Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
October-2017 Volume 14 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
October-2017 Volume 14 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Hepatectomy for spontaneous rupture of hepatocellular carcinoma without portal triad clamping

  • Authors:
    • Zhi‑Ming Wang
    • Xin‑Sheng Lu
    • Fu Qiu
  • View Affiliations / Copyright

    Affiliations: Department of General Surgery, Xiangya Hospital, Central South University, Changsha 410008, P.R. China, Department of General Surgery, Xiangya Third Hospital, Central South University, Changsha 410013, P.R. China
    Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 3997-4004
    |
    Published online on: July 24, 2017
       https://doi.org/10.3892/ol.2017.6654
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Hepatectomy without portal triad clamping may decrease the incidence of liver injury; however, the effects of hepatectomy without portal triad clamping in the treatment of spontaneous rupture of hepatocellular carcinoma (SRHCC) remain unclear. The aims of the present study were to evaluate the therapeutic value of hepatectomy without portal triad clamping in the treatment of patients with SRHCC. The present study retrospectively reviewed patients with SRHCC who received hepatectomy without portal triad clamping (non‑clamping group) and the therapeutic efficacy was compared with that of 20 patients with SRHCC undergoing the same surgery in the presence of portal triad clamping (clamping group). Following hepatectomy, the non‑clamping group exhibited a significantly lower incidence of acute liver failure compared with the clamping group (P<0.05). No significant differences in operative time, intra‑operative blood loss, disease‑free or overall survival times between the two groups were identified (all P>0.05). At 1 week and 2 weeks after surgery, the non‑clamping group exhibited significantly lower alanine aminotransferase, aspartate aminotransferase and total bilirubin serum levels compared with the clamping group (all P<0.05). Hepatectomy without portal triad clamping may decrease the incidence of liver injury and liver failure in patients with SRHCC, suggesting that it may be a safe and effective therapeutic strategy.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

View References

1 

Yeh CN, Lee WC, Jeng LB, Chen MF and Yu MC: Spontaneous tumour rupture and prognosis in patients with hepatocellular carcinoma. Br J Surg. 89:1125–1129. 2002. View Article : Google Scholar : PubMed/NCBI

2 

Kim PT, Su JC, Buczkowski AK, Schaeffer DF, Chung SW, Scudamore CH and Ho SG: Computed tomography and angiographic interventional features of ruptured hepatocellular carcinoma: Pictorial essay. Can Assoc Radiol J. 57:159–168. 2006.PubMed/NCBI

3 

Lee WM, Stravitz RT and Larson AM: Introduction to the revised American association for the study of liver diseases position paper on acute liver failure, 2011. Hepatology. 55:965–967. 2012. View Article : Google Scholar : PubMed/NCBI

4 

Lü XS, Zheng YS and Fan QQ: Liver resection for spontaneous rupture of primary hepatocellular carcinoma. The Chinese-German Journal of Clinical Oncology. 2:23–24. 2003. View Article : Google Scholar

5 

Battula N, Madanur M, Priest O, Srinivasan P, O'Grady J, Heneghan MA, Bowles M, Muiesan P, Heaton N and Rela M: Spontaneous rupture of hepatocellular carcinoma: A western experience. Am J Surg. 197:164–167. 2009. View Article : Google Scholar : PubMed/NCBI

6 

Bulger EM, May S, Kerby JD, Emerson S, Stiell IG, Schreiber MA, Brasel KJ, Tisherman SA, Coimbra R, Rizoli S, et al: Out-of-hospital hypertonic resuscitation after traumatic hypovolemic shock: A randomized, placebo controlled trial. Ann Surg. 253:431–441. 2011. View Article : Google Scholar : PubMed/NCBI

7 

Zhang J, Ye L, Zhang J, Lin M, He S, Mao X, Zhou X and Zhi F: MELD scores and Child-Pugh classifications predict the outcomes of ERCP in cirrhotic patients with choledocholithiasis: A retrospective cohort study. Medicine (Baltimore). 94:e4332015. View Article : Google Scholar : PubMed/NCBI

8 

Ngan H, Tso WK, Lai CL and Fan ST: The role of hepatic arterial embolization in the treatment of spontaneous rupture of hepatocellular carcinoma. Clin Radiol. 53:338–341. 1998. View Article : Google Scholar : PubMed/NCBI

9 

Kim JY, Lee JS, Oh DH, Yim YH and Lee HK: Transcatheter arterial chemoembolization confers survival benefit in patients with a spontaneously ruptured hepatocellular carcinoma. Eur J Gastroenterol Hepatol. 24:640–645. 2012. View Article : Google Scholar : PubMed/NCBI

10 

Hsueh KC, Fan HL, Chen TW, Chan DC, Yu JC, Tsou SS, Chang TM and Hsieh CB: Management of spontaneously ruptured hepatocellular carcinoma and hemoperitoneum manifested as acute abdomen in the emergency room. World J Surg. 36:2670–2676. 2012. View Article : Google Scholar : PubMed/NCBI

11 

Andersson R, Tranberg KG and Bengmark S: Hemoperitoneum after spontaneous rupture of liver tumor: Results of surgical treatment. HPB Surg. 1:81–83. 1988. View Article : Google Scholar : PubMed/NCBI

12 

Shirabe K, Kitamura M, Tsutsui S, Maeda T, Matsumata T and Sugimachi K: A long-term survivor of ruptured hepatocellular carcinoma after hepatic resection. J Gastroenterol Hepatol. 10:351–354. 1995. View Article : Google Scholar : PubMed/NCBI

13 

Chen ZY, Qi QH and Dong ZL: Etiology and management of hemorrhage in spontaneous liver rupture: A report of 70 cases. World J Gastroenterol. 8:1063–1066. 2002. View Article : Google Scholar : PubMed/NCBI

14 

Marini P, Vilgrain V and Belghiti J: Management of spontaneous rupture of liver tumours. Dig Surg. 19:109–113. 2002. View Article : Google Scholar : PubMed/NCBI

15 

Leung CS, Tang CN, Fung KH and Li MK: A retrospective review of transcatheter hepatic arterial embolisation for ruptured hepatocellular carcinoma. J R Coll Surg Edinb. 47:685–688. 2002.PubMed/NCBI

16 

Tanaka A, Takeda R, Mukaihara S, Hayakawa K, Shibata T, Itoh K, Nishida N, Nakao K, Fukuda Y, Chiba T and Yamaoka Y: Treatment of ruptured hepatocellular carcinoma. Int J Clin Oncol. 6:291–295. 2001. View Article : Google Scholar : PubMed/NCBI

17 

Lee HS, Choi GH, Kang DR, Han KH, Ahn SH, Kim DY, Park JY, Kim SU and Choi JS: Impact of spontaneous hepatocellular carcinoma rupture on recurrence pattern and long-term surgical outcomes after partial hepatectomy. World J Surg. 38:2070–2078. 2014. View Article : Google Scholar : PubMed/NCBI

18 

Sonoda T, Kanematsu T, Takenaka K and Sugimachi K: Ruptured hepatocellular carcinoma evokes risk of implanted metastases. J Surg Oncol. 41:183–186. 1989. View Article : Google Scholar : PubMed/NCBI

19 

Okano J, Shiota G, Horie Y, Mitsuda A, Suou T, Kawasaki H and Oofuji S: Rupture of metastatic nodule on the peritoneal surface secondary to hepatocellular carcinoma. Intern Med. 35:783–784. 1996. View Article : Google Scholar : PubMed/NCBI

20 

Yunoki Y, Takeuchi H, Makino Y, Murakami I, Yasui Y, Tanakaya K, Kawaguchi K and Konaga E: Intraperitoneal seeding of ruptured hepatocellular carcinoma: Case report. Abdom Imaging. 24:398–400. 1999. View Article : Google Scholar : PubMed/NCBI

21 

Eriguchi N, Aoyagi S, Okuda K, Tamae T, Fukuda S, Kanazawa N, Hamada S, Kawabata M, Nishimura K and Kodama T: Successful surgical treatment for implanted intraperitoneal metastases of hepatocellular carcinoma. J Hepatobiliary Pancreat Surg. 7:520–523. 2000. View Article : Google Scholar : PubMed/NCBI

22 

Lin CC, Chen CH, Tsang YM, Jan IS and Sheu JC: Diffuse intraperitoneal metastasis after spontaneous rupture of hepatocellular carcinoma. J Formos Med Assoc. 105:577–582. 2006. View Article : Google Scholar : PubMed/NCBI

23 

Chang YM, Hsu KF, Yu JC, Chan DC, Chen CJ, Chen TW, Hsieh CB and Hsieh HF: Distilled water peritoneal lavage in patients with rupture hepatocellular carcinoma. Hepatogastroenterology. 60:140–143. 2013.PubMed/NCBI

24 

Yang T, Sun YF, Zhang J, Lau WY, Lai EC, Lu JH, Shen F and Wu MC: Partial hepatectomy for ruptured hepatocellular carcinoma. Br J Surg. 100:1071–1079. 2013. View Article : Google Scholar : PubMed/NCBI

25 

Qian NS, Liao YH, Cai SW, Raut V and Dong JH: Comprehensive application of modern technologies in precise liver resection. Hepatobiliary Pancreat Dis Int. 12:244–250. 2013. View Article : Google Scholar : PubMed/NCBI

26 

Tashiro H, Kuroda S, Mikuriya Y and Ohdan H: Ischemia-reperfusion injury in patients with fatty liver and the clinical impact of steatotic liver on hepatic surgery. Surg Today. 44:1611–1625. 2014. View Article : Google Scholar : PubMed/NCBI

27 

Ramakrishna G, Rastogi A, Trehanpati N, Sen B, Khosla R and Sarin SK: From cirrhosis to hepatocellular carcinoma: New molecular insights on inflammation and cellular senescence. Liver Cancer. 2:367–383. 2013. View Article : Google Scholar : PubMed/NCBI

28 

Wrightson WR, Edwards MJ and McMasters KM: The role of the ultrasonically activated shears and vascular cutting stapler in hepatic resection. Am Surg. 66:1037–1040. 2000.PubMed/NCBI

29 

Zhu Q, Li J, Yan JJ, Huang L, Wu MC and Yan YQ: Predictors and clinical outcomes for spontaneous rupture of hepatocellular carcinoma. World J Gastroenterol. 18:7302–7307. 2012. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Wang ZM, Lu XS and Qiu F: Hepatectomy for spontaneous rupture of hepatocellular carcinoma without portal triad clamping. Oncol Lett 14: 3997-4004, 2017.
APA
Wang, Z., Lu, X., & Qiu, F. (2017). Hepatectomy for spontaneous rupture of hepatocellular carcinoma without portal triad clamping. Oncology Letters, 14, 3997-4004. https://doi.org/10.3892/ol.2017.6654
MLA
Wang, Z., Lu, X., Qiu, F."Hepatectomy for spontaneous rupture of hepatocellular carcinoma without portal triad clamping". Oncology Letters 14.4 (2017): 3997-4004.
Chicago
Wang, Z., Lu, X., Qiu, F."Hepatectomy for spontaneous rupture of hepatocellular carcinoma without portal triad clamping". Oncology Letters 14, no. 4 (2017): 3997-4004. https://doi.org/10.3892/ol.2017.6654
Copy and paste a formatted citation
x
Spandidos Publications style
Wang ZM, Lu XS and Qiu F: Hepatectomy for spontaneous rupture of hepatocellular carcinoma without portal triad clamping. Oncol Lett 14: 3997-4004, 2017.
APA
Wang, Z., Lu, X., & Qiu, F. (2017). Hepatectomy for spontaneous rupture of hepatocellular carcinoma without portal triad clamping. Oncology Letters, 14, 3997-4004. https://doi.org/10.3892/ol.2017.6654
MLA
Wang, Z., Lu, X., Qiu, F."Hepatectomy for spontaneous rupture of hepatocellular carcinoma without portal triad clamping". Oncology Letters 14.4 (2017): 3997-4004.
Chicago
Wang, Z., Lu, X., Qiu, F."Hepatectomy for spontaneous rupture of hepatocellular carcinoma without portal triad clamping". Oncology Letters 14, no. 4 (2017): 3997-4004. https://doi.org/10.3892/ol.2017.6654
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team