Open Access

Primary testicular lymphoma: A SEER analysis of 1,169 cases

  • Authors:
    • Haitao Xu
    • Fusheng Yao
  • View Affiliations

  • Published online on: January 21, 2019     https://doi.org/10.3892/ol.2019.9953
  • Pages: 3113-3124
  • Copyright: © Xu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Primary testicular lymphoma (PTL) is a rare lymphoid malignancy. The present retrospective study aimed to investigate the demographic characteristics and survival of patients with PTL, as well as the associated prognostic factors, using a population‑based database. All adults diagnosed with PTL in the Surveillance, Epidemiology, and End Results database were identified between 1973 and 2013. The Kaplan‑Meier method was used to estimate cause‑specific survival (CSS). Log‑rank test or multivariate Cox regression model was used to assess the influence of demographic and clinical parameters on CSS. A total of 1,169 patients with PTL were identified from the database, and the median age was 70 years. The predominant histological subtype was diffuse large B‑cell lymphoma, which affected 82.9% (970/1,169) of patients, and 68.6% (802/1,169) of patients had early stage disease (stages I‑II). Patients >70 years, those diagnosed at the earlier time period, or those who had advanced‑stage symptoms had the worst 5‑year CSS rates; however, treatment with rituximab significantly improved the 5‑year CSS. In conclusion, this retrospective study presented data from the largest cohort of patients with PTL and described the effects of rituximab on the CSS of patients with PTL.
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March-2019
Volume 17 Issue 3

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Xu H and Xu H: Primary testicular lymphoma: A SEER analysis of 1,169 cases. Oncol Lett 17: 3113-3124, 2019
APA
Xu, H., & Xu, H. (2019). Primary testicular lymphoma: A SEER analysis of 1,169 cases. Oncology Letters, 17, 3113-3124. https://doi.org/10.3892/ol.2019.9953
MLA
Xu, H., Yao, F."Primary testicular lymphoma: A SEER analysis of 1,169 cases". Oncology Letters 17.3 (2019): 3113-3124.
Chicago
Xu, H., Yao, F."Primary testicular lymphoma: A SEER analysis of 1,169 cases". Oncology Letters 17, no. 3 (2019): 3113-3124. https://doi.org/10.3892/ol.2019.9953