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Anastomosis in the absence of a suprahyoid release following circumferential sleeve resection is feasible in differentiated thyroid carcinoma patients with tracheal invasion

  • Authors:
    • Wanjun Chen
    • Shujuan Zou
    • Liang Wang
    • Changhua Wu
    • Zhiqi Wang
    • Ke Li
    • Shuguang Zhang
  • View Affiliations / Copyright

    Affiliations: Department of Head and Neck Surgery, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan, Shandong 250117, P.R. China
    Copyright: © Chen et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 2822-2830
    |
    Published online on: July 10, 2017
       https://doi.org/10.3892/ol.2017.6568
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Abstract

Invasion of the trachea is observed in ~6% of patients with differentiated thyroid carcinoma (DTC), and surgery is accepted as the treatment of choice. However, surgical procedures can be challenging and are associated with various risks. The authors of the present study performed a retrospective study of patients with DTC and tumor invasion of the trachea. Outcomes from patients that received circumferential sleeve resection (CSR) of the trachea followed by anastomosis in the absence of suprahyoid release (n=21; CSR group) and patients that underwent tangential resections [n=103; tangential ʻshaveʼ resection (TSR) group) were analyzed. In the CSR group, 4 to 8 tracheal rings were circumferentially resected. All patients underwent end‑to‑end anastomosis in the absence of suprahyoid release following CSR, and 7 patients developed cancer metastasis following surgery. With the exception of 2 patients that succumbed to disease, the remaining patients in the CSR group survived without cancer recurrence. In the TSR group, all of the patients experienced cancer recurrence within five years post‑surgery. A total of 61 patients developed metastases in the three years following surgery, and 71 patients succumbed to cancer metastasis within five years. The survival rate of the CSR group was significantly increased compared with the TSR group. The results of the present study suggest that in DTC patients with defects involving up to 8 tracheal rings, it may be appropriate to perform anastomosis without suprahyoid tissue release as it is associated with a reduced incidence of perioperative morbidity.
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Copy and paste a formatted citation
Spandidos Publications style
Chen W, Zou S, Wang L, Wu C, Wang Z, Li K and Zhang S: Anastomosis in the absence of a suprahyoid release following circumferential sleeve resection is feasible in differentiated thyroid carcinoma patients with tracheal invasion. Oncol Lett 14: 2822-2830, 2017.
APA
Chen, W., Zou, S., Wang, L., Wu, C., Wang, Z., Li, K., & Zhang, S. (2017). Anastomosis in the absence of a suprahyoid release following circumferential sleeve resection is feasible in differentiated thyroid carcinoma patients with tracheal invasion. Oncology Letters, 14, 2822-2830. https://doi.org/10.3892/ol.2017.6568
MLA
Chen, W., Zou, S., Wang, L., Wu, C., Wang, Z., Li, K., Zhang, S."Anastomosis in the absence of a suprahyoid release following circumferential sleeve resection is feasible in differentiated thyroid carcinoma patients with tracheal invasion". Oncology Letters 14.3 (2017): 2822-2830.
Chicago
Chen, W., Zou, S., Wang, L., Wu, C., Wang, Z., Li, K., Zhang, S."Anastomosis in the absence of a suprahyoid release following circumferential sleeve resection is feasible in differentiated thyroid carcinoma patients with tracheal invasion". Oncology Letters 14, no. 3 (2017): 2822-2830. https://doi.org/10.3892/ol.2017.6568
Copy and paste a formatted citation
x
Spandidos Publications style
Chen W, Zou S, Wang L, Wu C, Wang Z, Li K and Zhang S: Anastomosis in the absence of a suprahyoid release following circumferential sleeve resection is feasible in differentiated thyroid carcinoma patients with tracheal invasion. Oncol Lett 14: 2822-2830, 2017.
APA
Chen, W., Zou, S., Wang, L., Wu, C., Wang, Z., Li, K., & Zhang, S. (2017). Anastomosis in the absence of a suprahyoid release following circumferential sleeve resection is feasible in differentiated thyroid carcinoma patients with tracheal invasion. Oncology Letters, 14, 2822-2830. https://doi.org/10.3892/ol.2017.6568
MLA
Chen, W., Zou, S., Wang, L., Wu, C., Wang, Z., Li, K., Zhang, S."Anastomosis in the absence of a suprahyoid release following circumferential sleeve resection is feasible in differentiated thyroid carcinoma patients with tracheal invasion". Oncology Letters 14.3 (2017): 2822-2830.
Chicago
Chen, W., Zou, S., Wang, L., Wu, C., Wang, Z., Li, K., Zhang, S."Anastomosis in the absence of a suprahyoid release following circumferential sleeve resection is feasible in differentiated thyroid carcinoma patients with tracheal invasion". Oncology Letters 14, no. 3 (2017): 2822-2830. https://doi.org/10.3892/ol.2017.6568
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