|
1
|
Li Z and Zhu WG: Targeting histone
deacetylases for cancer therapy: From molecular mechanisms to
clinical implications. Int J Biol Sci. 10:757–770. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Ouyang L, Shi Z, Zhao S, Wang FT, Zhou TT,
Liu B and Bao JK: Programmed cell death pathways in cancer: A
review of apoptosis, autophagy and programmed necrosis. Cell
Prolif. 45:487–498. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Hailey DW, Rambold AS, Satpute-Krishnan P,
Mitra K, Sougrat R, Kim PK and Lippincott-Schwartz J: Mitochondria
supply membranes for autophagosome biogenesis during starvation.
Cell. 141:656–667. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Maiuri MC, Criollo A and Kroemer G:
Crosstalk between apoptosis and autophagy within the Beclin 1
interactome. EMBO J. 29:515–516. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Yang Z and Klionsky DJ: Eaten alive: A
history of macroautophagy. Nat Cell Biol. 12:814–822. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Kang R, Zeh HJ, Lotze MT and Tang D: The
Beclin 1 network regulates autophagy and apoptosis. Cell Death
Differ. 18:571–580. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−Delta Delta C(T)) Method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Jemal A, Center MM, DeSantis C and Ward
EM: Global patterns of cancer incidence and mortality rates and
trends. Cancer Epidemiol Biomarkers Prev. 19:1893–1907. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Ren JS, Chen WQ, Shin HR, Ferlay J, Saika
K, Zhang SW and Bray F: A comparison of two methods to estimate the
cancer incidence and mortality burden in China in 2005. Asian Pac J
Cancer Prev. 11:1587–1594. 2010.PubMed/NCBI
|
|
10
|
Levine B and Kroemer G: Autophagy in the
pathogenesis of disease. Cell. 132:27–42. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Yoshimori T: Autophagy: A regulated bulk
degradation process inside cells. Biochem Biophys Res Commun.
313:453–458. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Gozuacik D and Kimchi A: Autophagy as a
cell death and tumor suppressor mechanism. Oncogene. 23:2891–2906.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Thompson CB: Apoptosis in the pathogenesis
and treatment of disease. Science. 267:1456–1462. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Behrends C, Sowa ME, Gygi SP and Harper
JW: Network organization of the human autophagy system. Nature.
466:68–76. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Yue Z, Jin S, Yang C, Levine AJ and Heintz
N: Beclin 1, an autophagy gene essential for early embryonic
development, is a haploinsufficient tumor suppressor. Proc Natl
Acad Sci USA. 100:15077–15082. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Zeng X, Overmeyer JH and Maltese WA:
Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase
complex in macroautophagy versus endocytosis and lysosomal enzyme
trafficking. J Cell Sci. 119:259–270. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Liang XH, Jackson S, Seaman M, Brown K,
Kempkes B, Hibshoosh H and Levine B: Induction of autophagy and
inhibition of tumorigenesis by beclin 1. Nature. 402:672–676. 1999.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Qu X, Yu J, Bhagat G, Furuya N, Hibshoosh
H, Troxel A, Rosen J, Eskelinen EL, Mizushima N, Ohsumi Y, et al:
Promotion of tumorigenesis by heterozygous disruption of the beclin
1 autophagy gene. J Clin Invest. 112:1809–1820. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Yu L, Alva A, Su H, Dutt P, Freundt E,
Welsh S, Baehrecke EH and Lenardo MJ: Regulation of an ATG7-beclin
1 program of autophagic cell death by caspase-8. Science.
304:1500–1502. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Shimizu S, Kanaseki T, Mizushima N, Mizuta
T, Arakawa-Kobayashi S, Thompson CB and Tsujimoto Y: Role of Bcl-2
family proteins in a non-apoptotic programmed cell death dependent
on autophagy genes. Nat Cell Biol. 6:1221–1228. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Zalckvar E, Berissi H, Mizrachy L,
Idelchuk Y, Koren I, Eisenstein M, Sabanay H, Pinkas-Kramarski R
and Kimchi A: DAP-kinase-mediated phosphorylation on the BH3 domain
of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and
induction of autophagy. EMBO Rep. 10:285–292. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Zalckvar E, Berissi H, Eisenstein M and
Kimchi A: Phosphorylation of Beclin 1 by DAP-kinase promotes
autophagy by weakening its interactions with Bcl-2 and Bcl-XL.
Autophagy. 5:720–722. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Ying H, Qu D, Liu C, Ying T, Lv J, Jin S
and Xu H: Chemoresistance is associated with Beclin-1 and PTEN
expression in epithelial ovarian cancers. Oncol Lett. 9:1759–1763.
2015.PubMed/NCBI
|
|
24
|
Won KY, Kim GY, Lim SJ, Sung JY, Kim YW,
Park YK, Lee J and Choi HS: Autophagy is related to the hedgehog
signaling pathway in human gastric adenocarcinoma: Prognostic
significance of Beclin-1 and Gli2 expression in human gastric
adenocarcinoma. Pathol Res Pract. 211:308–315. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Galadari S, Rahman A, Pallichankandy S and
Thayyullathil F: Tumor suppressive functions of ceramide: Evidence
and mechanisms. Apoptosis. 20:689–711. 2015. View Article : Google Scholar : PubMed/NCBI
|
