Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
May-2018 Volume 15 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
May-2018 Volume 15 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Pylorus-preserving pancreaticoduodenectomy versus standard pancreaticoduodenectomy in the treatment of duodenal papilla carcinoma

  • Authors:
    • Rui Zhao
    • Yuan Chang
    • Xianqiang Wang
    • Peng Zhang
    • Cheng Zhang
    • Peilong Lian
  • View Affiliations / Copyright

    Affiliations: Department of Hepatobiliary Surgery, Qilu Hospital, Shandong University, Jinan, Shandong 250012, P.R. China, Department of Anesthesiology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, P.R. China, Department of Hepatobiliary Surgery, The People's Liberation Army General Hospital, Beijing 100853, P.R. China
    Copyright: © Zhao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 6368-6376
    |
    Published online on: March 2, 2018
       https://doi.org/10.3892/ol.2018.8156
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

It is not known whether pylorus-preserving pancreaticoduodenectomy (PPPD) is as effective as the standard pancreaticoduodenectomy (SPD) in the treatment of duodenal papilla carcinoma (DPC). A retrospective cohort trial was undertaken to compare the results of these two procedures. Clinical data, histological findings, short‑term results, survival and quality of life of all patients who had undergone surgery for primary DPC between January 2003 and February 2010 were analyzed. According to the inclusion criteria and the surgical methods, 116 patients were divided into the PPPD group (n=43) and the SPD group (n=73). There were no significant differences in various indices, including surgery duration, extent of intraoperative hemorrhage and postoperative pathological indexes. The incidence of postoperative complications, including pancreatic fistula and delayed gastric emptying, were also similar between the two groups (20.9 vs. 21.9%; P=0.900 and 11.6 vs. 5.4%; P=0.402). Long‑term survival and quality of life were identical following a median follow‑up of 45.6 months (range, 4‑144 months). Within 6 months, there was a decreased loss of appetite following the pylorus‑preserving procedure (26.9 vs. 49.3; P=0.003). The procedures were equally effective for the treatment of DPC. PPPD offers minor advantages in the early postoperative period but not in the long term.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

View References

1 

DeOliveira ML, Trivino T and de Jesus Lopes Filho G: Carcinoma of the papilla of Vater: Are endoscopic appearance and endoscopic biopsy discordant? J Gastrointest Surg. 10:1140–1143. 2006. View Article : Google Scholar : PubMed/NCBI

2 

Kim MH, Lee SK, Seo DW, Won SY, Lee SS and Min YI: Tumors of the major duodenal papilla. Gastrointest Endosc. 54:609–620. 2001. View Article : Google Scholar : PubMed/NCBI

3 

Di Giorgio A, Alfieri S, Rotondi F, Prete F, Di Miceli D, Ridolfini MP, Rosa F, Covino M and Doglietto GB: Pancreatoduodenectomy for tumors of Vater's ampulla: Report on 94 consecutive patients. World J Surg. 29:513–518. 2005. View Article : Google Scholar : PubMed/NCBI

4 

Moriya T, Kimura W, Hirai I, Mizutani M, Ma J, Kamiga M and Fuse A: Nodal involvement as an indicator of postoperative liver metastasis in carcinoma of the papilla of Vater. J Hepatobiliary Pancreat Surg. 13:549–555. 2006. View Article : Google Scholar : PubMed/NCBI

5 

Winter JM, Cameron JL, Olino K, Herman JM, de Jong MC, Hruban RH, Wolfgang CL, Eckhauser F, Edil BH, Choti MA, et al: Clinicopathologic analysis of ampullary neoplasms in 450 patients: Implications for surgical strategy and long-term prognosis. J Gastrointest Surg. 14:379–387. 2010. View Article : Google Scholar : PubMed/NCBI

6 

Alexakis N, Halloran C, Raraty M, Ghaneh P, Sutton R and Neoptolemos JP: Current standards of surgery for pancreatic cancer. Br J Surg. 91:1410–1427. 2004. View Article : Google Scholar : PubMed/NCBI

7 

Klaiber U, Probst P, Knebel P, Contin P, Diener MK, Büchler MW and Hackert T: Meta-analysis of complication rates for single-loop versus dual-loop (Roux-en-Y) with isolated pancreaticojejunostomy reconstruction after pancreaticoduodenectomy. Br J Surg. 102:331–340. 2015. View Article : Google Scholar : PubMed/NCBI

8 

Huang W, Xiong JJ, Wan MH, Szatmary P, Bharucha S, Gomatos I, Nunes QM, Xia Q, Sutton R and Liu XB: Meta-analysis of subtotal stomach-preserving pancreaticoduodenectomy vs pylorus preserving pancreaticoduodenectomy. World J Gastroenterol. 21:6361–6373. 2015. View Article : Google Scholar : PubMed/NCBI

9 

Traverso LW and Longmire WP Jr: Preservation of the pylorus in pancreaticoduodenectomy a follow-up evaluation. Ann Surg. 192:306–310. 1980. View Article : Google Scholar : PubMed/NCBI

10 

Alsaif F: Pylorus preserving pancreaticoduodenectomy for peri-ampullary carcinoma, is it a good option? Saudi J Gastroenterol. 16:75–78. 2010. View Article : Google Scholar : PubMed/NCBI

11 

Song KB, Kim SC, Hwang DW, Lee JH, Lee DJ, Lee JW, Park KM and Lee YJ: Matched case-control analysis comparing laparoscopic and open pylorus-preserving pancreaticoduodenectomy in patients with periampullary tumors. Ann Surg. 262:146–155. 2015. View Article : Google Scholar : PubMed/NCBI

12 

Diener MK, Fitzmaurice C, Schwarzer G, Seiler CM, Hüttner FJ, Antes G, Knaebel HP and Büchler MW: Pylorus-preserving pancreaticoduodenectomy (pp Whipple) versus pancreaticoduodenectomy (classic Whipple) for surgical treatment of periampullary and pancreatic carcinoma. Cochrane Database Syst Rev CD006053. 2014. View Article : Google Scholar

13 

Kawai M, Hirono S, Okada K, Sho M, Nakajima Y, Eguchi H, Nagano H, Ikoma H, Morimura R, Takeda Y, et al: Randomized controlled trial of pancreaticojejunostomy versus stapler closure of the pancreatic stump during distal pancreatectomy to reduce pancreatic fistula. Ann Surg. 264:180–187. 2016. View Article : Google Scholar : PubMed/NCBI

14 

Seiler CA, Wagner M, Bachmann T, Redaelli CA, Schmied B, Uhl W, Friess H and Büchler MW: Randomized clinical trial of pylorus-preserving duodenopancreatectomy versus classical Whipple resection-long term results. Br J Surg. 92:547–556. 2005. View Article : Google Scholar : PubMed/NCBI

15 

Tran KT, Smeenk HG, van Eijck CH, Kazemier G, Hop WC, Greve JW, Terpstra OT, Zijlstra JA, Klinkert P and Jeekel H: Pylorus preserving pancreaticoduodenectomy versus standard Whipple procedure: A prospective, randomized, multicenter analysis of 170 patients with pancreatic and periampullary tumors. Ann Surg. 240:738–745. 2004. View Article : Google Scholar : PubMed/NCBI

16 

Lin PW and Lin YJ: Prospective randomized comparison between pylorus-preserving and standard pancreaticoduodenectomy. Br J Surg. 86:603–607. 1999. View Article : Google Scholar : PubMed/NCBI

17 

Federico A, Orditura M, Cotticelli G, DE Sio I, Romano M, Gravina AG, Dallio M, Fabozzi A, Ciardiello F, Loguercio C and DE Vita F: Safety and efficacy of sorafenib in patients with advanced hepatocellular carcinoma and Child-Pugh A or B cirrhosis. Oncol Lett. 9:1628–1632. 2015. View Article : Google Scholar : PubMed/NCBI

18 

Bassi C, Dervenis C, Butturini G, Fingerhut A, Yeo C, Izbicki J, Neoptolemos J, Sarr M, Traverso W, Buchler M, et al: Postoperative pancreatic fistula: An international study group (ISGPF) definition. Surgery. 138:8–13. 2005. View Article : Google Scholar : PubMed/NCBI

19 

Klinkenbijl JH, Jeekel J, Sahmoud T, van Pel R, Couvreur ML, Veenhof CH, Arnaud JP, Gonzalez DG, de Wit LT, Hennipman A and Wils J: Adjuvant radiotherapy and 5-fluorouracil after curative resection of cancer of the pancreas and periampullary region: Phase III trial of the EORTC gastrointestinal tract cancer cooperative group. Ann Surg. 230:776–782; discussion 782–774. 1999. View Article : Google Scholar : PubMed/NCBI

20 

Hermanek P, Scheibe O, Spiessl B and Wagner G: TNM classification of malignant tumors: The new 1987 edition. Rontgenblatter. 40:2001987.(In German). PubMed/NCBI

21 

Fitzsimmons D, Kahl S, Butturini G, van Wyk M, Bornman P, Bassi C, Malfertheiner P, George SL and Johnson CD: Symptoms and quality of life in chronic pancreatitis assessed by structured interview and the EORTC QLQ-C30 and QLQ-PAN26. Am J Gastroenterol. 100:918–926. 2005. View Article : Google Scholar : PubMed/NCBI

22 

Wellner UF, Küsters S, Sick O, Busch C, Bausch D, Bronsert P, Hopt UT, Karcz KW and Keck T: Hybrid laparoscopic versus open pylorus-preserving pancreatoduodenectomy: Retrospective matched case comparison in 80 patients. Langenbecks Arch Surg. 399:849–856. 2014. View Article : Google Scholar : PubMed/NCBI

23 

Hanna MM, Tamariz L, Gadde R, Allen C, Sleeman D, Livingstone A and Yakoub D: Delayed gastric emptying after pylorus preserving pancreaticoduodenectomy-does gastrointestinal reconstruction technique matter? Am J Surg. 211:810–819. 2016. View Article : Google Scholar : PubMed/NCBI

24 

Hanna MM, Gadde R, Allen CJ, Meizoso JP, Sleeman D, Livingstone AS, Merchant N and Yakoub D: Delayed gastric emptying after pancreaticoduodenectomy. J Surg Res. 202:380–388. 2016. View Article : Google Scholar : PubMed/NCBI

25 

Walters DM, Shada AL, LaPar DJ, Adams RB and Bauer TW: A long gastrojejunostomy is associated with decreased incidence and severity of delayed gastric emptying after pancreaticoduodenectomy. Pancreas. 44:1273–1279. 2015. View Article : Google Scholar : PubMed/NCBI

26 

Sahora K, Morales-Oyarvide V, Thayer SP, Ferrone CR, Warshaw AL, Lillemoe KD and Fernández-Del Castillo C: The effect of antecolic versus retrocolic reconstruction on delayed gastric emptying after classic non-pylorus-preserving pancreaticoduodenectomy. Am J Surg. 209:1028–1035. 2015. View Article : Google Scholar : PubMed/NCBI

27 

Sakamoto Y, Hori S, Oguro S, Arita J, Kishi Y, Nara S, Esaki M, Saiura A, Shimada K, Yamanaka T and Kosuge T: Delayed gastric emptying after stapled versus hand-sewn anastomosis of duodenojejunostomy in pylorus-preserving pancreaticoduodenectomy: A randomized controlled trial. J Gastrointest Surg. 20:595–603. 2016. View Article : Google Scholar : PubMed/NCBI

28 

Lytras D, Paraskevas KI, Avgerinos C, Manes C, Touloumis Z, Paraskeva KD and Dervenis C: Therapeutic strategies for the management of delayed gastric emptying after pancreatic resection. Langenbecks Arch Surg. 392:1–12. 2007. View Article : Google Scholar : PubMed/NCBI

29 

Klein F, Jacob D, Bahra M, Pelzer U, Puhl G, Krannich A, Andreou A, Gül S and Guckelberger O: Prognostic factors for long-term survival in patients with ampullary carcinoma: The results of a 15-year observation period after pancreaticoduodenectomy. HPB Surg. 2014:9702342014. View Article : Google Scholar : PubMed/NCBI

30 

Tol JA, Brosens LA, van Dieren S, van Gulik TM, Busch OR, Besselink MG and Gouma DJ: Impact of lymph node ratio on survival in patients with pancreatic and periampullary cancer. Br J Surg. 102:237–245. 2015. View Article : Google Scholar : PubMed/NCBI

31 

Bronsert P, Kohler I, Werner M, Makowiec F, Kuesters S, Hoeppner J, Hopt UT, Keck T, Bausch D and Wellner UF: Intestinal-type of differentiation predicts favourable overall survival: Confirmatory clinicopathological analysis of 198 periampullary adenocarcinomas of pancreatic, biliary, ampullary and duodenal origin. BMC Cancer. 13:4282013. View Article : Google Scholar : PubMed/NCBI

32 

Wenger FA, Jacobi CA, Haubold K, Zieren HU and Muller JM: Gastrointestinal quality of life after duodenopancreatectomy in pancreatic carcinoma. Preliminary results of a prospective randomized study: Pancreatoduodenectomy or pylorus-preserving pancreatoduodenectomy. Chirurg. 70:1454–1459. 1999.(In German). View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Zhao R, Chang Y, Wang X, Zhang P, Zhang C and Lian P: Pylorus-preserving pancreaticoduodenectomy versus standard pancreaticoduodenectomy in the treatment of duodenal papilla carcinoma. Oncol Lett 15: 6368-6376, 2018.
APA
Zhao, R., Chang, Y., Wang, X., Zhang, P., Zhang, C., & Lian, P. (2018). Pylorus-preserving pancreaticoduodenectomy versus standard pancreaticoduodenectomy in the treatment of duodenal papilla carcinoma. Oncology Letters, 15, 6368-6376. https://doi.org/10.3892/ol.2018.8156
MLA
Zhao, R., Chang, Y., Wang, X., Zhang, P., Zhang, C., Lian, P."Pylorus-preserving pancreaticoduodenectomy versus standard pancreaticoduodenectomy in the treatment of duodenal papilla carcinoma". Oncology Letters 15.5 (2018): 6368-6376.
Chicago
Zhao, R., Chang, Y., Wang, X., Zhang, P., Zhang, C., Lian, P."Pylorus-preserving pancreaticoduodenectomy versus standard pancreaticoduodenectomy in the treatment of duodenal papilla carcinoma". Oncology Letters 15, no. 5 (2018): 6368-6376. https://doi.org/10.3892/ol.2018.8156
Copy and paste a formatted citation
x
Spandidos Publications style
Zhao R, Chang Y, Wang X, Zhang P, Zhang C and Lian P: Pylorus-preserving pancreaticoduodenectomy versus standard pancreaticoduodenectomy in the treatment of duodenal papilla carcinoma. Oncol Lett 15: 6368-6376, 2018.
APA
Zhao, R., Chang, Y., Wang, X., Zhang, P., Zhang, C., & Lian, P. (2018). Pylorus-preserving pancreaticoduodenectomy versus standard pancreaticoduodenectomy in the treatment of duodenal papilla carcinoma. Oncology Letters, 15, 6368-6376. https://doi.org/10.3892/ol.2018.8156
MLA
Zhao, R., Chang, Y., Wang, X., Zhang, P., Zhang, C., Lian, P."Pylorus-preserving pancreaticoduodenectomy versus standard pancreaticoduodenectomy in the treatment of duodenal papilla carcinoma". Oncology Letters 15.5 (2018): 6368-6376.
Chicago
Zhao, R., Chang, Y., Wang, X., Zhang, P., Zhang, C., Lian, P."Pylorus-preserving pancreaticoduodenectomy versus standard pancreaticoduodenectomy in the treatment of duodenal papilla carcinoma". Oncology Letters 15, no. 5 (2018): 6368-6376. https://doi.org/10.3892/ol.2018.8156
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team