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Article Open Access

Primary testicular lymphoma: A SEER analysis of 1,169 cases

  • Authors:
    • Haitao Xu
    • Fusheng Yao
  • View Affiliations / Copyright

    Affiliations: Department of Hematology, Anqing Municipal Hospital, Anqing, Anhui 246003, P.R. China
    Copyright: © Xu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 3113-3124
    |
    Published online on: January 21, 2019
       https://doi.org/10.3892/ol.2019.9953
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Abstract

Primary testicular lymphoma (PTL) is a rare lymphoid malignancy. The present retrospective study aimed to investigate the demographic characteristics and survival of patients with PTL, as well as the associated prognostic factors, using a population‑based database. All adults diagnosed with PTL in the Surveillance, Epidemiology, and End Results database were identified between 1973 and 2013. The Kaplan‑Meier method was used to estimate cause‑specific survival (CSS). Log‑rank test or multivariate Cox regression model was used to assess the influence of demographic and clinical parameters on CSS. A total of 1,169 patients with PTL were identified from the database, and the median age was 70 years. The predominant histological subtype was diffuse large B‑cell lymphoma, which affected 82.9% (970/1,169) of patients, and 68.6% (802/1,169) of patients had early stage disease (stages I‑II). Patients >70 years, those diagnosed at the earlier time period, or those who had advanced‑stage symptoms had the worst 5‑year CSS rates; however, treatment with rituximab significantly improved the 5‑year CSS. In conclusion, this retrospective study presented data from the largest cohort of patients with PTL and described the effects of rituximab on the CSS of patients with PTL.
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Copy and paste a formatted citation
Spandidos Publications style
Xu H and Yao F: Primary testicular lymphoma: A SEER analysis of 1,169 cases. Oncol Lett 17: 3113-3124, 2019.
APA
Xu, H., & Yao, F. (2019). Primary testicular lymphoma: A SEER analysis of 1,169 cases. Oncology Letters, 17, 3113-3124. https://doi.org/10.3892/ol.2019.9953
MLA
Xu, H., Yao, F."Primary testicular lymphoma: A SEER analysis of 1,169 cases". Oncology Letters 17.3 (2019): 3113-3124.
Chicago
Xu, H., Yao, F."Primary testicular lymphoma: A SEER analysis of 1,169 cases". Oncology Letters 17, no. 3 (2019): 3113-3124. https://doi.org/10.3892/ol.2019.9953
Copy and paste a formatted citation
x
Spandidos Publications style
Xu H and Yao F: Primary testicular lymphoma: A SEER analysis of 1,169 cases. Oncol Lett 17: 3113-3124, 2019.
APA
Xu, H., & Yao, F. (2019). Primary testicular lymphoma: A SEER analysis of 1,169 cases. Oncology Letters, 17, 3113-3124. https://doi.org/10.3892/ol.2019.9953
MLA
Xu, H., Yao, F."Primary testicular lymphoma: A SEER analysis of 1,169 cases". Oncology Letters 17.3 (2019): 3113-3124.
Chicago
Xu, H., Yao, F."Primary testicular lymphoma: A SEER analysis of 1,169 cases". Oncology Letters 17, no. 3 (2019): 3113-3124. https://doi.org/10.3892/ol.2019.9953
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