Open Access

Effects of different preoperative biliary drainage methods for resected malignant obstruction jaundice on the incidence rate of implantation metastasis: A meta‑analysis

  • Authors:
    • Gang Yang
    • Yongfu Xiong
    • Ji Sun
    • Tao Tang
    • Weinan Li
    • Guan Wang
    • Jingdong Li
  • View Affiliations

  • Published online on: June 24, 2020     https://doi.org/10.3892/ol.2020.11767
  • Pages: 2217-2224
  • Copyright: © Yang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

The aim of the present study was to compare the effects of percutaneous transhepatic biliary drainage (PTBD) and endoscopic biliary drainage (EBD) for resected malignant obstruction jaundice (MOJ) on the incidence rate of implantation metastasis. Databases including PubMed, EMbase, Web of Science and Cochrane Library were utilized. With reference to literature reported until January 2019, controlled clinical trials were designed to compare the effects of PTBD and EBD for MOJ on the incidence rate of implantation metastasis. Subsequently, odds ratio (OR) with 95% confidence interval (CI) was calculated with Review Manager 5.3.0 software. A total of 10 studies were enrolled in this meta‑analysis, including 1,085 cases in the PTBD group and 1,379 cases in the EBD group. The results revealed that there was a significant difference in the incidence rate of implantation metastasis between the PTBD group and EBD group (OR=0.35, 95% CI: 0.23‑0.53, P<0.00001). Subgroup analysis revealed that the incidence rates of both catheter‑related implantation metastasis and peritoneal metastasis were lower in the EBD group (OR=0.23, 95% CI: 0.12‑0.44, P<0.00001; OR=0.47, 95% CI: 0.31‑0.74, P=0.0008, respectively), and the advantage of EBD was demonstrated in perihilar cholangiocarcinoma, distal cholangiocarcinoma and pancreatic carcinoma (OR=0.35, 95% CI: 0.17‑0.74, P=0.006; OR=0.32, 95% CI: 0.17‑0.60, P=0.0005; OR=0.27, 95% CI: 0.19‑0.40, P<0.00001, respectively). In conclusion, this meta‑analysis revealed the appropriate choice of preoperative biliary drainage for resected MOJ. The application of EBD reduced the incidence rate of implantation metastasis, however more evidence is required from future studies, to confirm the results.

Related Articles

Journal Cover

September-2020
Volume 20 Issue 3

Print ISSN: 1792-1074
Online ISSN:1792-1082

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Yang G, Xiong Y, Sun J, Tang T, Li W, Wang G and Li J: Effects of different preoperative biliary drainage methods for resected malignant obstruction jaundice on the incidence rate of implantation metastasis: A meta‑analysis. Oncol Lett 20: 2217-2224, 2020
APA
Yang, G., Xiong, Y., Sun, J., Tang, T., Li, W., Wang, G., & Li, J. (2020). Effects of different preoperative biliary drainage methods for resected malignant obstruction jaundice on the incidence rate of implantation metastasis: A meta‑analysis. Oncology Letters, 20, 2217-2224. https://doi.org/10.3892/ol.2020.11767
MLA
Yang, G., Xiong, Y., Sun, J., Tang, T., Li, W., Wang, G., Li, J."Effects of different preoperative biliary drainage methods for resected malignant obstruction jaundice on the incidence rate of implantation metastasis: A meta‑analysis". Oncology Letters 20.3 (2020): 2217-2224.
Chicago
Yang, G., Xiong, Y., Sun, J., Tang, T., Li, W., Wang, G., Li, J."Effects of different preoperative biliary drainage methods for resected malignant obstruction jaundice on the incidence rate of implantation metastasis: A meta‑analysis". Oncology Letters 20, no. 3 (2020): 2217-2224. https://doi.org/10.3892/ol.2020.11767