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Article

Texture analysis of diffusion weighted imaging for the evaluation of glioma heterogeneity based on different regions of interest

  • Authors:
    • Shan Wang
    • Meng Meng
    • Xue Zhang
    • Chen Wu
    • Ru Wang
    • Jiangfen Wu
    • Muhammad Umair Sami
    • Kai Xu
  • View Affiliations / Copyright

    Affiliations: School of Medical Imaging, Xuzhou Medical University, Xuzhou, Jiangsu 221004, P.R. China, School of Medical Imaging, Guizhou Medical University, Guiyang, Guizhou 550004, P.R. China, GE Healthcare (Shanghai) Co., Ltd., Shanghai 201203, P.R. China
  • Pages: 7297-7304
    |
    Published online on: March 12, 2018
       https://doi.org/10.3892/ol.2018.8232
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Abstract

The present study aimed to explore the role of texture analysis with apparent diffusion coefficient (ADC) maps based on different regions of interest (ROI) in determining glioma grade. Thirty patients with glioma underwent diffusion-weighted imaging (DWI). ADC values were determined from the following three ROIs: i) whole tumor; ii) solid portion; and iii) peritumoral edema. Texture features were compared between high‑grade gliomas (HGGs) and low‑grade gliomas (LGGs) using the non‑parametric Wilcoxon rank‑sum test or the unpaired Student's t‑test. Receiver operating characteristic (ROC) curves were constructed to determine the optimum threshold for inhomogeneity values in discrimination of HGGs from LGGs. With a spearman rank correlation model, the aforementioned ADC inhomogeneity values were correlated with the Ki‑67 labeling index. With whole tumor ROI, inhomogeneity values proved to be significantly different between HGGs and LGGs (P<0.001). With solid portion ROI, inhomogeneity and median values showed significant difference between HGGs and LGGs (P=0.001 and P=0.043, respectively). With peritumoral edema ROI, entropy and edema volume demonstrated positive results (P=0.016, P<0.001). The whole tumor inhomogeneity parameter performed with better diagnostic accuracy (P=0.048) than selecting the solid portion ROI. The association between inhomogeneity and Ki‑67 labeling index was significantly positive in whole tumor and solid portion ROI (R=0.628, P<0.001 and R=0.470, P=0.009). Texture analysis of DWI based on different ROI can provide various significant parameters to evaluate tumor heterogeneity, which were correlated with tumor grade. Particularly, the inhomogeneity value derived from whole tumor ROI provided high diagnostic value and predicting the status of tumor proliferation.
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1 

Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW and Kleihues P: The 2007 WHO classification of tumours of the central nervous system. Acta Neuropahtol. 114:97–109. 2007. View Article : Google Scholar

2 

Skogen K, Ganeshan B, Good C, Critchley G and Miles K: Measurements of heterogeneity in gliomas on computed tomography relationship to tumour grade. J Neurooncol. 111:213–219. 2013. View Article : Google Scholar : PubMed/NCBI

3 

Weller M: Novel diagnostic and therapeutic approaches to malignant glioma. Swiss Med Wkly. 141:w132102011.PubMed/NCBI

4 

Server A, Kulle B, Gadmar OB, Josefsen R, Kumar T and Nakstad PH: Measurements of diagnostic examination performance using quantitative apparent diffusion coefficient and proton MR spectroscopic imaging in the preoperative evaluation of tumor grade in cerebral gliomas. Eur J Radiol. 80:462–470. 2011. View Article : Google Scholar : PubMed/NCBI

5 

Chenevert TL, Stegman LD, Taylor JM, Robertson PL, Greenberg HS, Rehemtulla A and Ross BD: Diffusion magnetic resonance imaging: An earlysurrogate marker of therapeutic efficacy in brain tumors. J Natl Cancer Inst. 92:2029–2036. 2000. View Article : Google Scholar : PubMed/NCBI

6 

Ellingson BM, Cloughesy TF, Zaw T, Lai A, Nghiemphu PL, Harris R, Lalezari S, Wagle N, Naeini KM, Carrillo J, et al: Functional diffusion maps (fDMs) evaluated beforeand after radiochemotherapy predict progression-free and overall survival in newly diagnosed glioblastoma. Neuro Oncol. 14:333–343. 2012. View Article : Google Scholar : PubMed/NCBI

7 

Ellingson BM, Cloughesy TF, Lai A, Nghiemphu PL, Liau LM and Pope WB: Quantitative probabilistic functional diffusion mapping in newly diagnosed glioblastoma treated with radiochemotherapy. Neuro Oncol. 15:382–390. 2013. View Article : Google Scholar : PubMed/NCBI

8 

Rowley HA, Grant PE and Roberts TP: Diffusion MR imaging. Theory and applications. Neuroimaging Clin N Am. 9:343–361. 1999.PubMed/NCBI

9 

Sugahara T, Korogi Y, Kochi M, Ikushima I, Shigematu Y, Hirai T, Okuda T, Liang L, Ge Y, Komohara Y, et al: Usefulness of diffusion-weighted MRI with echo-planar technique in the evaluation of cellularity in gliomas. J Magn Reson Imaging. 9:53–60. 1999. View Article : Google Scholar : PubMed/NCBI

10 

Ellingson BM, Malkin MG, Rand SD, Connelly JM, Quinsey C, LaViolette PS, Bedekar DP and Schmainda KM: Validation of functional diffusion maps (fDMs) as a biomarker for human glioma cellularity. J Magn Reson Imaging. 31:538–548. 2010. View Article : Google Scholar : PubMed/NCBI

11 

Nie K, Chen JH, Yu HJ, Chu Y, Nalcioglu O and Su MY: Quantitative analysis of lesion morphology and texture features for diagnostic prediction in breast MRI. Acad Radiol. 15:1513–1525. 2008. View Article : Google Scholar : PubMed/NCBI

12 

Georgiadis P, Cavouras D, Kalatzis I, Glotsos D, Athanasiadis E, Kostopoulos S, Sifaki K, Malamas M, Nikiforidis G and Solomou E: Enhancing the discrimination accuracy between metastases, gliomas and meningiomas on brain MRI by volumetric textural features and ensemble pattern recognition methods. Magn Reson Imaging. 27:120–130. 2009. View Article : Google Scholar : PubMed/NCBI

13 

Chicklore S, Goh V, Siddique M, Roy A, Marsden PK and Cook GJ: Quantifying tumour heterogeneity in 18F-FDGPET/CT imaging by texture analysis. Eur J Nucl Med Mol Imaging. 40:133–140. 2013. View Article : Google Scholar : PubMed/NCBI

14 

Assefa D, Keller H, Ménard C, Laperriere N, Ferrari RJ and Yeung I: Texture features for response monitoring of glioblastoma multiforme on T1-weighted and T2-FLAIR MR images: A preliminary investigation in terms of identification and segmentation. Med Phys. 37:1722–1736. 2010. View Article : Google Scholar : PubMed/NCBI

15 

Herlidou-Même S, Constans JM, Carsin B, Olivie D, Eliat PA, Nadal-Desbarats L, Gondry C, Le Rumeur E, Idy-Peretti I and de Certaines JD: MRI texture analysis on texture test objects, normal brain and intracranial tumors. Magn Reson Imaging. 21:989–993. 2003. View Article : Google Scholar : PubMed/NCBI

16 

Zacharaki EI, Wang S, Chawla S, Yoo Soo D, Wolf R, Melhem ER and Davatzikos C: Classification of brain tumor type and grade using MRI texture and shape in a machine learning scheme. Magn Reson Med. 62:1609–1618. 2009. View Article : Google Scholar : PubMed/NCBI

17 

Li H, Giger ML, Lan L, Brown Bancroft J, MacMahon A, Mussman M, Olopade OI and Sennett C: Computerized analysis of mammographic parenchymal patterns on a large clinical dataset of full-field digital mammograms: Robustness study with two high-risk datasets. J Digit Imaging. 25:591–598. 2012. View Article : Google Scholar : PubMed/NCBI

18 

Brown R, Zlatescu M, Sijben A, Roldan G, Easaw J, Forsyth P, Parney I, Sevick R, Yan E, Demetrick D, et al: The use of magnetic resonance imaging to noninvasively detect genetic signatures in oligodendroglioma. Clin Cancer Res. 14:2357–2362. 2008. View Article : Google Scholar : PubMed/NCBI

19 

Nilsson J, Holgersson G, Carlsson T, Henriksson R, Bergström S and Bergqvist M: Incidence trends in high-grade primary brain tumors in males and females. Oncol Lett. 13:2831–2837. 2017. View Article : Google Scholar : PubMed/NCBI

20 

Kang H, Lee HY, Lee KS and Kim JH: Imaging-based tumor treatment response evaluation: Review of conventional, new and emerging concepts. Korean J Radiol. 13:371–390. 2012. View Article : Google Scholar : PubMed/NCBI

21 

Skogen K, Schulz A, Dormagen JB, Ganeshan B, Helseth E and Server A: Diagnostic performance of texture analysis on MRI in grading cerebral gliomas. Eur J Radiol. 85:824–829. 2016. View Article : Google Scholar : PubMed/NCBI

22 

Kang Y, Choi SH, Kim YJ, Kim KG, Sohn CH, Kim JH, Yun TJ and Chang KH: Gliomas: Histogram analysis of apparent diffusion coefficient maps with standard- or high-b-value diffusion-weighted MR imaging-correlation with tumor grade. Radiology. 261:882–890. 2011. View Article : Google Scholar : PubMed/NCBI

23 

Emblem KE, Nedregaard B, Nome T, Due-Tonnessen P, Hald JK, Scheie D, Borota OC, Cvancarova M and Bjornerud A: Glioma grading by using histogram analysis of blood volume heterogeneity from MR-derived cerebral blood volume maps. Radiology. 247:808–817. 2008. View Article : Google Scholar : PubMed/NCBI

24 

Fan GG, Deng QL, Wu ZH and Guo QY: Usefulness of diffusion/perfusion-weighted MRI in patients with non-enhancing supratentorial brain gliomas: Avaluable tool to predict tumour grading? Br J Radiol. 79:652–658. 2006. View Article : Google Scholar : PubMed/NCBI

25 

Maia AC Jr, Malheiros SM, da Rocha AJ, da Silva CJ, Gabbai AA, Ferraz FA and Stávale JN: MR cerebral blood volume maps correlated with vascular endothelial growth factor expression and tumor grade in nonenhancing gliomas. AJNR Am J Neuroradiol. 26:777–783. 2005.PubMed/NCBI

26 

Ryu YJ, Choi SH, Park SJ, Yun TJ and Kim JH: Glioma: Application of whole-tumor texture analysis of diffusion-weighted imaging for the evaluation of tumor heterogeneity. PLoS One. 9:e1083352014. View Article : Google Scholar : PubMed/NCBI

27 

Davnall F, Yip CS, Ljungqvist G, Selmi M, Ng F, Sanghera B, Ganeshan B, Miles KA, Cook GJ and Goh V: Assessment of tumor heterogeneity: An emerging imaging tool for clinical practice? Insights Imaging. 3:573–589. 2012. View Article : Google Scholar : PubMed/NCBI

28 

Yang D, Korogi Y, Sugahara T, Kitajima M, Shigematsu Y, Liang L, Ushio Y and Takahashi M: Cerebral gliomas: Prospective comparison of multivoxel 2D chemical-shift protonMR spectroscopy, echoplanar perfusion and diffusion-weighted MRI. Neuroradiology. 44:656–666. 2002. View Article : Google Scholar : PubMed/NCBI

29 

Raja R, Sinha N, Saini J, Mahadevan A, Rao KN and Swaminathan A: Assessment of tissue heterogeneity using diffusion tensor and diffusion kurtosis imaging for grading gliomas. Neuroradiology. 58:1217–1231. 2016. View Article : Google Scholar : PubMed/NCBI

30 

Guzman R, Altrichter S, El-Koussy M, Gralla J, Weis J, Barth A, Seiler RW, Schroth G and Lövblad KO: Contribution of the apparent diffusion coefficient in perilesional edema for the assessment of brain tumors. J Neuroradiol. 35:224–229. 2008. View Article : Google Scholar : PubMed/NCBI

31 

Castillo M, Smith JK, Kwock L and Wilber K: Apparent diffusion coefficients in the evaluation of high-grade cerebral gliomas. Am J Neuroradiol. 22:60–64. 2001.PubMed/NCBI

32 

Guo AC, Cummings TJ, Dash RC and Provenzale JM: Lymphomas and high-grade astrocytomas: Comparison of water diffusibility and histologic characteristics. Radiology. 224:177–183.. 2002. View Article : Google Scholar : PubMed/NCBI

33 

Scholzen T and Gerdes J: The Ki-67 protein: From the known and the unknown. J Cell Physiol. 182:311–322. 2000. View Article : Google Scholar : PubMed/NCBI

34 

Kiss R, Dewitte O, Decaestecker C, Camby I, Gordower L, Delbecque K, Pasteels JL, Brotchi J and Salmon I: The combined determination of proliferative activity and cell density in the prognosis of adult patients with supratentorial high-grade astrocytic tumors. Am J Clin Pathol. 107:321–331. 1997. View Article : Google Scholar : PubMed/NCBI

35 

Brynolfsson P, Nilsson D, Henriksson R, Hauksson J and Karlsson M: ADC texture-An imaging biomarker for high-grade glioma? Med Phys. 41:1019032014. View Article : Google Scholar : PubMed/NCBI

36 

Fan GG, Deng QL, Wu ZH and Guo QY: Usefulness of diffusion/perfusion weighted MRI in patients with non-enhancing supratentorial brain gliomas: A valuable tool to predict tumour grading? Br J Radiol. 79:652–658. 2006. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Wang S, Meng M, Zhang X, Wu C, Wang R, Wu J, Sami MU and Xu K: Texture analysis of diffusion weighted imaging for the evaluation of glioma heterogeneity based on different regions of interest. Oncol Lett 15: 7297-7304, 2018.
APA
Wang, S., Meng, M., Zhang, X., Wu, C., Wang, R., Wu, J. ... Xu, K. (2018). Texture analysis of diffusion weighted imaging for the evaluation of glioma heterogeneity based on different regions of interest. Oncology Letters, 15, 7297-7304. https://doi.org/10.3892/ol.2018.8232
MLA
Wang, S., Meng, M., Zhang, X., Wu, C., Wang, R., Wu, J., Sami, M. U., Xu, K."Texture analysis of diffusion weighted imaging for the evaluation of glioma heterogeneity based on different regions of interest". Oncology Letters 15.5 (2018): 7297-7304.
Chicago
Wang, S., Meng, M., Zhang, X., Wu, C., Wang, R., Wu, J., Sami, M. U., Xu, K."Texture analysis of diffusion weighted imaging for the evaluation of glioma heterogeneity based on different regions of interest". Oncology Letters 15, no. 5 (2018): 7297-7304. https://doi.org/10.3892/ol.2018.8232
Copy and paste a formatted citation
x
Spandidos Publications style
Wang S, Meng M, Zhang X, Wu C, Wang R, Wu J, Sami MU and Xu K: Texture analysis of diffusion weighted imaging for the evaluation of glioma heterogeneity based on different regions of interest. Oncol Lett 15: 7297-7304, 2018.
APA
Wang, S., Meng, M., Zhang, X., Wu, C., Wang, R., Wu, J. ... Xu, K. (2018). Texture analysis of diffusion weighted imaging for the evaluation of glioma heterogeneity based on different regions of interest. Oncology Letters, 15, 7297-7304. https://doi.org/10.3892/ol.2018.8232
MLA
Wang, S., Meng, M., Zhang, X., Wu, C., Wang, R., Wu, J., Sami, M. U., Xu, K."Texture analysis of diffusion weighted imaging for the evaluation of glioma heterogeneity based on different regions of interest". Oncology Letters 15.5 (2018): 7297-7304.
Chicago
Wang, S., Meng, M., Zhang, X., Wu, C., Wang, R., Wu, J., Sami, M. U., Xu, K."Texture analysis of diffusion weighted imaging for the evaluation of glioma heterogeneity based on different regions of interest". Oncology Letters 15, no. 5 (2018): 7297-7304. https://doi.org/10.3892/ol.2018.8232
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