|
1
|
Palumbo A and Anderson K: Multiple
myeloma. N Engl J Med. 364:1046–1060. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Raab MS, Podar K, Breitkreutz I,
Richardson PG and Anderson KC: Multiple myeloma. Lancet.
374:324–339. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
De Angelis R, Minicozzi P, Sant M, Dal
Maso L, Brewster DH, Osca-Gelis G, Visser O, Maynadié M,
Marcos-Gragera R, Troussard X, et al: Survival variations by
country and age for lymphoid and myeloid malignancies in Europe
2000–2007: Results of EUROCARE-5 population-based study. Eur J
Cancer. 51:2254–2268. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Lionetti M, Agnelli L, Mosca L, Fabris S,
Andronache A, Todoerti K, Ronchetti D, Deliliers GL and Neri A:
Integrative high-resolution microarray analysis of human myeloma
cell lines reveals deregulated miRNA expression associated with
allelic imbalances and gene expression profiles. Genes Chromosomes
Cancer. 48:521–531. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Calin GA, Sevignani C, Dumitru CD, Hyslop
T, Noch E, Yendamuri S, Shimizu M, Rattan S, Bullrich F, Negrini M
and Croce CM: Human microRNA genes are frequently located at
fragile sites and genomic regions involved in cancers. Proc Natl
Acad Sci USA. 101:pp. 2999–3004. 2004; View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Chen L, Li C, Zhang R, Gao X, Qu X, Zhao
M, Qiao C, Xu J and Li J: MiR-17-92 cluster microRNAs confers
tumorigenicity in multiple myeloma. Cancer Lett. 309:62–70. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Gao X, Zhang R, Qu X, Zhao M, Zhang S, Wu
H, Jianyong L and Chen L: MiR-15a, miR-16-1 and miR-17-92 cluster
expression are linked to poor prognosis in multiple myeloma. Leuk
Res. 36:1505–1509. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Sun CY, She XM, Qin Y, Chu ZB, Chen L, Ai
LS, Zhang L and Hu Y: miR-15a and miR-16 affect the angiogenesis of
multiple myeloma by targeting VEGF. Carcinogenesis. 34:426–435.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Calin GA, Dumitru CD, Shimizu M, Bichi R,
Zupo S, Noch E, Aldler H, Rattan S, Keating M, Rai K, et al:
Frequent deletions and down-regulation of micro-RNA genes miR15 and
miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci
USA. 99:pp. 15524–15529. 2002; View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Tung YT, Huang PW, Chou YC, Lai CW, Wang
HP, Ho HC, Yen CC, Tu CY, Tsai TC, Yeh DC, et al: Lung
tumorigenesis induced by human vascular endothelial growth factor
(hVEGF)-A165 overexpression in transgenic mice and amelioration of
tumor formation by miR-16. Oncotarget. 6:10222–10238. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Kang W, Tong JH, Lung RW, Dong Y, Zhao J,
Liang Q, Zhang L, Pan Y, Yang W, Pang JC, et al: Targeting of YAP1
by microRNA-15a and microRNA-16-1 exerts tumor suppressor function
in gastric adenocarcinoma. Mol Cancer. 14:522015. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Huang E, Liu R and Chu Y: miRNA-15a/16: As
tumor suppressors and more. Future Oncol. 11:2351–2363. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Hao M, Zhang L, An G, Sui W, Yu Z, Zou D,
Xu Y, Chang H and Qiu L: Suppressing miRNA-15a/−16 expression by
interleukin-6 enhances drug-resistance in myeloma cells. J Hematol
Oncol. 4:372011. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Hao M, Zhang L, An G, Meng H, Han Y, Xie
Z, Xu Y, Li C, Yu Z, Chang H and Qiu L: Bone marrow stromal cells
protect myeloma cells from bortezomib induced apoptosis by
suppressing microRNA-15a expression. Leuk Lymphoma. 52:787–794.
2011. View Article : Google Scholar
|
|
15
|
Hideshima T, Mitsiades C, Akiyama M,
Hayashi T, Chauhan D, Richardson P, Schlossman R, Podar K, Munshi
NC, Mitsiades N and Anderson KC: Molecular mechanisms mediating
antimyeloma activity of proteasome inhibitor PS-341. Blood.
101:1530–1534. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Helwak A, Kudla G, Dudnakova T and
Tollervey D: Mapping the human miRNA interactome by CLASH reveals
frequent noncanonical binding. Cell. 153:654–665. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Jang H, Choi SY, Cho EJ and Youn HD:
Cabin1 restrains p53 activity on chromatin. Nat StructMolBio.
16:910–915. 2009.
|
|
19
|
Roccaro AM, Sacco A, Thompson B, Leleu X,
Azab AK, Azab F, Runnels J, Jia X, Ngo HT, Melhem MR, et al:
MicroRNAs 15a and 16 regulate tumor proliferation in multiple
myeloma. Blood. 113:6669–6680. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Liu W, Youn HD and Liu JO:
Thapsigargin-induced apoptosis involves cabin1-MEF2-mediated
induction of Nur77. Eur J Immunol. 31:1757–1764. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Choi SY, Jang H, Roe JS, Kim ST, Cho EJ
and Youn HD: Phosphorylation and ubiquitination-dependent
degradation of CABIN1 releases p53 for transactivation upon
genotoxic stress. Nucleic Acids Res. 41:2180–2190. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Chng WJ, Glebov O, Bergsagel PL and Kuehl
WM: Genetic events in the pathogenesis of multiple myeloma. Best
Pract Res Clin Haematol. 20:571–596. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Ventura A and Jacks T: MicroRNAs and
cancer: Short RNAs go a long way. Cell. 136:586–591. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
He L, Thomson JM, Hemann MT,
Hernando-Monge E, Mu D, Goodson S, Powers S, Cordon-Cardo C, Lowe
SW, Hannon GJ and Hammond SM: A microRNA polycistron as a potential
human oncogene. Nature. 435:828–833. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Pichiorri F, Suh SS, Ladetto M, Kuehl M,
Palumbo T, Drandi D, Taccioli C, Zanesi N, Alder H, Hagan JP, et
al: MicroRNAs regulate critical genes associated with
multiplemyeloma pathogenesis. Proc Natl Acad Sci USA. 105:pp.
12885–12890. 2008; View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Misiewicz-Krzeminska I, Sarasquete ME,
Quwaider D, Krzeminski P, Ticona FV, Paíno T, Delgado M, Aires A,
Ocio EM, García-Sanz R, et al: Restoration of microRNA-214
expression reduces growth of myeloma cells through positive
regulation of P53 and inhibition of DNA replication. Haematologica.
98:640–648. 2013. View Article : Google Scholar : PubMed/NCBI
|
