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MicroRNA‑769‑3p inhibits tumor progression in glioma by suppressing ZEB2 and inhibiting the Wnt/β‑catenin signaling pathway

  • Authors:
    • Kai Wang
    • Shasha Yang
    • Yishen Gao
    • Caihong Zhang
    • Qiangbo Sui
  • View Affiliations / Copyright

    Affiliations: Department of Neurosurgery, Weihai Central Hospital, Weihai, Shandong 264400, P.R. China, Department of Burns, Weihai Central Hospital, Weihai, Shandong 264400, P.R. China, Department of Ultrasound, Weihai Central Hospital, Weihai, Shandong 264400, P.R. China
    Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 992-1000
    |
    Published online on: November 21, 2019
       https://doi.org/10.3892/ol.2019.11135
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Abstract

Accumulating evidence suggests the crucial role of microRNAs (miRNAs) in human cancers. The present study aimed to investigate the clinical and functional roles of miR‑769‑3p in glioma, as well as the underlying molecular mechanisms. Reverse transcription‑quantitative polymerase chain reaction (RT‑qPCR) was used to determine the expression levels of miR‑769‑3p in glioma tissues and cells. Receiver operating characteristic (ROC) curve analysis was applied to calculate the diagnostic value of miR‑769‑3p. The 5‑year survival rate of patients was calculated using Kaplan‑Meier analysis and Cox regression analysis. Cell experiments were used to investigate the functional role of miR‑769‑3p in glioma. The gene target of miR‑769‑3p was predicted by TargetScan. Changes in the levels of Wnt signaling‑related proteins were measured by western blotting. miR‑769‑3p was significantly downregulated in glioma tissues and serum, as well as in glioma cell lines (P<0.001). miR‑769‑3p expression was significantly associated with the World Health Organization grade and Karnofsky performance score. The ROC curves demonstrated that serum miR‑769‑3p level reliably distinguished patients with glioma from healthy individuals. High tissue miR‑769‑3p expression predicted poor overall survival in patients with glioma (log‑rank P=0.001) and was identified as an independent prognostic factor. In addition, zinc finger E‑box binding homeobox 2 (ZEB2) was demonstrated to be a direct target of miR‑769‑3p in glioma cells using a luciferase assay. miR‑769‑3p upregulation suppressed the activity of the Wnt/β‑catenin signaling pathway in glioma cells. In conclusion, miR‑769‑3p may serve as a diagnostic and prognostic biomarker in patients with glioma and target ZEB2 to inhibit tumor progression via the Wnt/β‑catenin signaling pathway. miR‑769‑3p may be a novel therapeutic target for the treatment of glioma.
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1 

Liang J, Zhang XL, Li S, Xie S, Wang WF and Yu RT: Ubiquitin-specific protease 22 promotes the proliferation, migration and invasion of glioma cells. Cancer Biomark. 23:381–389. 2018. View Article : Google Scholar : PubMed/NCBI

2 

Zhao W, Yin CY, Jiang J, Kong W, Xu H and Zhang H: MicroRNA-153 suppresses cell invasion by targeting SNAI1 and predicts patient prognosis in glioma. Oncol Lett. 17:1189–1195. 2019.PubMed/NCBI

3 

Yang D, Yuan Y, Zhang S, Zhao K, Li F, Ren H, Zhang Z and Yu Y: Association between IL-13 Gene rs20541 polymorphism and glioma susceptibility: A meta-analysis. Oncol Res Treat. 41:14–21. 2018. View Article : Google Scholar : PubMed/NCBI

4 

Hu S, Xu L, Li L, Luo D, Zhao H, Li D and Peng B: Overexpression of lncRNA PTENP1 suppresses glioma cell proliferation and metastasis in vitro. Onco Targets Ther. 12:147–156. 2019. View Article : Google Scholar : PubMed/NCBI

5 

Zhang Z, Huang X, Li J, Fan H, Yang F, Zhang R, Yang Y, Feng S, He D, Sun W and Xin T: Interleukin 10 promotes growth and invasion of glioma cells by up-regulating KPNA 2 in vitro. J Cancer Res Ther. 15:927–932. 2019. View Article : Google Scholar : PubMed/NCBI

6 

Hao B, Chen X and Cao Y: Yes-associated protein 1 promotes the metastasis of U251 glioma cells by upregulating Jagged-1 expression and activating the Notch signal pathway. Exp Ther Med. 16:1411–1416. 2018.PubMed/NCBI

7 

Jiang YR, Du JY, Wang DD and Yang X: miRNA-130a improves cardiac function by down-regulating TNF-α expression in a rat model of heart failure. Eur Rev Med Pharmacol Sci. 22:8454–8461. 2018.PubMed/NCBI

8 

Wu YF, Ou CC, Chien PJ, Chang HY, Ko JL and Wang BY: Chidamide-induced ROS accumulation and miR-129-3p-dependent cell cycle arrest in non-small lung cancer cells. Phytomedicine. 56:94–102. 2018. View Article : Google Scholar : PubMed/NCBI

9 

Chen X and Wang A: Clinical significance of miR-195 in hepatocellular carcinoma and its biological function in tumor progression. Onco Targets Ther. 12:527–534. 2019. View Article : Google Scholar : PubMed/NCBI

10 

Huang S, Zheng S, Cheng H, Lin Y, Wen Y and Lin W: Flot2 targeted by miR-449 acts as a prognostic biomarker in glioma. Artif Cells Nanomed Biotechnol. 47:250–255. 2019. View Article : Google Scholar : PubMed/NCBI

11 

Lu GF, Geng F, Xiao Z, Chen YS, Han Y, You CY, Gong NL, Xie ZM and Pan M: MicroRNA-6807-3p promotes the tumorigenesis of glioma by targeting downstream DACH1. Brain Res. 1708:47–57. 2019. View Article : Google Scholar : PubMed/NCBI

12 

Liu F, Xiong Y, Zhao Y, Tao L, Zhang Z, Zhang H, Liu Y, Feng G, Li B, He L, et al: Identification of aberrant microRNA expression pattern in pediatric gliomas by microarray. Diagn Pathol. 8:1582013. View Article : Google Scholar : PubMed/NCBI

13 

Han C, Song Y and Lian C: MiR-769 inhibits colorectal cancer cell proliferation and invasion by targeting HEY1. Med Sci Monit. 24:9232–9239. 2018. View Article : Google Scholar : PubMed/NCBI

14 

Zhang CJ and Du HJ: Screening key miRNAs for human hepatocellular carcinoma based on miRNA-mRNA functional synergistic network. Neoplasma. 64:816–823. 2017. View Article : Google Scholar : PubMed/NCBI

15 

Ju Q, Zhao L, Gao J, Zhou L, Xu Y, Sun Y and Zhao X: Mutant p53 increases exosome-mediated transfer of miR-21-3p and miR-769-3p to promote pulmonary metastasis. Chin J Cancer Res. 31:533–546. 2019. View Article : Google Scholar : PubMed/NCBI

16 

Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001. View Article : Google Scholar : PubMed/NCBI

17 

Komori T: The 2016 WHO classification of tumours of the central nervous system: The major points of revision. Neurol Med Chir (Tokyo). 57:301–311. 2017. View Article : Google Scholar : PubMed/NCBI

18 

Zhang F, Wu A, Wang Y and Liu J: miR-490-3p functions as a tumor suppressor in glioma by inhibiting high-mobility group AT-hook 2 expression. Exp Ther Med. 18:664–670. 2019.PubMed/NCBI

19 

Ostrom QT, Bauchet L, Davis FG, Deltour I, Fisher JL, Langer CE, Pekmezci M, Schwartzbaum JA, Turner MC, Walsh KM, et al: The epidemiology of glioma in adults: A ‘state of the science’ review. Neuro Oncol. 16:896–913. 2014. View Article : Google Scholar : PubMed/NCBI

20 

Chung DS, Shin HJ and Hong YK: A new hope in immunotherapy for malignant gliomas: Adoptive T cell transfer therapy. J Immunol Res. 2014:3265452014. View Article : Google Scholar : PubMed/NCBI

21 

Waghmare I, Roebke A, Minata M, Kango-Singh M and Nakano I: Intercellular cooperation and competition in brain cancers: Lessons from Drosophila and human studies. Stem Cells Transl Med. 3:1262–1268. 2014. View Article : Google Scholar : PubMed/NCBI

22 

Lima FR, Kahn SA, Soletti RC, Biasoli D, Alves T, da Fonseca AC, Garcia C, Romao L, Brito J, Holanda-Afonso R, et al: Glioblastoma: Therapeutic challenges, what lies ahead. Biochim Biophys Acta. 1826:338–349. 2012.PubMed/NCBI

23 

Wang R, Zuo X, Wang K, Han Q, Zuo J, Ni H, Liu W, Bao H, Tu Y and Xie P: MicroRNA-485-5p attenuates cell proliferation in glioma by directly targeting paired box 3. Am J Cancer Res. 8:2507–2517. 2018.PubMed/NCBI

24 

Wang LQ, Sun W, Wang Y, Li D and Hu AM: Downregulation of plasma miR-124 expression is a predictive biomarker for prognosis of glioma. Eur Rev Med Pharmacol Sci. 23:271–276. 2019.PubMed/NCBI

25 

Qiu HJ, Lu XH, Yang SS, Weng CY, Zhang EK and Chen FC: MiR-769 promoted cell proliferation in human melanoma by suppressing GSK3B expression. Biomed Pharmacother. 82:117–123. 2016. View Article : Google Scholar : PubMed/NCBI

26 

Zhang W, Zhao W, Ge C, Li X, Yang X, Xiang Y and Sun Z: Decreased let-7b is associated with poor prognosis in glioma. Medicine (Baltimore). 98:e157842019. View Article : Google Scholar : PubMed/NCBI

27 

Epifanova E, Babaev A, Newman AG and Tarabykin V: Role of Zeb2/Sip1 in neuronal development. Brain Res. 1705:24–31. 2019. View Article : Google Scholar : PubMed/NCBI

28 

Li Y, Zhang J, Zhang W, Liu Y, Wang K, Zhang Y, Yang C, Li X, Shi J, Su L and Hu D: MicroRNA-192 regulates hypertrophic scar fibrosis by targeting SIP1. J Mol Histol. 48:357–366. 2017. View Article : Google Scholar : PubMed/NCBI

29 

Ji H, Sang M, Liu F, Ai N and Geng C: miR-124 regulates EMT based on ZEB2 target to inhibit invasion and metastasis in triple-negative breast cancer. Pathol Res Pract. 215:697–704. 2019. View Article : Google Scholar : PubMed/NCBI

30 

Li H, Xu L, Zhao L, Ma Y, Zhu Z, Liu Y and Qu X: Insulin-like growth factor-I induces epithelial to mesenchymal transition via GSK-3βand ZEB2 in the BGC-823 gastric cancer cell line. Oncol Lett. 9:143–148. 2015. View Article : Google Scholar : PubMed/NCBI

31 

Zou Y, Ouyang Q, Wei W, Yang S, Zhang Y and Yang W: FAT10 promotes the invasion and migration of breast cancer cell through stabilization of ZEB2. Biochem Biophys Res Commun. 506:563–570. 2018. View Article : Google Scholar : PubMed/NCBI

32 

Zhang X, Xu X, Ge G, Zang X, Shao M, Zou S, Zhang Y, Mao Z, Zhang J, Mao F, et al: miR498 inhibits the growth and metastasis of liver cancer by targeting ZEB2. Oncol Rep. 41:1638–1648. 2019.PubMed/NCBI

33 

Suzuki K, Kawataki T, Endo K, Miyazawa K, Kinouchi H and Saitoh M: Expression of ZEBs in gliomas is associated with invasive properties and histopathological grade. Oncol Lett. 16:1758–1764. 2018.PubMed/NCBI

34 

Qi S, Song Y, Peng Y, Wang H, Long H, Yu X, Li Z, Fang L, Wu A, Luo W, et al: ZEB2 mediates multiple pathways regulating cell proliferation, migration, invasion, and apoptosis in glioma. PLoS One. 7:e388422012. View Article : Google Scholar : PubMed/NCBI

35 

Gong X, Liao X and Huang M: LncRNA CASC7 inhibits the progression of glioma via regulating Wnt/β-catenin signaling pathway. Pathol Res Pract. 215:564–570. 2019. View Article : Google Scholar : PubMed/NCBI

36 

Wang Y, Yang Q, Cheng Y, Gao M, Kuang L and Wang C: Myosin heavy chain 10 (MYH10) gene silencing reduces cell migration and invasion in the glioma cell lines U251, T98G, and SHG44 by inhibiting the Wnt/β-catenin pathway. Med Sci Monit. 24:9110–9119. 2018. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Wang K, Yang S, Gao Y, Zhang C and Sui Q: MicroRNA‑769‑3p inhibits tumor progression in glioma by suppressing ZEB2 and inhibiting the Wnt/β‑catenin signaling pathwayCorrigendum in /10.3892/ol.2021.12489. Oncol Lett 19: 992-1000, 2020.
APA
Wang, K., Yang, S., Gao, Y., Zhang, C., & Sui, Q. (2020). MicroRNA‑769‑3p inhibits tumor progression in glioma by suppressing ZEB2 and inhibiting the Wnt/β‑catenin signaling pathwayCorrigendum in /10.3892/ol.2021.12489. Oncology Letters, 19, 992-1000. https://doi.org/10.3892/ol.2019.11135
MLA
Wang, K., Yang, S., Gao, Y., Zhang, C., Sui, Q."MicroRNA‑769‑3p inhibits tumor progression in glioma by suppressing ZEB2 and inhibiting the Wnt/β‑catenin signaling pathwayCorrigendum in /10.3892/ol.2021.12489". Oncology Letters 19.1 (2020): 992-1000.
Chicago
Wang, K., Yang, S., Gao, Y., Zhang, C., Sui, Q."MicroRNA‑769‑3p inhibits tumor progression in glioma by suppressing ZEB2 and inhibiting the Wnt/β‑catenin signaling pathwayCorrigendum in /10.3892/ol.2021.12489". Oncology Letters 19, no. 1 (2020): 992-1000. https://doi.org/10.3892/ol.2019.11135
Copy and paste a formatted citation
x
Spandidos Publications style
Wang K, Yang S, Gao Y, Zhang C and Sui Q: MicroRNA‑769‑3p inhibits tumor progression in glioma by suppressing ZEB2 and inhibiting the Wnt/β‑catenin signaling pathwayCorrigendum in /10.3892/ol.2021.12489. Oncol Lett 19: 992-1000, 2020.
APA
Wang, K., Yang, S., Gao, Y., Zhang, C., & Sui, Q. (2020). MicroRNA‑769‑3p inhibits tumor progression in glioma by suppressing ZEB2 and inhibiting the Wnt/β‑catenin signaling pathwayCorrigendum in /10.3892/ol.2021.12489. Oncology Letters, 19, 992-1000. https://doi.org/10.3892/ol.2019.11135
MLA
Wang, K., Yang, S., Gao, Y., Zhang, C., Sui, Q."MicroRNA‑769‑3p inhibits tumor progression in glioma by suppressing ZEB2 and inhibiting the Wnt/β‑catenin signaling pathwayCorrigendum in /10.3892/ol.2021.12489". Oncology Letters 19.1 (2020): 992-1000.
Chicago
Wang, K., Yang, S., Gao, Y., Zhang, C., Sui, Q."MicroRNA‑769‑3p inhibits tumor progression in glioma by suppressing ZEB2 and inhibiting the Wnt/β‑catenin signaling pathwayCorrigendum in /10.3892/ol.2021.12489". Oncology Letters 19, no. 1 (2020): 992-1000. https://doi.org/10.3892/ol.2019.11135
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