Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
December-2017 Volume 14 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
December-2017 Volume 14 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Potential factors influencing the development of oral tongue squamous cell carcinoma in young mature patients: Lingual position of the mandibular second molar and narrow tongue space

  • Authors:
    • Yusoon Kim
    • Kohei Okuyama
    • Yasuyuki Michi
    • Yoshio Ohyama
    • Narikazu Uzawa
    • Satoshi Yamaguchi
  • View Affiliations / Copyright

    Affiliations: Section of Maxillofacial Surgery, Department of Maxillofacial and Neck Reconstruction, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113‑8549, Japan, Department of Clinical Oral Oncology, Unit of Translational Medicine, Course of Medical and Dental Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki 852‑8588, Japan
    Copyright: © Kim et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 7339-7343
    |
    Published online on: October 3, 2017
       https://doi.org/10.3892/ol.2017.7135
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The lingual position of the mandibular second molar and narrow tongue space are associated with oral tongue squamous cell carcinoma (OTSCC) development in young mature patients. The present study aimed to assess the role of the mandibular second molar position and tongue space in young mature patients with OTSCC. The medical records of 21 patients with OTSCC aged <50 years, who had an intact mandibular second molar and had undergone computed tomography (CT) imaging between April 2009 and December 2015 at the Section of Maxillofacial Surgery in Tokyo Medical and Dental University, were retrospectively examined. As controls, 21 sex‑matched patients of a similar age to the patients in the OTSCC group, and with a height and weight within 5% of those of the OTSCC group, were collected. The location of the mandibular second molar on the affected side and area of the tongue space were determined using coronal and axial CT images. Mann‑Whitney U test analysis revealed that the location of the mandibular second molar and the area of the tongue space differed significantly between young mature patients with OTSCC and the controls. The present study thus revealed that the lingual position of the mandibular second molar and the narrow tongue space may be potential factors influencing OTSCC development in young maturity.
View Figures

Figure 1

Figure 2

Figure 3

View References

1 

Lissowska J, Pilarska A, Pilarski P, Samolczyk-Wanyura D, Piekarczyk J, Bardin-Mikolłajczak A, Zatonski W, Herrero R, Munoz N and Franceschi S: Smoking, alcohol, diet, dentition and sexual practices in the epidemiology of oral cancer in Poland. Eur J Cancer Prev. 12:25–33. 2003. View Article : Google Scholar : PubMed/NCBI

2 

Fan H, Yoon KY, Kim SM, Myoung H, Lee JH and Kim MJ: Relationship between squamous cell carcinoma of the tongue and the position of dental prosthesis. J Adv Prosthodont. 7:129–137. 2015. View Article : Google Scholar : PubMed/NCBI

3 

Zafereo ME, Xu L, Dahlstrom KR, Viamonte CA, El-Naggar AK, Wei Q, Li G and Sturgis EM: Squamous cell carcinoma of the oral cavity often overexpresses p16 but is rarely driven by human papillomavirus. Oral Oncol. 56:47–53. 2016. View Article : Google Scholar : PubMed/NCBI

4 

Amagasa T, Yamashiro M and Uzawa N: Oral premalignant lesions: From a clinical perspective. Int J Clin Oncol. 16:5–14. 2011. View Article : Google Scholar : PubMed/NCBI

5 

Hougeir FG, Yiannias JA, Hinni ML, Hentz JG and el-Azhary RA: Oral metal contact allergy: A pilot study on the cause of oral squamous cell carcinoma. Int J Dermatol. 45:265–271. 2006. View Article : Google Scholar : PubMed/NCBI

6 

Siegelmann-Danieli N, Hanlon A, Ridge JA, Padmore R, Fein DA and Langer CJ: Oral tongue cancer in patients less than 45 years old: Institutional experience and comparison with older patients. J Clin Oncol. 16:745–753. 1998. View Article : Google Scholar : PubMed/NCBI

7 

Sato T: A study on effect of mechanical irritation in development and progression of tongue cancer. Kokubyo Gakkai Zasshi. 62:532–550. 1995.(In Japanese). View Article : Google Scholar : PubMed/NCBI

8 

Hilly O, Shkedy Y, Hod R, Soudry E, Mizrachi A, Hamzany Y, Bachar G and Shpitzer T: Carcinoma of the oral tongue in patients younger than 30 years: Comparison with patients older than 60 years. Oral Oncol. 49:987–990. 2013. View Article : Google Scholar : PubMed/NCBI

9 

Jones JB, Lampe HB and Cheung HW: Carcinoma of the tongue in young patients. J Otolaryngol. 18:105–108. 1989.PubMed/NCBI

10 

Garavello W, Spreafico R and Gaini RM: Oral tongue cancer in young patients: A matched analysis. Oral Oncol. 43:894–897. 2007. View Article : Google Scholar : PubMed/NCBI

11 

Park JO, Sun DI, Cho KJ, Joo YH, Yoo HJ and Kim MS: Clinical outcome of squamous cell carcinoma of the tongue in young patients: A stage-matched comparative analysis. Clin Exp Otorhinolaryngol. 3:161–165. 2010. View Article : Google Scholar : PubMed/NCBI

12 

Sarkaria JN and Harari PM: Oral tongue cancer in young adults less than 40 years of age: Rationale for aggressive therapy. Head Neck. 16:107–111. 1994. View Article : Google Scholar : PubMed/NCBI

13 

Soudry E, Preis M, Hod R, Hamzany Y, Hadar T, Bahar G, Strenov Y and Shpitzer T: Squamous cell carcinoma of the oral tongue in patients younger than 30 years: Clinicopathologic features and outcome. Clin Otolaryngol. 35:307–312. 2010. View Article : Google Scholar : PubMed/NCBI

14 

Manuel S, Raghavan SK, Pandey M and Sebastian P: Survival in patients under 45 years with squamous cell carcinoma of the oral tongue. Int J Oral Maxillofac Surg. 32:167–173. 2003. View Article : Google Scholar : PubMed/NCBI

15 

Mallet Y, Avalos N, Le Ridant AM, Gangloff P, Moriniere S, Rame JP, Poissonnet G, Makeieff M, Cosmidis A, Babin E, et al: Head and neck cancer in young people: A series of 52 SCCs of the oral tongue in patients aged 35 years or less. Acta Otolaryngol. 129:1503–1508. 2009. View Article : Google Scholar : PubMed/NCBI

16 

Popovtzer A, Shpitzer T, Bahar G, Marshak G, Ulanovski D and Feinmesser R: Squamous cell carcinoma of the oral tongue in young patients. Laryngoscope. 114:915–917. 2004. View Article : Google Scholar : PubMed/NCBI

17 

Pindborg JJ, Reichart PA and Smith CJ: Histological typing of cancer and precancer of the oral mucosa. 2nd edition. Springer-Verlag; Berlin: 1997, View Article : Google Scholar

18 

McGregor GI, Davis N and Robins RE: Squamous cell carcinoma of the tongue and lower oral cavity in patients under 40 years of age. Am J Surg. 146:88–92. 1983. View Article : Google Scholar : PubMed/NCBI

19 

Venables CW and Craft IL: Carcinoma of the tongue in early adult life. Br J Cancer. 21:645–650. 1967. View Article : Google Scholar : PubMed/NCBI

20 

Newman AN, Rice DH, Ossoff RH and Sisson GA: Carcinoma of the tongue in persons younger than 30 years of age. Arch Otolaryngol. 109:302–304. 1983. View Article : Google Scholar : PubMed/NCBI

21 

Mashberg A, Boffetta P, Winkelman R and Garfinkel L: Tobacco smoking, alcohol drinking, and cancer of the oral cavity and oropharynx among U.S. veterans. Cancer. 72:1369–1375. 1993. View Article : Google Scholar : PubMed/NCBI

22 

Boffetta P, Mashberg A, Winkelmann R and Garfinkel L: Carcinogenic effect of tobacco smoking and alcohol drinking on anatomic sites of the oral cavity and oropharynx. Int J Cancer. 52:530–533. 1992. View Article : Google Scholar : PubMed/NCBI

23 

Schwartz SM, Daling JR, Doody DR, Wipf GC, Carter JJ, Madeleine MM, Mao EJ, Fitzgibbons ED, Huang S, Beckmann AM, et al: Oral cancer risk in relation to sexual history and evidence of human papilloma virus infection. J Natl Cancer Inst. 90:1626–1636. 1998. View Article : Google Scholar : PubMed/NCBI

24 

Laronde DM, Hislop TG, Elwood JM and Rosin MP: Oral cancer: Just the facts. J Can Dent Assoc. 74:269–272. 2008.PubMed/NCBI

25 

Preston-Martin S, Henderson BE and Pike MC: Descriptive epidemiology of cancers of the upper respiratory tract in Los Angeles. Cancer. 49:2201–2207. 1982. View Article : Google Scholar : PubMed/NCBI

26 

Cox B, Taylor K and Treasure E: Trends in oral cancer by subsite in New Zealand. Eur J Cancer B Oral Oncol. 31B:113–117. 1995. View Article : Google Scholar : PubMed/NCBI

27 

Macfarlane GJ, Sharp L, Porter S and Franceschi S: Trends in survival from cancers of the oral cavity and pharynx in Scotland: A clue as to why the disease is becoming more common? Br J Cancer. 73:805–808. 1996. View Article : Google Scholar : PubMed/NCBI

28 

Jainkittivong A, Aneksuk V and Langlais RP: Oral mucosal conditions in elderly dental patients. Oral Dis. 8:218–223. 2002. View Article : Google Scholar : PubMed/NCBI

29 

Lockhart PB, Norris CM Jr and Pulliam C: Dental factors in the genesis of squamous cell carcinoma of the oral cavity. Oral Oncol. 34:133–139. 1998. View Article : Google Scholar : PubMed/NCBI

30 

Kinnebrew M, Gettleman L, Carr RF and Beazley R: Squamous cell carcinoma of the tongue in a young woman. Report of a case with etiologic considerations. Oral Surg Oral Med Oral Pathol. 58:696–698. 1984. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Kim Y, Okuyama K, Michi Y, Ohyama Y, Uzawa N and Yamaguchi S: Potential factors influencing the development of oral tongue squamous cell carcinoma in young mature patients: Lingual position of the mandibular second molar and narrow tongue space. Oncol Lett 14: 7339-7343, 2017.
APA
Kim, Y., Okuyama, K., Michi, Y., Ohyama, Y., Uzawa, N., & Yamaguchi, S. (2017). Potential factors influencing the development of oral tongue squamous cell carcinoma in young mature patients: Lingual position of the mandibular second molar and narrow tongue space. Oncology Letters, 14, 7339-7343. https://doi.org/10.3892/ol.2017.7135
MLA
Kim, Y., Okuyama, K., Michi, Y., Ohyama, Y., Uzawa, N., Yamaguchi, S."Potential factors influencing the development of oral tongue squamous cell carcinoma in young mature patients: Lingual position of the mandibular second molar and narrow tongue space". Oncology Letters 14.6 (2017): 7339-7343.
Chicago
Kim, Y., Okuyama, K., Michi, Y., Ohyama, Y., Uzawa, N., Yamaguchi, S."Potential factors influencing the development of oral tongue squamous cell carcinoma in young mature patients: Lingual position of the mandibular second molar and narrow tongue space". Oncology Letters 14, no. 6 (2017): 7339-7343. https://doi.org/10.3892/ol.2017.7135
Copy and paste a formatted citation
x
Spandidos Publications style
Kim Y, Okuyama K, Michi Y, Ohyama Y, Uzawa N and Yamaguchi S: Potential factors influencing the development of oral tongue squamous cell carcinoma in young mature patients: Lingual position of the mandibular second molar and narrow tongue space. Oncol Lett 14: 7339-7343, 2017.
APA
Kim, Y., Okuyama, K., Michi, Y., Ohyama, Y., Uzawa, N., & Yamaguchi, S. (2017). Potential factors influencing the development of oral tongue squamous cell carcinoma in young mature patients: Lingual position of the mandibular second molar and narrow tongue space. Oncology Letters, 14, 7339-7343. https://doi.org/10.3892/ol.2017.7135
MLA
Kim, Y., Okuyama, K., Michi, Y., Ohyama, Y., Uzawa, N., Yamaguchi, S."Potential factors influencing the development of oral tongue squamous cell carcinoma in young mature patients: Lingual position of the mandibular second molar and narrow tongue space". Oncology Letters 14.6 (2017): 7339-7343.
Chicago
Kim, Y., Okuyama, K., Michi, Y., Ohyama, Y., Uzawa, N., Yamaguchi, S."Potential factors influencing the development of oral tongue squamous cell carcinoma in young mature patients: Lingual position of the mandibular second molar and narrow tongue space". Oncology Letters 14, no. 6 (2017): 7339-7343. https://doi.org/10.3892/ol.2017.7135
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team