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Article

Stewart‑Treves syndrome: Magnetic resonance imaging data compared with pathological results from a single center

  • Authors:
    • Bin Li
    • Zhenchang Wang
  • View Affiliations / Copyright

    Affiliations: Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, P.R. China
  • Pages: 1113-1118
    |
    Published online on: November 8, 2017
       https://doi.org/10.3892/ol.2017.7363
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Abstract

The aim of the present study was to evaluate the magnetic resonance imaging (MRI) data of patients with Stewart‑Treves Syndrome (STS), and to compare them with the corresponding pathological data. A total of 4,289 cases of secondary upper limb lymphedema (LE) from a single center, including 5 female cases of STS who underwent modified‑radical post mastectomy, were included in the study. All cases were diagnosed pathologically, and by conventional and contrast‑enhanced (ce)MRI scans. A total of 43 tumor nodules (Φ ≥4 mm) were examined. According to the immunohistochemical results, the 5 cases of STS were divided into 2 types; 4 patients exhibited STS type I [angiosarcoma (AS)] and 1 patient exhibited STS type 2 [mixed lymphangiosarcoma (mLAS)]. The MRI signal intensity (SI) of all the nodules was compared with the pathological results. In the T1WI sequences, all nodules showed isointensity compared with normal muscle tissues in the same image. However, in the T2WI sequences, there were the visually recognizable differences in the SI compared with the LE tissues in the two STS types. The SI of mLAS was more markedly decreased compared with that of AS. The SI of mLAS was closer to that of normal muscle tissues compared with the SI of AS. In the ceMRI, the SI of the tumor nodules was markedly increased in the two STS types, compared with non‑enhancement imaging. Overall, MRI is a useful tool for the evaluation and diagnosis of STS. A chronic case of LE, in which MRI examination demonstrates nodules within the LE, may suggest a diagnosis of STS.
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1 

Stewart FW and Treves N: Lymphangiosarcoma in postmastectomy lymphedema; a report of six cases in elephantiasis chirurgica. Cancer. 1:64–81. 1948. View Article : Google Scholar : PubMed/NCBI

2 

Fitzpatrick PJ: Lymphangiosarcoma and breast cancer. Can J Surg. 12:172–177. 1969.PubMed/NCBI

3 

Maldonado-Fernández N, López-Espada C, Sánchez-Rodriguez J, Rodríguez-Morata A, Fernández-Quesada F, Martínez-Gámez J, Moreno-Escobar J and García-Róspide V: Síndrome de Stewart-Treves: Linfangiosarcoma en linfedema crónico posmastectomía. Angiología. 54:467–471. 2002. View Article : Google Scholar

4 

Young RJ, Brown NJ, Reed MW, Hughes D and Woll PJ: Angiosarcoma. Lancet Oncol. 11:983–991. 2010. View Article : Google Scholar : PubMed/NCBI

5 

Sordillo PP, Chapman R, Hajdu SI, Magill GB and Golbey RB: Lymphangiosarcoma. Cancer. 48:1674–1679. 1981. View Article : Google Scholar : PubMed/NCBI

6 

Woodward AH, Ivins JC and Soule EH: Lymphangiosarcoma arising in chronic lymphedematous extremities. Cancer. 30:562–572. 1972. View Article : Google Scholar : PubMed/NCBI

7 

Grobmyer SR, Daly JM, Glotzbach RE and Grobmyer AJ III: Role of surgery in the management of postmastectomy extremity angiosarcoma (Stewart-Treves syndrome). J Surg Oncol. 73:182–188. 2000. View Article : Google Scholar : PubMed/NCBI

8 

Kerchner K, Fleischer A and Yosipovitch G: Lower extremity lymphedema update: Pathophysiology, diagnosis, and treatment guidelines. J Am Acad Dermatol. 59:324–331. 2008. View Article : Google Scholar : PubMed/NCBI

9 

Borel Rinkes IH and de Jongste AB: Lymphangiosarcoma in chronic lymphedema. Reports of 3 cases and review of the literature. Acta Chir Scand. 152:227–230. 1986.PubMed/NCBI

10 

Peyron N, Dandurand M and Guillot B: Malignant tumors as complications of lymphedema. J Mal Vasc. 18:293–298. 1993.(In French). PubMed/NCBI

11 

Martin MB, Kon ND, Kawamoto EH, Myers RT and Sterchi JM: Postmastectomy angiosarcoma. Am Surg. 50:541–545. 1984.PubMed/NCBI

12 

Nascimento AF, Raut CP and Fletcher CD: Primary angiosarcoma of the breast: Clinicopathologic analysis of 49 cases, suggesting that grade is not prognostic. Am J Surg Pathol. 32:1896–1904. 2008. View Article : Google Scholar : PubMed/NCBI

13 

Futrell J and Meyers GH Jr: The regional lymphatics and cancer immunity. Ann Surg. 177:1–7. 1973. View Article : Google Scholar : PubMed/NCBI

14 

Ruocco V, Brunetti G, Puca RV and Ruocco E: The immunocompromised district: A unifying concept for lymphoedematous, herpes-infected and otherwise damaged sites. J Eur Acad Dermatol Venereol. 23:1364–1373. 2009. View Article : Google Scholar : PubMed/NCBI

15 

Ruocco V, Schwartz RA and Ruocco E: Lymphedema: An immunologically vulnerable site for development of neoplasms. J Am Acad Dermatol. 47:124–127. 2002. View Article : Google Scholar : PubMed/NCBI

16 

Ruocco V, Ruocco E, Schwartz RA and Janniger CK: Kaposi sarcoma and quinine: A potentially overlooked triggering factor in millions of Africans. J Am Acad Dermatol. 64:434–436. 2011. View Article : Google Scholar : PubMed/NCBI

17 

Yu L and Yang SJ: Lymphangiosarcoma of the vocal cord: A rare entity defined by a D2-40 immunohistochemical and ultrastructural study. J Clin Oncol. 29:e57–e61. 2011. View Article : Google Scholar : PubMed/NCBI

18 

Kahn HJ, Bailey D and Marks A: Monoclonal antibody D2-40, a new marker of lymphatic endothelium, reacts with Kaposi's sarcoma and a subset of angiosarcomas. Mod Pathol. 15:434–440. 2002. View Article : Google Scholar : PubMed/NCBI

19 

Fukunaga M: Expression of D2-40 in lymphatic endothelium of normal tissues and in vascular tumours. Histopathology. 46:396–402. 2005. View Article : Google Scholar : PubMed/NCBI

20 

Mankey CC, McHugh JB, Thomas DG and Lucas DR: Can lymphangiosarcoma be resurrected? A clinicopathological and immunohistochemical study of lymphatic differentiation in 49 angiosarcomas. Histopathology. 56:364–371. 2010. View Article : Google Scholar : PubMed/NCBI

21 

Ohsawa M, Naka N, Tomita Y, Kawamori D, Kanno H and Aozasa K: Use of immunohistochemical procedures in diagnosing angiosarcoma. Evaluation of 98 cases. Cancer. 75:2867–2874. 1995. View Article : Google Scholar : PubMed/NCBI

22 

Schindera ST, Streit M, Kaelin U, Stauffer E, Steinbach L and Anderson SE: Stewart-Treves syndrome: MR imaging of a postmastectomy upper-limb chronic lymphedema with angiosarcoma. Skeletal Radiol. 34:156–160. 2005. View Article : Google Scholar : PubMed/NCBI

23 

Nakazono T, Kudo S, Matsuo Y, Matsubayashi R, Ehara S, Narisawa H and Yonemitsu N: Angiosarcoma associated with chronic lymphedema (Stewart-Treves syndrome) of the leg: MR imaging. Skeletal Radiol. 29:413–416. 2000. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Li B and Wang Z: Stewart‑Treves syndrome: Magnetic resonance imaging data compared with pathological results from a single center. Oncol Lett 15: 1113-1118, 2018.
APA
Li, B., & Wang, Z. (2018). Stewart‑Treves syndrome: Magnetic resonance imaging data compared with pathological results from a single center. Oncology Letters, 15, 1113-1118. https://doi.org/10.3892/ol.2017.7363
MLA
Li, B., Wang, Z."Stewart‑Treves syndrome: Magnetic resonance imaging data compared with pathological results from a single center". Oncology Letters 15.1 (2018): 1113-1118.
Chicago
Li, B., Wang, Z."Stewart‑Treves syndrome: Magnetic resonance imaging data compared with pathological results from a single center". Oncology Letters 15, no. 1 (2018): 1113-1118. https://doi.org/10.3892/ol.2017.7363
Copy and paste a formatted citation
x
Spandidos Publications style
Li B and Wang Z: Stewart‑Treves syndrome: Magnetic resonance imaging data compared with pathological results from a single center. Oncol Lett 15: 1113-1118, 2018.
APA
Li, B., & Wang, Z. (2018). Stewart‑Treves syndrome: Magnetic resonance imaging data compared with pathological results from a single center. Oncology Letters, 15, 1113-1118. https://doi.org/10.3892/ol.2017.7363
MLA
Li, B., Wang, Z."Stewart‑Treves syndrome: Magnetic resonance imaging data compared with pathological results from a single center". Oncology Letters 15.1 (2018): 1113-1118.
Chicago
Li, B., Wang, Z."Stewart‑Treves syndrome: Magnetic resonance imaging data compared with pathological results from a single center". Oncology Letters 15, no. 1 (2018): 1113-1118. https://doi.org/10.3892/ol.2017.7363
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