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Article

iTRAQ‑coupled 2D LC/MS‑MS analysis of CXCR7‑transfected papillary thyroid carcinoma cells: A new insight into CXCR7 regulation of papillary thyroid carcinoma progression and identification of potential biomarkers

  • Authors:
    • Hengwei Zhang
    • Lei Yang
    • Zhangyi Liu
    • Chenxi Liu
    • Xuyong Teng
    • Lei Zhang
    • Bo Yin
    • Zhen Liu
  • View Affiliations / Copyright

    Affiliations: Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China, Department of General Surgery, The First Affiliated Hospital, China Medical University, Shenyang, Liaoning 110001, P.R. China, Department of Urology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China
  • Pages: 3734-3740
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    Published online on: July 15, 2017
       https://doi.org/10.3892/ol.2017.6574
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Abstract

Previous studies have demonstrated that C‑X‑C chemokine receptor type 7 (CXCR7) regulates papillary thyroid carcinoma (PTC) growth and metastasis; however, the molecular mechanisms underlying this regulation remain unclear. In the present study, the protein expression profiles of the PTC cell line GLAG‑66 and GLAG‑66 cells stably transfected with CXCR7 cDNA were analyzed and compared using isobaric tag for relative and absolute quantification‑coupled two‑dimensional liquid chromatography‑tandem mass spectrometry. In total, 2,983 proteins were quantified and 130 proteins were identified to be differentially expressed, of which 87 were significantly upregulated and 43 were significantly downregulated. Gene Ontology enrichment analysis revealed that the differentially expressed proteins were primarily enriched in a number of biological processes, including metabolism‑related processes, cellular component organization, transport, cellular development process and the immune response. The differentially expressed proteins identified included fibronectin 1, basigin, periplakin and serpin family B member 5, all of which are associated with cellular junctions and cancer progression. In addition, transgelin‑2 and AHNAK nucleoprotein 2 were identified as potential novel biomarkers for the prognosis and treatment of PTC.
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1 

Rahib L, Smith BD, Aizenberg R, Rosenzweig AB, Fleshman JM and Matrisian LM: Projecting cancer incidence and deaths to 2030: The unexpected burden of thyroid, liver, and pancreas cancers in the United States. Cancer Res. 74:2913–2921. 2014. View Article : Google Scholar : PubMed/NCBI

2 

Morris LG, Tuttle RM and Davies L: Changing trends in the incidence of thyroid cancer in the united states. JAMA Otolaryngol Head Neck Surg. 142:709–711. 2016. View Article : Google Scholar : PubMed/NCBI

3 

Podnos YD, Smith D, Wagman LD and Ellenhorn JD: The implication of lymph node metastasis on survival in patients with well-differentiated thyroid cancer. Am Surg. 71:731–734. 2005.PubMed/NCBI

4 

Zaydfudim V, Feurer ID, Griffin MR and Phay JE: The impact of lymph node involvement on survival in patients with papillary and follicular thyroid carcinoma. Surgery. 144:1070–1078. 2008. View Article : Google Scholar : PubMed/NCBI

5 

Vandercappellen J, Van Damme J and Struyf S: The role of CXC chemokines and their receptors in cancer. Cancer Lett. 267:226–244. 2008. View Article : Google Scholar : PubMed/NCBI

6 

Ben-Baruch A: Organ selectivity in metastasis: Regulation by chemokines and their receptors. Clin Exp Metastasis. 25:345–356. 2008. View Article : Google Scholar : PubMed/NCBI

7 

Sun X, Cheng G, Hao M, Zheng J, Zhou X, Zhang J, Taichman RS, Pienta KJ and Wang J: CXCL12/CXCR4/CXCR7 chemokine axis and cancer progression. Cancer Metastasis Rev. 29:709–722. 2010. View Article : Google Scholar : PubMed/NCBI

8 

Hao M, Zheng J, Hou K and Wang J, Chen X, Lu X, Bo J, Xu C, Shen K and Wang J: Role of chemokine receptor CXCR7 in bladder cancer progression. Biochem Pharmacol. 84:204–214. 2012. View Article : Google Scholar : PubMed/NCBI

9 

Zheng K, Li HY, Su XL, Wang XY, Tian T, Li F and Ren GS: Chemokine receptor CXCR7 regulates the invasion, angiogenesis and tumor growth of human hepatocellular carcinoma cells. J Exp Clin Cancer Res. 29:312010. View Article : Google Scholar : PubMed/NCBI

10 

Singh RK and Lokeshwar BL: The IL-8-regulated chemokine receptor CXCR7 stimulates EGFR signaling to promote prostate cancer growth. Cancer Res. 71:3268–3277. 2011. View Article : Google Scholar : PubMed/NCBI

11 

Liu Z, Sun DX, Teng XY, Xu WX, Meng XP and Wang BS: Expression of stromal cell derived factor 1 and CXCR7 in papillary thyroid carcinoma. Endocr Pathol. 23:247–253. 2012. View Article : Google Scholar : PubMed/NCBI

12 

Liu Z, Yang L, Teng X, Zhang H and Guan H: The involvement of CXCR7 in modulating the progression of papillary thyroid carcinoma. J Surg Res. 191:379–388. 2014. View Article : Google Scholar : PubMed/NCBI

13 

Zhang H, Teng X and Liu Z, Zhang L and Liu Z: Gene expression profile analyze the molecular mechanism of CXCR7 regulating papillary thyroid carcinoma growth and metastasis. J Exp Clin Cancer Res. 34:162015. View Article : Google Scholar : PubMed/NCBI

14 

Wyllie FS, Lemoine NR, Barton CM, Dawson T, Bond J and Wynford-Thomas D: Direct growth stimulation of normal human epithelial cells by mutant p53. Mol Carcinog. 7:83–88. 1993. View Article : Google Scholar : PubMed/NCBI

15 

Ross PL, Huang YN, Marchese JN, Williamson B, Parker K, Hattan S, Khainovski N, Pillai S, Dey S, Daniels S, et al: Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents. Mol Cell Proteomics. 3:1154–1169. 2004. View Article : Google Scholar : PubMed/NCBI

16 

Paik JY, Ko BH, Jung KH and Lee KH: Fibronectin stimulates endothelial cell 18F-FDG uptake through focal adhesion kinase-mediated phosphatidylinositol 3-kinase/Akt signaling. J Nucl Med. 50:618–624. 2009. View Article : Google Scholar : PubMed/NCBI

17 

Xu XC, Zhang YH, Zhang WB, Li T, Gao H and Wang YH: MicroRNA-133a functions as a tumor suppressor in gastric cancer. J Biol Regul Homeost Agents. 28:615–624. 2014.PubMed/NCBI

18 

Fei F, Li X, Xu L, Li D, Zhang Z, Guo X, Yang H, Chen Z and Xing J: CD147-CD98hc complex contributes to poor prognosis of nonsmall cell lung cancer patients through promoting cell proliferation Via the PI3K/Akt signaling pathway. Ann Surg Oncol. 21:4359–4368. 2014. View Article : Google Scholar : PubMed/NCBI

19 

Suzuki A, Horiuchi A, Ashida T, Miyamoto T, Kashima H, Nikaido T, Konishi I and Shiozawa T: Cyclin A2 confers cisplatin resistance to endometrial carcinoma cells via up-regulation of an Akt-binding protein, periplakin. J Cell Mol Med. 14:2305–2317. 2010. View Article : Google Scholar : PubMed/NCBI

20 

de Morrée A, Droog M, Grand Moursel L, Bisschop IJ, Impagliazzo A, Frants RR, Klooster R and van der Maarel SM: Self-regulated alternative splicing at the AHNAK locus. FASEB J. 26:93–103. 2012. View Article : Google Scholar : PubMed/NCBI

21 

Takayama T, Shiozaki H, Shibamoto S, Oka H, Kimura Y, Tamura S, Inoue M, Monden T, Ito F and Monden M: Beta-catenin expression in human cancers. Am J Pathol. 148:39–46. 1996.PubMed/NCBI

22 

Zou Z, Anisowicz A, Hendrix MJ, Thor A, Neveu M, Sheng S, Rafidi K, Seftor E and Sager R: Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells. Science. 263:526–529. 1994. View Article : Google Scholar : PubMed/NCBI

23 

Wang YH, Dong YY, Wang WM, Xie XY, Wang ZM, Chen RX, Chen J, Gao DM, Cui JF and Ren ZG: Vascular endothelial cells facilitated HCC invasion and metastasis through the Akt and NF-κB pathways induced by paracrine cytokines. J Exp Clin Cancer Res. 32:512013. View Article : Google Scholar : PubMed/NCBI

24 

Prasad ML, Huang Y, Pellegata NS, de la Chapelle A and Kloos RT: Hashimoto's thyroiditis with papillary thyroid carcinoma (PTC)-like nuclear alterations express molecular markers of PTC. Histopathology. 45:39–46. 2004. View Article : Google Scholar : PubMed/NCBI

25 

Huang Y, Prasad M, Lemon WJ, Hampel H, Wright FA, Kornacker K, LiVolsi V, Frankel W, Kloos RT, Eng C, et al: Gene expression in papillary thyroid carcinoma reveals highly consistent profiles. Proc Natl Acad Sci USA. 98:15044–15049. 2001. View Article : Google Scholar : PubMed/NCBI

26 

Zhang Q, Zhou J, Ku XM, Chen XG, Zhang L, Xu J, Chen GS, Li Q, Qian F, Tian R, et al: Expression of CD147 as a significantly unfavorable prognostic factor in hepatocellular carcinoma. Eur J Cancer Prev. 16:196–202. 2007. View Article : Google Scholar : PubMed/NCBI

27 

Wu J, Hao ZW, Zhao YX, Yang XM, Tang H, Zhang X, Song F, Sun XX, Wang B, Nan G, et al: Full-length soluble CD147 promotes MMP-2 expression and is a potential serological marker in detection of hepatocellular carcinoma. J Transl Med. 12:1902014. View Article : Google Scholar : PubMed/NCBI

28 

Wang L, Wu G, Yu L, Yuan J, Fang F, Zhai Z, Wang F and Wang H: Inhibition of CD147 expression reduces tumor cell invasion in human prostate cancer cell line via RNA interference. Cancer Biol Ther. 5:608–614. 2006. View Article : Google Scholar : PubMed/NCBI

29 

Fang F and Wang L, Zhang S, Fang Q, Hao F, Sun Y, Zhao L, Chen S, Liao H and Wang L: CD147 modulates autophagy through the PI3K/Akt/mTOR pathway in human prostate cancer PC-3 cells. Oncol Lett. 9:1439–1443. 2015.PubMed/NCBI

30 

Tan H, Ye K, Wang Z and Tang H: CD147 expression as a significant prognostic factor in differentiated thyroid carcinoma. Transl Res. 152:143–149. 2008. View Article : Google Scholar : PubMed/NCBI

31 

Huang P, Chang S, Jiang X, Su J, Dong C, Liu X, Yuan Z, Zhang Z and Liao H: RNA interference targeting CD147 inhibits the proliferation, invasiveness, and metastatic activity of thyroid carcinoma cells by down-regulating glycolysis. Int J Clin Exp Pathol. 8:309–318. 2015.PubMed/NCBI

32 

van den Heuvel AP, de Vries-Smits AM, van Weeren PC, Dijkers PF, de Bruyn KM, Riedl JA and Burgering BM: Binding of protein kinase B to the plakin family member periplakin. J Cell Sci. 115:3957–3966. 2002. View Article : Google Scholar : PubMed/NCBI

33 

Suzuki A, Horiuchi A, Ashida T, Miyamoto T, Kashima H, Nikaido T, Konishi I and Shiozawa T: Cyclin A2 confers cisplatin resistance to endometrial carcinoma cells via up-regulation of an Akt-binding protein, periplakin. J Cell Mol Med. 14:2305–2317. 2010. View Article : Google Scholar : PubMed/NCBI

34 

Tonoike Y, Matsushita K, Tomonaga T, Katada K, Tanaka N, Shimada H, Nakatani Y, Okamoto Y and Nomura F: Adhesion molecule periplakin is involved in cellular movement and attachment in pharyngeal squamous cancer cells. BMC Cell Biol. 12:412011. View Article : Google Scholar : PubMed/NCBI

35 

Zhang M, Volpert O, Shi YH and Bouck N: Maspin is an angiogenesis inhibitor. Nat Med. 6:196–199. 2000. View Article : Google Scholar : PubMed/NCBI

36 

Sheng S, Carey J, Seftor EA, Dias L, Hendrix MJ and Sager R: Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostatic cancer cells. Proc Natl Acad Sci USA. 93:11669–11674. 1996. View Article : Google Scholar : PubMed/NCBI

37 

Cher ML, Biliran HR Jr, Bhagat S, Meng Y, Che M, Lockett J, Abrams J, Fridman R, Zachareas M and Sheng S: Maspin expression inhibits osteolysis, tumor growth, and angiogenesis in a model of prostate cancer bone metastasis. Proc Natl Acad Sci USA. 100:7847–7852. 2003. View Article : Google Scholar : PubMed/NCBI

38 

Boltze C, Schneider-Stock R, Meyer F, Peters B, Quednow C, Hoang-Vu C and Roessner A: Maspin in thyroid cancer: Its relationship with p53 and clinical outcome. Oncol Rep. 10:1783–1787. 2003.PubMed/NCBI

39 

Shams TM, Samaka RM and Shams ME: Maspin protein expression: A special feature of papillary thyroid carcinoma. J Egypt Natl Canc Inst. 18:274–280. 2006.PubMed/NCBI

40 

Liotta LA and Stetler-Stevenson WG: Tumor invasion and metastasis: An imbalance of positive and negative regulation. Cancer Res. 51:(18 Suppl). 5054s–5059s. 1991.PubMed/NCBI

41 

Kleinberg L, Holth A, Fridman E, Schwartz I, Shih IeM and Davidson B: The diagnostic role of claudins in serous effusions. Am J Clin Pathol. 127:928–937. 2007. View Article : Google Scholar : PubMed/NCBI

42 

Ohtani S, Terashima M, Satoh J, Soeta N, Saze Z, Kashimura S, Ohsuka F, Hoshino Y, Kogure M and Gotoh M: Expression of tight-junction-associated proteins in human gastric cancer: Downregulation of claudin-4 correlates with tumor aggressiveness and survival. Gastric Cancer. 12:43–51. 2009. View Article : Google Scholar : PubMed/NCBI

43 

Huber O, Bierkamp C and Kemler R: Cadherins and catenins in development. Curr Opin Cell Biol. 8:685–691. 1996. View Article : Google Scholar : PubMed/NCBI

44 

Miller JR and Moon RT: Signal transduction through beta-catenin and specification of cell fate during embryogenesis. Genes Dev. 10:2527–2539. 1996. View Article : Google Scholar : PubMed/NCBI

45 

Rho JH, Roehrl MH and Wang JY: Tissue proteomics reveals differential and compartment-specific expression of the homologs transgelin and transgelin-2 in lung adenocarcinoma and its stroma. J Proteome Res. 8:5610–5618. 2009. View Article : Google Scholar : PubMed/NCBI

46 

Zhang Y, Ye Y, Shen D, Jiang K, Zhang H, Sun W, Zhang J, Xu F, Cui Z and Wang S: Identification of transgelin-2 as a biomarker of colorectal cancer by laser capture microdissection and quantitative proteome analysis. Cancer Sci. 101:523–529. 2010. View Article : Google Scholar : PubMed/NCBI

47 

Nohata N, Sone Y, Hanazawa T, Fuse M, Kikkawa N, Yoshino H, Chiyomaru T, Kawakami K, Enokida H, Nakagawa M, et al: miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma. Oncotarget. 2:29–42. 2011. View Article : Google Scholar : PubMed/NCBI

48 

Li AY, Yang Q and Yang K: miR-133a mediates the hypoxia-induced apoptosis by inhibiting TAGLN2 expression in cardiac myocytes. Mol Cell Biochem. 400:173–181. 2015. View Article : Google Scholar : PubMed/NCBI

49 

Shtivelman E, Cohen FE and Bishop JM: A human gene (AHNAK) encoding an unusually large protein with a 1.2-microns polyionic rod structure. Proc Natl Acad Sci USA. 89:5472–5476. 1992. View Article : Google Scholar : PubMed/NCBI

50 

Komuro A, Masuda Y, Kobayashi K, Babbitt R, Gunel M, Flavell RA and Marchesi VT: The AHNAKs are a class of giant propeller-like proteins that associate with calcium channel proteins of cardiomyocytes and other cells. Proc Natl Acad Sci USA. 101:4053–4058. 2004. View Article : Google Scholar : PubMed/NCBI

51 

Marg A, Haase H, Neumann T, Kouno M and Morano I: AHNAK1 and AHNAK2 are costameric proteins: AHNAK1 affects transverse skeletal muscle fiber stiffness. Biochem Biophys Res Commun. 401:143–158. 2010. View Article : Google Scholar : PubMed/NCBI

52 

Straub BK, Boda J, Kuhn C, Schnoelzer M, Korf U, Kempf T, Spring H, Hatzfeld M and Franke WW: A novel cell-cell junction system: The cortex adherens mosaic of lens fiber cells. J Cell Sci. 116:4985–4995. 2003. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Zhang H, Yang L, Liu Z, Liu C, Teng X, Zhang L, Yin B and Liu Z: iTRAQ‑coupled 2D LC/MS‑MS analysis of CXCR7‑transfected papillary thyroid carcinoma cells: A new insight into CXCR7 regulation of papillary thyroid carcinoma progression and identification of potential biomarkers. Oncol Lett 14: 3734-3740, 2017.
APA
Zhang, H., Yang, L., Liu, Z., Liu, C., Teng, X., Zhang, L. ... Liu, Z. (2017). iTRAQ‑coupled 2D LC/MS‑MS analysis of CXCR7‑transfected papillary thyroid carcinoma cells: A new insight into CXCR7 regulation of papillary thyroid carcinoma progression and identification of potential biomarkers. Oncology Letters, 14, 3734-3740. https://doi.org/10.3892/ol.2017.6574
MLA
Zhang, H., Yang, L., Liu, Z., Liu, C., Teng, X., Zhang, L., Yin, B., Liu, Z."iTRAQ‑coupled 2D LC/MS‑MS analysis of CXCR7‑transfected papillary thyroid carcinoma cells: A new insight into CXCR7 regulation of papillary thyroid carcinoma progression and identification of potential biomarkers". Oncology Letters 14.3 (2017): 3734-3740.
Chicago
Zhang, H., Yang, L., Liu, Z., Liu, C., Teng, X., Zhang, L., Yin, B., Liu, Z."iTRAQ‑coupled 2D LC/MS‑MS analysis of CXCR7‑transfected papillary thyroid carcinoma cells: A new insight into CXCR7 regulation of papillary thyroid carcinoma progression and identification of potential biomarkers". Oncology Letters 14, no. 3 (2017): 3734-3740. https://doi.org/10.3892/ol.2017.6574
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang H, Yang L, Liu Z, Liu C, Teng X, Zhang L, Yin B and Liu Z: iTRAQ‑coupled 2D LC/MS‑MS analysis of CXCR7‑transfected papillary thyroid carcinoma cells: A new insight into CXCR7 regulation of papillary thyroid carcinoma progression and identification of potential biomarkers. Oncol Lett 14: 3734-3740, 2017.
APA
Zhang, H., Yang, L., Liu, Z., Liu, C., Teng, X., Zhang, L. ... Liu, Z. (2017). iTRAQ‑coupled 2D LC/MS‑MS analysis of CXCR7‑transfected papillary thyroid carcinoma cells: A new insight into CXCR7 regulation of papillary thyroid carcinoma progression and identification of potential biomarkers. Oncology Letters, 14, 3734-3740. https://doi.org/10.3892/ol.2017.6574
MLA
Zhang, H., Yang, L., Liu, Z., Liu, C., Teng, X., Zhang, L., Yin, B., Liu, Z."iTRAQ‑coupled 2D LC/MS‑MS analysis of CXCR7‑transfected papillary thyroid carcinoma cells: A new insight into CXCR7 regulation of papillary thyroid carcinoma progression and identification of potential biomarkers". Oncology Letters 14.3 (2017): 3734-3740.
Chicago
Zhang, H., Yang, L., Liu, Z., Liu, C., Teng, X., Zhang, L., Yin, B., Liu, Z."iTRAQ‑coupled 2D LC/MS‑MS analysis of CXCR7‑transfected papillary thyroid carcinoma cells: A new insight into CXCR7 regulation of papillary thyroid carcinoma progression and identification of potential biomarkers". Oncology Letters 14, no. 3 (2017): 3734-3740. https://doi.org/10.3892/ol.2017.6574
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