation
Spandidos Publications style
Zhang K, Luo Z, Zhang Y, Song X, Zhang L, Wu L and Liu J: Long non-coding RNAs as novel biomarkers for breast cancer invasion and metastasis (Review). Oncol Lett 14: 1895-1904, 2017.
APA
Zhang, K., Luo, Z., Zhang, Y., Song, X., Zhang, L., Wu, L., & Liu, J. (2017). Long non-coding RNAs as novel biomarkers for breast cancer invasion and metastasis (Review). Oncology Letters, 14, 1895-1904. https://doi.org/10.3892/ol.2017.6462
MLA
Zhang, K., Luo, Z., Zhang, Y., Song, X., Zhang, L., Wu, L., Liu, J."Long non-coding RNAs as novel biomarkers for breast cancer invasion and metastasis (Review)". Oncology Letters 14.2 (2017): 1895-1904.
Chicago
Zhang, K., Luo, Z., Zhang, Y., Song, X., Zhang, L., Wu, L., Liu, J."Long non-coding RNAs as novel biomarkers for breast cancer invasion and metastasis (Review)". Oncology Letters 14, no. 2 (2017): 1895-1904. https://doi.org/10.3892/ol.2017.6462
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang K, Luo Z, Zhang Y, Song X, Zhang L, Wu L and Liu J: Long non-coding RNAs as novel biomarkers for breast cancer invasion and metastasis (Review). Oncol Lett 14: 1895-1904, 2017.
APA
Zhang, K., Luo, Z., Zhang, Y., Song, X., Zhang, L., Wu, L., & Liu, J. (2017). Long non-coding RNAs as novel biomarkers for breast cancer invasion and metastasis (Review). Oncology Letters, 14, 1895-1904. https://doi.org/10.3892/ol.2017.6462
MLA
Zhang, K., Luo, Z., Zhang, Y., Song, X., Zhang, L., Wu, L., Liu, J."Long non-coding RNAs as novel biomarkers for breast cancer invasion and metastasis (Review)". Oncology Letters 14.2 (2017): 1895-1904.
Chicago
Zhang, K., Luo, Z., Zhang, Y., Song, X., Zhang, L., Wu, L., Liu, J."Long non-coding RNAs as novel biomarkers for breast cancer invasion and metastasis (Review)". Oncology Letters 14, no. 2 (2017): 1895-1904. https://doi.org/10.3892/ol.2017.6462
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