|
1
|
Mountzios G, Terpos E and Dimopoulos MA:
Aurora kinases as targets for cancer therapy. Cancer Treat Rev.
34:175–182. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Fu J, Bian M, Jiang Q and Zhang C: Roles
of Aurora kinases in mitosis and tumorigenesis. Mol Cancer Res.
5:1–10. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Barr AR and Gergely F: Aurora-A: The maker
and breaker of spindle poles. J Cell Sci. 120:2987–2996. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Qi W, Cooke LS, Liu X, Rimsza L, Roe DJ,
Manziolli A, Persky DO, Miller TP and Mahadevan D: Aurora inhibitor
MLN8237 in combination with docetaxel enhances apoptosis and
anti-tumor activity in mantle cell lymphoma. Biochem Pharmacol.
81:881–890. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Harrington EA, Bebbington D, Moore J,
Rasmussen RK, Ajose-Adeogun AO, Nakayama T, Graham JA, Demur C,
Hercend T, Diu-Hercend A, et al: VX-680, a potent and selective
small-molecule inhibitor of the Aurora kinases, suppresses tumor
growth in vivo. Nat Med. 10:262–267. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Keen N and Taylor S: Aurora-kinase
inhibitors as anticancer agents. Nat Rev Cancer. 4:927–936. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Katayama H, Zhou H, Li Q, Tatsuka M and
Sen S: Interaction and feedback regulation between
STK15/BTAK/Aurora-A kinase and protein phosphatase 1 through
mitotic cell division cycle. J Biol Chem. 276:46219–46224. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
He W, Zhang MG, Wang XJ, Zhong S, Shao Y,
Zhu Y and Shen ZJ: AURKA suppression induces DU145 apoptosis and
sensitizes DU145 to docetaxel treatment. Am J Transl Res.
5:359–367. 2013.PubMed/NCBI
|
|
9
|
Kaufman RJ: Stress signaling from the
lumen of the endoplasmic reticulum: Coordination of gene
transcriptional and translational controls. Genes Dev.
13:1211–1233. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Wu J and Kaufman RJ: From acute ER stress
to physiological roles of the unfolded protein response. Cell Death
Differ. 13:374–384. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Lee da H, Jung Y Jung, Koh D, Lim Y, Lee
YH and Shin SY: A synthetic chalcone,
2′-hydroxy-2,3,5′-trimethoxychalcone triggers unfolded protein
response-mediated apoptosis in breast cancer cells. Cancer Lett.
372:1–9. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Shin SY, Lee JM, Lee MS, Koh D, Jung H,
Lim Y and Lee YH: Targeting cancer cells via the reactive oxygen
species-mediated unfolded protein response with a novel synthetic
polyphenol conjugate. Clin Cancer Res. 20:4302–4313. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Calfon M, Zeng H, Urano F, Till JH,
Hubbard SR, Harding HP, Clark SG and Ron D: IRE1 couples
endoplasmic reticulum load to secretory capacity by processing the
XBP-1 mRNA. Nature. 415:92–96. 2002. View
Article : Google Scholar : PubMed/NCBI
|
|
14
|
Jiang Y, Zhang Y, Lees E and Seghezzi W:
AuroraA overexpression overrides the mitotic spindle checkpoint
triggered by nocodazole, a microtubule destabilizer. Oncogene.
22:8293–8301. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Andree HA, Reutelingsperger CP, Hauptmann
R, Hemker HC, Hermens WT and Willems GM: Binding of vascular
anticoagulant alpha (VAC alpha) to planar phospholipid bilayers. J
Biol Chem. 265:4923–4928. 1990.PubMed/NCBI
|
|
16
|
McIlwain DR, Berger T and Mak TW: Caspase
functions in cell death and disease. Cold Spring Harb Perspect
Biol. 5:a0086562013. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Rigas B and Sun Y: Induction of oxidative
stress as a mechanism of action of chemopreventive agents against
cancer. Br J Cancer. 98:1157–1160. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Schumacker PT: Reactive oxygen species in
cancer cells: Live by the sword, die by the sword. Cancer Cell.
10:175–176. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Raj L, Ide T, Gurkar AU, Foley M, Schenone
M, Li X, Tolliday NJ, Golub TR, Carr SA, Shamji AF, et al:
Selective killing of cancer cells by a small molecule targeting the
stress response to ROS. Nature. 475:231–234. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Adams DJ, Dai M, Pellegrino G, Wagner BK,
Stern AM, Shamji AF and Schreiber SL: Synthesis, cellular
evaluation, and mechanism of action of piperlongumine analogs. Proc
Natl Acad Sci USA. 109:pp. 15115–15120. 2012; View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Cui X: Reactive oxygen species: The
Achilles' heel of cancer cells? Antioxid Redox Signal.
16:1212–1214. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Kim BM, Rode AB, Han EJ, Hong IS and Hong
SH: 5-Phenylselenyl- and 5-methylselenyl-methyl-2′-deoxyuridine
induce oxidative stress, DNA damage, and caspase-2-dependent
apoptosis in cancer cells. Apoptosis. 17:200–216. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Kitamura M: The unfolded protein response
triggered by environmental factors. Semin Immunopathol. 35:259–275.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Puthalakath H, O'Reilly LA, Gunn P, Lee L,
Kelly PN, Huntington ND, Hughes PD, Michalak EM, McKimm-Breschkin
J, Motoyama N, et al: ER stress triggers apoptosis by activating
BH3-only protein Bim. Cell. 129:1337–1349. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Zinszner H, Kuroda M, Wang X, Batchvarova
N, Lightfoot RT, Remotti H, Stevens JL and Ron D: CHOP is
implicated in programmed cell death in response to impaired
function of the endoplasmic reticulum. Genes Dev. 12:982–995. 1998.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Sidrauski C and Walter P: The
transmembrane kinase Ire1p is a site-specific endonuclease that
initiates mRNA splicing in the unfolded protein response. Cell.
90:1031–1039. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Marciniak SJ, Yun CY, Oyadomari S, Novoa
I, Zhang Y, Jungreis R, Nagata K, Harding HP and Ron D: CHOP
induces death by promoting protein synthesis and oxidation in the
stressed endoplasmic reticulum. Genes Dev. 18:3066–3077. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Szegezdi E, Logue SE, Gorman AM and Samali
A: Mediators of endoplasmic reticulum stress-induced apoptosis.
EMBO Rep. 7:880–885. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Happo L, Strasser A and Cory S: BH3-only
proteins in apoptosis at a glance. J Cell Sci. 125:1081–1087. 2012.
View Article : Google Scholar : PubMed/NCBI
|
