Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
December-2017 Volume 14 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
December-2017 Volume 14 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Anticancer effect of triterpenes from Ganoderma lucidum in human prostate cancer cells

  • Authors:
    • Lijun Qu
    • Sumei Li
    • Yumin Zhuo
    • Jianfan Chen
    • Xiaoping Qin
    • Guoqing Guo
  • View Affiliations / Copyright

    Affiliations: Department of Urology, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong 510630, P.R. China, Department of Anatomy, Medical College of Jinan University, Guangzhou, Guangdong 510630, P.R. China
    Copyright: © Qu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 7467-7472
    |
    Published online on: October 9, 2017
       https://doi.org/10.3892/ol.2017.7153
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Ganoderma lucidum, within the Polyporaceae family of Basidiomycota, is a popular traditional remedy medicine used in Asia to promote health and longevity. Compounds extracted from G. lucidum have revealed anticancer, antioxidant and liver protective effects. G. lucidum has been associated with prostate cancer cells. G. lucidum extracts contain numerous bioactive components; however, the exact functional monomer is unknown and the role of triterpenes from G. lucidum (GLT) in prostate cancer remain obscure. The present study investigated the effects of GLT on cell viability, migration, invasion and apoptosis in DU‑145 human prostate cancer cells. The results demonstrated that a high dose (2 mg/ml) of GLT inhibits cell viability in a dose‑ and time‑dependent manner by the regulation of matrix metalloproteases. Furthermore, GLT induced apoptosis of DU‑145 cells. In general, GLT exerts its effect on cancer cells via numerous mechanisms and may have potential therapeutic use for the prevention and treatment of cancer.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

View References

1 

Jemal A, Murray T, Samuels A, Ghafoor A, Ward E and Thun MJ: Cancer statistics, 2003. CA Cancer J Clin. 53:5–26. 2003. View Article : Google Scholar : PubMed/NCBI

2 

Taichman RS, Loberg RD, Mehra R and Pienta KJ: The evolving biology and treatment of prostate cancer. J Clin Invest. 117:2351–2361. 2007. View Article : Google Scholar : PubMed/NCBI

3 

Norgaard M, Jensen AØ, Jacobsen JB, Cetin K, Fryzek JP and Sørensen HT: Skeletal related events, bone metastasis and survival of prostate cancer: A population based cohort study in Denmark (1999 to 2007). J Urol. 184:162–167. 2010. View Article : Google Scholar : PubMed/NCBI

4 

Cheung WM, Hui WS, Chu PW, Chiu SW and Ip NY: Ganoderma extract activates MAP kinases and induces the neuronal differentiation of rat pheochromocytoma PC12 cells. FEBS Lett. 486:291–296. 2000. View Article : Google Scholar : PubMed/NCBI

5 

Wang SY, Hsu ML, Hsu HC, Tzeng CH, Lee SS, Shiao MS and Ho CK: The anti-tumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocytes. Int J Cancer. 70:699–705. 1997. View Article : Google Scholar : PubMed/NCBI

6 

Wasser SP and Weis AL: Therapeutic effects of substances occurring in higher Basidiomycetes mushrooms: a modern perspective. Crit Rev Immunol. 19:65–96. 1999.PubMed/NCBI

7 

Ji Z, Tang Q, Zhang J, Yang Y, Jia W and Pan Y: Immunomodulation of RAW264.7 macrophages by GLIS, a proteopolysaccharide from Ganoderma lucidum. J Ethnopharmacol. 112:445–450. 2007. View Article : Google Scholar : PubMed/NCBI

8 

Mizushina Y, Takahashi N, Hanashima L, Koshino H, Esumi Y, Uzawa J, Sugawara F and Sakaguchi K: Lucidenic acid O and lactone, new terpene inhibitors of eukaryotic DNA polymerases from a basidiomycete, Ganoderma lucidum. Bioorg Med Chem. 7:2047–2052. 1999. View Article : Google Scholar : PubMed/NCBI

9 

Ferreira IC, Heleno SA, Reis FS, Stojkovic D, Queiroz MJ, Vasconcelos MH and Sokovic M: Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities. Phytochemistry. 114:38–55. 2015. View Article : Google Scholar : PubMed/NCBI

10 

Lakshmi B, Ajith TA, Sheena N, Gunapalan N and Janardhanan KK: Antiperoxidative, anti-inflammatory and antimutagenic activities of ethanol extract of the mycelium of Ganoderma lucidum occurring in South India. Teratog Carcinog Mutagen. Suppl 1:S85–S97. 2003. View Article : Google Scholar

11 

Lin ZB and Zhang HN: Anti-tumor and immunoregulatory activities of Ganoderma lucidum and its possible mechanisms. Acta Pharmacol Sin. 25:1387–1395. 2004.PubMed/NCBI

12 

Pan K, Jiang Q, Liu G, Miao X and Zhong D: Optimization extraction of Ganoderma lucidum polysaccharides and its immunity and antioxidant activities. Int J Biol Macromol. 55:301–306. 2013. View Article : Google Scholar : PubMed/NCBI

13 

Zhao W, Jiang X, Deng W, Lai Y, Wu M and Zhang Z: Antioxidant activities of Ganoderma lucidum polysaccharides and their role on DNA damage in mice induced by cobalt-60 gamma-irradiation. Food Chem Toxicol. 50:303–309. 2012. View Article : Google Scholar : PubMed/NCBI

14 

Min BS, Gao JJ, Nakamura N and Hattori M: Triterpenes from the spores of Ganoderma lucidum and their cytotoxicity against meth-A and LLC tumor cells. Chem Pharm Bull (Tokyo). 48:1026–1033. 2000. View Article : Google Scholar : PubMed/NCBI

15 

Stanley G, Harvey K, Slivova V, Jiang J and Sliva D: Ganoderma lucidum suppresses angiogenesis through the inhibition of secretion of VEGF and TGF-beta1 from prostate cancer cells. Biochem Biophys Res Commun. 330:46–52. 2005. View Article : Google Scholar : PubMed/NCBI

16 

Jiang J, Slivova V, Valachovicova T, Harvey K and Sliva D: Ganoderma lucidum inhibits proliferation and induces apoptosis in human prostate cancer cells PC-3. Int J Oncol. 24:1093–1099. 2004.PubMed/NCBI

17 

Qi M, Liu Z, Shen C, Wang L, Zeng J, Wang C, Li C, Fu W, Sun Y and Han B: Overexpression of ETV4 is associated with poor prognosis in prostate cancer: Involvement of uPA/uPAR and MMPs. Tumour Biol. 36:3565–3572. 2015. View Article : Google Scholar : PubMed/NCBI

18 

Sehgal I, Forbes K and Webb MA: Reduced secretion of MMPs, plasminogen activators and TIMPS from prostate cancer cells derived by repeated metastasis. Anticancer Res. 23:39–42. 2003.PubMed/NCBI

19 

Shiao MS: Natural products of the medicinal fungus Ganoderma lucidum: Occurrence, biological activities, and pharmacological functions. Chem Rec. 3:172–180. 2003. View Article : Google Scholar : PubMed/NCBI

20 

Liu W, Wang H, Pang X, Yao W and Gao X: Characterization and antioxidant activity of two low-molecular-weight polysaccharides purified from the fruiting bodies of Ganoderma lucidum. Int J Biol Macromol. 46:451–457. 2010. View Article : Google Scholar : PubMed/NCBI

21 

Bao X, Liu C, Fang J and Li X: Structural and immunological studies of a major polysaccharide from spores of Ganoderma lucidum (Fr.) Karst. Carbohydr Res. 332:67–74. 2001. View Article : Google Scholar : PubMed/NCBI

22 

Cao QZ and Lin ZB: Ganoderma lucidum polysaccharides peptide inhibits the growth of vascular endothelial cell and the induction of VEGF in human lung cancer cell. Life Sci. 78:1457–1463. 2006. View Article : Google Scholar : PubMed/NCBI

23 

Wachtel-Galor S, Choi SW and Benzie IF: Effect of Ganoderma lucidum on human DNA is dose dependent and mediated by hydrogen peroxide. Redox Rep. 10:145–149. 2005. View Article : Google Scholar : PubMed/NCBI

24 

Mau JL, Lin HC and Chen CC: Antioxidant properties of several medicinal mushrooms. J Agric Food Chem. 50:6072–6077. 2002. View Article : Google Scholar : PubMed/NCBI

25 

Liu X, Yuan JP, Chung CK and Chen XJ: Antitumor activity of the sporoderm-broken germinating spores of Ganoderma lucidum. Cancer Lett. 182:155–161. 2002. View Article : Google Scholar : PubMed/NCBI

26 

Ruan W, Wei Y and Popovich DG: Distinct responses of cytotoxic ganoderma lucidum triterpenoids in human carcinoma cells. Phytother Res. 29:1744–1752. 2015. View Article : Google Scholar : PubMed/NCBI

27 

Li P, Deng YP, Wei XX and Xu JH: Triterpenoids from Ganoderma lucidum and their cytotoxic activities. Nat Prod Res. 27:17–22. 2013. View Article : Google Scholar : PubMed/NCBI

28 

Cheng CR, Yue QX, Wu ZY, Song XY, Tao SJ, Wu XH, Xu PP, Liu X, Guan SH and Guo DA: Cytotoxic triterpenoids from Ganoderma lucidum. Phytochemistry. 71:1579–1585. 2010. View Article : Google Scholar : PubMed/NCBI

29 

El Dine RS, El Halawany AM, Ma CM and Hattori M: Anti-HIV-1 protease activity of lanostane triterpenes from the vietnamese mushroom Ganoderma colossum. J Nat Prod. 71:1022–1026. 2008. View Article : Google Scholar : PubMed/NCBI

30 

Min BS, Nakamura N, Miyashiro H, Bae KW and Hattori M: Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 protease. Chem Pharm Bull (Tokyo). 46:1607–1612. 1998. View Article : Google Scholar : PubMed/NCBI

31 

Zhang XQ, Ip FC, Zhang DM, Chen LX, Zhang W, Li YL, Ip NY and Ye WC: Triterpenoids with neurotrophic activity from Ganoderma lucidum. Nat Prod Res. 25:1607–1613. 2011. View Article : Google Scholar : PubMed/NCBI

32 

Lee I, Seo J, Kim J, Kim H, Youn U, Lee J, Jung H, Na M, Hattori M, Min B and Bae K: Lanostane triterpenes from the fruiting bodies of Ganoderma lucidum and their inhibitory effects on adipocyte differentiation in 3T3-L1 Cells. J Nat Prod. 73:172–176. 2010. View Article : Google Scholar : PubMed/NCBI

33 

Wilasrusmee C, Kittur S, Siddiqui J, Bruch D, Wilasrusmee S and Kittur DS: In vitro immunomodulatory effects of ten commonly used herbs on murine lymphocytes. J Altern Complement Med. 8:467–475. 2002. View Article : Google Scholar : PubMed/NCBI

34 

Goldar S, Khaniani MS, Derakhshan SM and Baradaran B: Molecular mechanisms of apoptosis and roles in cancer development and treatment. Asian Pac J Cancer Prev. 16:2129–2144. 2015. View Article : Google Scholar : PubMed/NCBI

35 

Lopez J and Tait SW: Mitochondrial apoptosis: Killing cancer using the enemy within. Br J Cancer. 112:957–962. 2015. View Article : Google Scholar : PubMed/NCBI

36 

Chen D, Peng F, Cui QC, Daniel KG, Orlu S, Liu J and Dou QP: Inhibition of prostate cancer cellular proteasome activity by a pyrrolidine dithiocarbamate-copper complex is associated with suppression of proliferation and induction of apoptosis. Front Biosci. 10:2932–2939. 2005. View Article : Google Scholar : PubMed/NCBI

37 

Evan GI and Vousden KH: Proliferation, cell cycle and apoptosis in cancer. Nature. 411:342–348. 2001. View Article : Google Scholar : PubMed/NCBI

38 

Yang Y, Kaul S, Zhang D, Anantharam V and Kanthasamy AG: Suppression of caspase-3-dependent proteolytic activation of protein kinase C delta by small interfering RNA prevents MPP+-induced dopaminergic degeneration. Mol Cell Neurosci. 25:406–421. 2004. View Article : Google Scholar : PubMed/NCBI

39 

Dickens LS, Powley IR, Hughes MA and MacFarlane M: The ‘complexities’ of life and death: Death receptor signalling platforms. Exp Cell Res. 318:1269–1277. 2012. View Article : Google Scholar : PubMed/NCBI

40 

Tait SW and Green DR: Mitochondria and cell death: Outer membrane permeabilization and beyond. Nat Rev Mol Cell Biol. 11:621–632. 2010. View Article : Google Scholar : PubMed/NCBI

41 

Vogler M, Walter HS and Dyer MJS: Targeting anti-apoptotic BCL2 family proteins in haematological malignancies-from pathogenesis to treatment. Br J Haematol. 178:364–379. 2017. View Article : Google Scholar : PubMed/NCBI

42 

Ibrado AM, Huang Y, Fang G, Liu L and Bhalla K: Overexpression of Bcl-2 or Bcl-xL inhibits Ara-C-induced CPP32/Yama protease activity and apoptosis of human acute myelogenous leukemia HL-60 cells. Cancer Res. 56:4743–4748. 1996.PubMed/NCBI

43 

Lebedeva I, Rando R, Ojwang J, Cossum P and Stein CA: Bcl-xL in prostate cancer cells: Effects of overexpression and down-regulation on chemosensitivity. Cancer Res. 60:6052–6060. 2000.PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Qu L, Li S, Zhuo Y, Chen J, Qin X and Guo G: Anticancer effect of triterpenes from Ganoderma lucidum in human prostate cancer cells. Oncol Lett 14: 7467-7472, 2017.
APA
Qu, L., Li, S., Zhuo, Y., Chen, J., Qin, X., & Guo, G. (2017). Anticancer effect of triterpenes from Ganoderma lucidum in human prostate cancer cells. Oncology Letters, 14, 7467-7472. https://doi.org/10.3892/ol.2017.7153
MLA
Qu, L., Li, S., Zhuo, Y., Chen, J., Qin, X., Guo, G."Anticancer effect of triterpenes from Ganoderma lucidum in human prostate cancer cells". Oncology Letters 14.6 (2017): 7467-7472.
Chicago
Qu, L., Li, S., Zhuo, Y., Chen, J., Qin, X., Guo, G."Anticancer effect of triterpenes from Ganoderma lucidum in human prostate cancer cells". Oncology Letters 14, no. 6 (2017): 7467-7472. https://doi.org/10.3892/ol.2017.7153
Copy and paste a formatted citation
x
Spandidos Publications style
Qu L, Li S, Zhuo Y, Chen J, Qin X and Guo G: Anticancer effect of triterpenes from Ganoderma lucidum in human prostate cancer cells. Oncol Lett 14: 7467-7472, 2017.
APA
Qu, L., Li, S., Zhuo, Y., Chen, J., Qin, X., & Guo, G. (2017). Anticancer effect of triterpenes from Ganoderma lucidum in human prostate cancer cells. Oncology Letters, 14, 7467-7472. https://doi.org/10.3892/ol.2017.7153
MLA
Qu, L., Li, S., Zhuo, Y., Chen, J., Qin, X., Guo, G."Anticancer effect of triterpenes from Ganoderma lucidum in human prostate cancer cells". Oncology Letters 14.6 (2017): 7467-7472.
Chicago
Qu, L., Li, S., Zhuo, Y., Chen, J., Qin, X., Guo, G."Anticancer effect of triterpenes from Ganoderma lucidum in human prostate cancer cells". Oncology Letters 14, no. 6 (2017): 7467-7472. https://doi.org/10.3892/ol.2017.7153
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team