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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2020 Volume 20 Issue 3

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Timing of breast cancer surgery during the menstrual cycle‑is there an optimal time of the month? (Review)

Sarah M. Bernhardt, Pallave Dasari, David Walsh, Amanda R. Townsend, Timothy J. Price, Wendy V. Ingman
Pages: 2045-2057
Published online on: 24 June 2020

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Review Open Access

Cervical cancer in low and middle‑income countries (Review)

Rodney Hull, Mzwandile Mbele, Tshepiso Makhafola, Chindo Hicks, Shao‑Ming Wang, Rui Manuel Reis, Ravi Mehrotra, Zilungile Mkhize‑Kwitshana, Gibson Kibiki, David O. Bates, Zodwa Dlamini
Pages: 2058-2074
Published online on: 19 June 2020

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Review Open Access

Immune disorder in endometrial cancer: Immunosuppressive microenvironment, mechanisms of immune evasion and immunotherapy (Review)

Lei Zhan, Xiaojing Liu, Jing Zhang, Yunxia Cao, Bing Wei
Pages: 2075-2090
Published online on: 25 June 2020

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Review Open Access

Implications of lipid droplets in lung cancer: Associations with drug resistance (Review)

Chunlai Jin, Peng Yuan
Pages: 2091-2104
Published online on: 24 June 2020

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Article Open Access

Konjac glucomannan reverses multi‑drug resistance of HepG2/5‑FU cells by suppressing AKT signaling and increasing p53 expression

Bin Chen, Xin Xu, Ke Zheng, Ling Liu, Yijun Yu, Ying Xin
Pages: 2105-2112
Published online on: 01 July 2020

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Article Open Access

Increase in CD4+FOXP3+ regulatory T cell number and upregulation of the HGF/c‑Met signaling pathway during the liver metastasis of colorectal cancer

Xiaoming Huang, Zexian Chen, Nanrong Zhang, Caiyan Zhu, Xutao Lin, Jiandong Yu, Zhiping Chen, Ping Lan, Yunle Wan
Pages: 2113-2118
Published online on: 26 June 2020

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Article Open Access

Effect of KRAS and NRAS mutations on the prognosis of patients with synchronous metastatic colorectal cancer presenting with liver‑only and lung‑only metastases

Shih‑Chang Chuang, Ching‑Wen Huang, Yi‑Ting Chen, Cheng‑Jen Ma, Hsiang‑Lin Tsai, Tsung‑Kun Chang, Wei‑Chih Su, Wen‑Hung Hsu, Chao‑Hung Kuo, Jaw‑Yuan Wang
Pages: 2119-2130
Published online on: 01 July 2020

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Article Open Access

Regorafenib treatment outcome for Taiwanese patients with metastatic gastrointestinal stromal tumors after failure of imatinib and sunitinib: A prospective, non‑randomized, single‑center study

Chia‑Hsiang Hu, Chun‑Nan Yeh, Jen‑Shi Chen, Chun‑Yi Tsai, Shang‑Yu Wang, Chi‑Tung Cheng, Ta‑Sen Yeh
Pages: 2131-2142
Published online on: 19 June 2020

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Article Open Access

Prognostic and predictive value of monocarboxylate transporter 4 in patients with breast cancer

Sheng Xiao, Hongjia Zhu, Yujun Shi, Zhenru Wu, Hegang Wu, Mingjun Xie
Pages: 2143-2152
Published online on: 25 June 2020

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Article Open Access

Relationship between the immunohistological examination and fluorescence visualization of oral squamous cell carcinoma

Keisuke Sugahara, Yu Koyama, Masahide Koyachi, Satoru Matsunaga, Kento Odaka, Kei Kitamura, Kei Nakajima, Kenichi Matsuzaka, Shinichi Abe, Akira Katakura
Pages: 2153-2160
Published online on: 24 June 2020

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Article Open Access

Interferon‑γ induced PD‑L1 expression and soluble PD‑L1 production in gastric cancer

Yushi Imai, Tetsuhiro Chiba, Takayuki Kondo, Hiroaki Kanzaki, Kengo  Kanayama, Junjie  Ao, Ryuta Kojima, Yuko Kusakabe, Masato  Nakamura, Tomoko  Saito, Ryo Nakagawa, Eiichiro Suzuki, Shingo Nakamoto, Ryosuke  Muroyama, Akinobu Tawada, Tomoaki Matsumura, Tomoo  Nakagawa, Jun Kato, Ai Kotani, Hisahiro Matsubara, Naoya Kato
Pages: 2161-2168
Published online on: 19 June 2020

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Article Open Access

Structure identification, antitumor activity and mechanisms of a novel polysaccharide from Ramaria flaccida (Fr.) Quél

Mingming Dong, Yiling Hou, Xiang Ding
Pages: 2169-2182
Published online on: 19 June 2020

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Article Open Access

LncRNA MEG3 inhibits non‑small cell lung cancer via interaction with DKC1 protein

Zhi Yang, Zitong Wang, Yong Duan
Pages: 2183-2190
Published online on: 24 June 2020

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Article Open Access

Knockdown of m6A methyltransferase METTL3 in gastric cancer cells results in suppression of cell proliferation

Li Jiang, Ting Chen, Li Xiong, Ji‑Hao Xu, Ai‑Yu Gong, Bin Dai, Ganlin Wu, Kenny Zhu, Eugene Lu, Nicholas William Mathy, Xian‑Ming Chen
Pages: 2191-2198
Published online on: 01 July 2020

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Article Open Access

Circular RNA profiling in plasma exosomes from patients with gastric cancer

Min Rao, Yonggang Zhu, Lingzhi Qi, Feng Hu, Pujun Gao
Pages: 2199-2208
Published online on: 01 July 2020

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Article Open Access

Limb‑bud and heart as a novel biomarker for gastric intestinal type adenocarcinoma

Shu‑Sheng Wu, Jian Chen, Ying Yan, Hui‑Qin Luo, Wen‑Ju Chen, Yi‑Fu He
Pages: 2209-2216
Published online on: 25 June 2020

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Article Open Access

Effects of different preoperative biliary drainage methods for resected malignant obstruction jaundice on the incidence rate of implantation metastasis: A meta‑analysis

Gang Yang, Yongfu Xiong, Ji Sun, Tao Tang, Weinan Li, Guan Wang, Jingdong Li
Pages: 2217-2224
Published online on: 24 June 2020

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Article Open Access

MicroRNA‑101 suppresses colorectal cancer progression by negative regulation of Rap1b

Zhiyuan Zhou, Hang Xu, Yantao Duan, Bin Liu
Pages: 2225-2231
Published online on: 01 July 2020

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Article Open Access

Value of shear wave elastography in the diagnosis and evaluation of cervical cancer

Bing Fu, Hong Zhang, Zhen‑Wei Song, Ji‑Xiang Lu, Shi‑Hui Wu, Jie Li
Pages: 2232-2238
Published online on: 19 June 2020

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Article Open Access

miR129‑1 regulates protein phosphatase 1D protein expression under hypoxic conditions in non‑small cell lung cancer cells harboring a TP53 mutation

Hong‑Lei Yin, Hong‑Wei Xu, Qing‑Yan Lin
Pages: 2239-2247
Published online on: 26 June 2020

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Article Open Access

Stanniocalcin 1 is a prognostic biomarker in glioma

Weijian Luo, Dong Chen, Hao Wang, Jiliang Hu
Pages: 2248-2256
Published online on: 01 July 2020

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Article Open Access

Lenvatinib prolongs the progression‑free survival time of patients with intermediate‑stage hepatocellular carcinoma refractory to transarterial chemoembolization: A multicenter cohort study using data mining analysis

Shigeo Shimose, Takumi Kawaguchi, Masatoshi Tanaka, Hideki Iwamoto, Ken Miyazaki, Etsuko Moriyama, Hiroyuki Suzuki, Takashi Niizeki, Tomotake Shirono, Masahito Nakano, Hideya Suga, Taizo Yamaguchi, Yoshinori Yokokura, Kazunori Noguchi, Hironori Koga, Takuji Torimura
Pages: 2257-2265
Published online on: 19 June 2020

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Article Open Access

Patients with advanced non‑small cell lung cancer with EGFR mutations in addition to complex mutations treated with osimertinib have a poor clinical outcome: A real‑world data analysis

Nijia Chang, Jingjing Duan, Lingxiong Wang, Zhouhuan Dong, Zhefeng Liu
Pages: 2266-2272
Published online on: 01 July 2020

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Article Open Access

Mutation analysis and genomic imbalances of cells found in effusion fluids from patients with ovarian cancer

Marta Brunetti, Ioannis Panagopoulos, Ilyá Kostolomov, Ben Davidson, Sverre Heim, Francesca Micci
Pages: 2273-2279
Published online on: 26 June 2020

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Article Open Access

Use of peripheral blood transcriptomic biomarkers to distinguish high‑grade cervical squamous intraepithelial lesions from low‑grade lesions

Cunhua Zou, Yali Lyu, Jing Jiang, Yuan Cao, Min Wang, Changmei Sang, Ruirui  Zhang, Haifeng Li, Choong‑Chin Liew, Changming Cheng, Shuping Zhao
Pages: 2280-2290
Published online on: 26 June 2020

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Article Open Access

Mechanistic studies of cytotoxic activity of the mesoionic compound MIH 2.4Bl in MCF‑7 breast cancer cells

Luciana Amaral de Mascena Costa, Dipti Debnath, Ashlyn C. Harmon, Silvany de Sousa Araújo, Helivaldo Diógenes da Silva Souza, Petrônio Filgueiras de Athayde Filho, Aurea Wischral, Manoel Adrião Gomes Filho, J. Michael Mathis
Pages: 2291-2301
Published online on: 19 June 2020

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Article Open Access

Potential five‑mRNA signature model for the prediction of prognosis in patients with papillary thyroid carcinoma

Lin‑Kun Zhong, Xiao‑Xiong Gan, Xing‑Yan Deng, Fei Shen, Jian‑Hua Feng, Wen‑Song Cai, Qiong‑Yao Liu, Jian‑Hang Miao, Bing‑Xing Zheng, Bo Xu
Pages: 2302-2310
Published online on: 26 June 2020

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Article Open Access

Small RNA profiles of HTLV‑1 asymptomatic carriers with monoclonal and polyclonal rearrangement of the T‑cell antigen receptor γ‑chain using massively parallel sequencing: A pilot study

Daniela Raguer Valadão de Souza, Rodrigo Pessôa, Andrezza Nascimento, Youko Nukui, Juliana Pereira, Jorge Casseb, Augusto César Penalva de Oliveira, Alberto José da Silva Duarte, Patricia Bianca Clissa, Sabri Saeed Sanabani
Pages: 2311-2321
Published online on: 01 July 2020

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Article Open Access

Effectiveness of fibrin sealant as a hemostatic technique in accelerating endoscopic submucosal dissection-induced ulcer healing and preventing stricture in the esophagus: A retrospective study

Jing Wang, Shao-Lei Li, Nan Wu, Qi Wu
Pages: 2322-2330
Published online on: 25 June 2020

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Article Open Access

γ‑H2AX as a potential indicator of radiosensitivity in colorectal cancer cells

Satoshi Kawashima, Nao Kawaguchi, Kohei Taniguchi, Keitaro Tashiro, Kazumasa Komura, Tomohito Tanaka, Yosuke Inomata, Yoshiro Imai, Ryo Tanaka, Masashi Yamamoto, Yoshihiro Inoue, Sang‑Woong Lee, Masaru Kawai, Keitaro Tanaka, Junji Okuda, Kazuhisa Uchiyama
Pages: 2331-2337
Published online on: 26 June 2020

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Article Open Access

CAF‑1/p150 promotes cell proliferation, migration, invasion and predicts a poor prognosis in patients with cervical cancer

Shu Yang, Qian Long, Min Chen, Xiao Liu , Hang Zhou
Pages: 2338-2346
Published online on: 25 June 2020

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Case Report Open Access

Primary intradural extramedullary Ewing sarcoma: A case report and literature review

Yuya Izubuchi, Hideaki Nakajima, Kazuya Honjoh, Yoshiaki Imamura, Takayuki Nojima, Akihiko Matsumine
Pages: 2347-2355
Published online on: 26 June 2020

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Article Open Access

High expression of GPNMB indicates an unfavorable prognosis in glioma: Combination of data from the GEO and CGGA databases and validation in tissue microarray

Xiao Feng, Lina Zhang, Shanbao Ke, Tao Liu, Liuwei  Hao, Pan Zhao, Wenzhi Tu, Shundong Cang
Pages: 2356-2368
Published online on: 26 June 2020

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Article Open Access

Synthetic MUC1 breast cancer vaccine containing a Toll‑like receptor 7 agonist exerts antitumor effects

Yu Liu, Li Tang, Ningning Gao, Yuwen Diao, Jingjing Zhong, Yongqiang Deng, Zhulin Wang, Guangyi Jin, Xiaodong Wang
Pages: 2369-2377
Published online on: 19 June 2020

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Article Open Access

Bioinformatics analysis of aberrantly expressed exosomal lncRNAs in oral squamous cell carcinoma (CAL‑27 vs. oral epithelial) cells

Jiajia Jin, Zixiao Huang, Xiaoyan Lu, Shengrong Wu, Mei'e Jia, Xin Li, Zhiyong Li, Xiangyi He
Pages: 2378-2386
Published online on: 24 June 2020

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Article Open Access

PAK6 promotes cervical cancer progression through activation of the Wnt/β‑catenin signaling pathway

Qin Yang, Yingchao Zhao, Yeshan Chen, Yu Chang, Ai Huang, Tie Xu, Guiling Li, Gang Wu
Pages: 2387-2395
Published online on: 01 July 2020

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Article Open Access

Identification of a five‑gene signature for predicting the progression and prognosis of stage I endometrial carcinoma

Jia Bian, Yuzi Xu, Fei Wu, Qiangwei Pan, Yunlong Liu
Pages: 2396-2410
Published online on: 01 July 2020

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Article Open Access

Downregulation of microRNA‑126 is inversely correlated with insulin receptor substrate‑1 protein expression in colorectal cancer and is associated with advanced stages of disease

Shicai Ye, Caiyuan Yu, Guixia Zhang, Feixiong Shi, Yongze  Chen, Jianyun Yang, Weiyun Wu, Yu Zhou
Pages: 2411-2419
Published online on: 01 July 2020

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Article Open Access

An optimal prognostic model based on gene expression for clear cell renal cell carcinoma

Dan Xu, Wantai Dang, Shaoqing Wang, Bo Hu, Lianghong Yin, Baozhang Guan
Pages: 2420-2434
Published online on: 26 June 2020

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Article Open Access

DNA mismatch repair is not disrupted in stage 0 colorectal cancer resected using endoscopic submucosal dissection

Tomohiro Sugiyama, Moriya Iwaizumi, Masanao Kaneko, Shinya Tani, Mihoko Yamade, Yasushi Hamaya, Takahisa Furuta, Hiroaki Miyajima, Satoshi Osawa, Satoshi Baba, Masato Maekawa, Ken Sugimoto
Pages: 2435-2441
Published online on: 01 July 2020

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Article Open Access

Prognostic potential of lncRNA RHPN1-AS1 in glioma

Yong Wu, Wuting Wei, Linjun Tang, Liangwei Wang
Pages: 2442-2446
Published online on: 25 June 2020

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Article Open Access

miR‑429 inhibits osteosarcoma progression by targeting HOXA9 through suppressing Wnt/β‑catenin signaling pathway

Liangzhi Sun, Libo Wang, Suxian Luan, Yanzhou Jiang, Qiang Wang
Pages: 2447-2455
Published online on: 24 June 2020

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Article Open Access

Diagnostic value and prognostic significance of LI‑cadherin and miR‑378e in colorectal cancer

Xujie Wang, Zhihua Li, Jixin Fu, Weiwei Xu, Zongxian Li
Pages: 2456-2464
Published online on: 19 June 2020

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Case Report

Clinical management of extrapleural septal solitary fibrous tumor: A case report

Michele Cavaliere, Eva Piro, Massimo Mascolo, Claudio Di Nola, Salvatore Allosso, Antonella M. Di Lullo, Gaetano Motta, Maurizio Iengo, Elena Cantone
Pages: 2465-2468
Published online on: 30 June 2020

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Article

Biomarker phenotyping drives clinical management in axillary sentinel node: A retrospective study on women with primary breast cancer in 2002

Sergio Diotaiuti, Simona De Summa, Rosanna  Altieri, Caterina  Dantona, Stefania  Tommasi, Maria  Di Gennaro, Giuseppe  Rubini, Maria   Irene Pastena, Antonella  Argentiero, Francesco   Alfredo Zito, Nicola  Silvestris, Angelo   Virgilio Paradiso
Pages: 2469-2476
Published online on: 01 July 2020

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Article

ERK‑mediated negative feedback regulation of oncogenic EGFRvIII in glioblastoma cells

Ratna Dini Haryuni, Tomohiro Tanaka, Yue Zhou, Satoru Yokoyama, Hiroaki Sakurai
Pages: 2477-2482
Published online on: 19 June 2020

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Article

Enhancement of piperlongumine chemosensitivity by silencing heme oxygenase‑1 expression in cholangiocarcinoma cell lines

Chutima Talabnin, Krajang Talabnin, Sopit Wongkham
Pages: 2483-2492
Published online on: 26 June 2020

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Article

Enhanced therapeutic effect of transcatheter arterial chemoembolization combined with radioactive I‑125 seed implantation on liver cancer

Wenbao Liu, Nanguang Xiu, Jinwei Zhao, Lianhao Zhao
Pages: 2493-2498
Published online on: 24 June 2020

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Article

ANGPTL4 overexpression is associated with progression and poor prognosis in breast cancer

Jing Zhao, Juntian Liu, Nan Wu, Hailian Zhang, Shichao Zhang, Lijuan Li, Meng Wang
Pages: 2499-2505
Published online on: 24 June 2020

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Article Open Access

Genistein inhibits lung cancer cell stem‑like characteristics by modulating MnSOD and FoxM1 expression Retraction in /10.3892/ol.2025.15097

Zhimin Fu, Xiaocheng Cao, Lihua Liu, Xiaozheng Cao, Yinghong Cui, Xiang Li, Meifang Quan, Kaiqun Ren, A Chen, Chang Xu, Yebei Qiu, Xiangding Chen, Zheng Wang, Jianguo Cao
Pages: 2506-2515
Published online on: 01 July 2020

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Review

Therapeutic implications of fibroblast growth factor receptor inhibitors in a combination regimen for solid tumors (Review)

Hong Luo, Tao Zhang, Peng Cheng, Dong Li, Oleksandr Ogorodniitchouk, Chaimaa Lahmamssi, Ge Wang, Meiling Lan
Pages: 2525-2536
Published online on: 10 July 2020

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Review Open Access

Role of microRNA‑33a in malignant cells (Review)

Chang Gao, Jiaen Wei, Tingting Tang, Zunnan Huang
Pages: 2537-2556
Published online on: 09 July 2020

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Review Open Access

Targeting complexes of super‑enhancers is a promising strategy for cancer therapy (Review)

Chuqian Zheng, Min Liu, Hong Fan
Pages: 2557-2566
Published online on: 10 July 2020

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Review Open Access

Effects of aspirin on the gastrointestinal tract: Pros vs. cons (Review)

Zhuoya Li, Zheng Wang, Baile Shen, Chen Chen, Xiaoyun Ding, Haojun Song
Pages: 2567-2578
Published online on: 06 July 2020

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Review Open Access

Shank‑associated RH domain interactor signaling in tumorigenesis (Review)

Chong Zeng, Dan Xiong, Ketao Zhang, Jie Yao
Pages: 2579-2586
Published online on: 09 July 2020

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Review Open Access

Long non‑coding RNA GAS5 in human cancer (Review)

Xiaoyan Yang, Zhizhong Xie, Xiaoyong Lei, Runliang Gan
Pages: 2587-2594
Published online on: 03 July 2020

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Review Open Access

Atonal bHLH transcription factor 1 is an important factor for maintaining the balance of cell proliferation and differentiation in tumorigenesis (Review)

Ying Fu, Sha‑Sha Yuan, Li‑Jie Zhang, Zhi‑Li Ji, Xiao‑Jiang Quan
Pages: 2595-2605
Published online on: 08 July 2020

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Article Open Access

Research progress regarding the role of long non‑coding RNAs in osteosarcoma (Review)

Yanli Zhang, Yanchuan Pu, Jin Wang, Zicai Li, Hulin Wang
Pages: 2606-2612
Published online on: 03 July 2020

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Downregulation of the let‑7 family of microRNAs may promote insulin receptor/insulin‑like growth factor signalling pathways in pancreatic ductal adenocarcinoma

Ekene Emmanuel Nweke, Martin Brand
Pages: 2613-2620
Published online on: 10 July 2020

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Distinct prognostic values and antitumor effects of tumor growth factor β1 and its receptors in gastric cancer

Fengping Liu, Hongwei Wang, Mei Zhang
Pages: 2621-2632
Published online on: 09 July 2020

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SMAD‑6, ‑7 and ‑9 are potential molecular biomarkers for the prognosis in human lung cancer

Shuxian Pan, Guangming Zhou, Wentao Hu, Hailong Pei
Pages: 2633-2644
Published online on: 09 July 2020

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Identification of the association between HMMR expression and progression of hepatocellular carcinoma via construction of a co‑expression network

Donglan Lu, Xue Bai, Qiyuan Zou, Zuhuan Gan, Yufeng Lv
Pages: 2645-2654
Published online on: 09 July 2020

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CD8+ T cells located in tertiary lymphoid structures are associated with improved prognosis in patients with gastric cancer

Qing Li, Dachuan Zhang, Wenting He, Tongbing Chen, Zhantao Yan, Xie Gao, Lujun Chen, Xiao Zheng, Bin Xu, Binfeng Lu, Jingting Jiang
Pages: 2655-2664
Published online on: 08 July 2020

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Extranodal NK/T‑cell lymphoma, nasal type without evidence of EBV infection

Wei Wang, Lin Nong, Li Liang, Yalin Zheng, Dong Li, Xin Li, Ting Li
Pages: 2665-2676
Published online on: 09 July 2020

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Effect of CEACAM6 silencing on the biological behavior of human gallbladder cancer cells

Chengming Tian, Bingye Zhang, Chunlin Ge
Pages: 2677-2688
Published online on: 03 July 2020

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xCT inhibitor sulfasalazine depletes paclitaxel‑resistant tumor cells through ferroptosis in uterine serous carcinoma

Akiko Sugiyama, Tsuyoshi Ohta, Miyuki Obata, Kanako Takahashi, Manabu Seino, Satoru Nagase
Pages: 2689-2700
Published online on: 06 July 2020

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Tumor budding index and microvessel density assessment in patients with endometrial cancer: A pilot study

Tomasz Kluz, Tomasz Łoziński, Sylwia Czekierdowska, Norbert Stachowicz, Grzegorz Gurynowicz, Mieczysław Chróściel, Artur Czekierdowski
Pages: 2701-2710
Published online on: 03 July 2020

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Prognostic value of CXCL17 and CXCR8 expression in patients with colon cancer

Hongyan Yao, Yufeng Lv, Xuefeng Bai, Zhaojin Yu, Xiaojian Liu
Pages: 2711-2720
Published online on: 07 July 2020

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Exosomal miR‑34b inhibits proliferation and the epithelial‑mesenchymal transition by targeting Notch2 in ovarian cancer

Shenglian Lu, Wuxia Liu, Hong Shi, Han Zhou
Pages: 2721-2728
Published online on: 09 July 2020

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High expression of endothelial progenitor cell‑induced angiogenic markers is associated with bile acid levels in HCC

Jiang‑Long Chen, Long Wang, Rong Li, Ying‑Fu Jiao, Wei‑Feng Yu
Pages: 2729-2738
Published online on: 06 July 2020

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A meta‑analysis of the added value of diffusion weighted imaging in combination with contrast‑enhanced magnetic resonance imaging for the diagnosis of small hepatocellular carcinoma lesser or equal to 2 cm

Hailong Lan, Guisen Lin, Weizhi Zhong
Pages: 2739-2748
Published online on: 03 July 2020

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Expression and clinical significance of methyl‑CpG binding domain protein 2 in high‑grade serous ovarian cancer

Wangang Gong, Maowei Ni, Zhongbo Chen, Zhiguo Zheng
Pages: 2749-2756
Published online on: 09 July 2020

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miR‑502‑5p inhibits the proliferation, migration and invasion of gastric cancer cells by targeting SP1

Xiaobo Peng, Meihong Wu, Wuxia Liu, Chengtao Guo, Lixing Zhan, Xianbao Zhan
Pages: 2757-2762
Published online on: 03 July 2020

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Systemic inflammatory indices predict tumor response to neoadjuvant chemoradiotherapy for locally advanced rectal cancer

Sicong Lai, Liang Huang, Shuangling Luo, Zhanzhen Liu, Jianghui Dong, Liping Wang, Liang Kang
Pages: 2763-2770
Published online on: 03 July 2020

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Expression of miR-129-5p and miR-433 in the serum of breast cancer patients and their relationship with clinicopathological features

Jinhui Xue, Xiaohan Zhu, Pei Huang, Yingying He, Yanjing Xiao, Ruihan Liu, Min Zhao
Pages: 2771-2778
Published online on: 08 July 2020

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Long non‑coding RNA BCAR4 promotes liver cancer progression by regulating proliferation, migration and invasion

Aiyao Wang, Jun Meng, Hui Liu, Chen Li, Zhiyong Zhou
Pages: 2779-2787
Published online on: 08 July 2020

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High S phase kinase‑associated protein 2 expression is a potential prognostic biomarker for glioma

Zhi‑Jian Cheng, Hong‑Qing Cai, Min‑Jie Zhang, Yi Zhong, Jie He, Qing Yuan, Jia‑Jie Hao, Ming‑Rong Wang, Jing‑Hai Wan
Pages: 2788-2796
Published online on: 07 July 2020

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Diagnostic performance of a nomogram incorporating cribriform morphology for the prediction of adverse pathology in prostate cancer at radical prostatectomy

Baojun Wang, Jie Gao, Qing Zhang, Yao Fu, Guangxiang Liu, Chengwei Zhang, Wang Wei, Haifeng Huang, Jiong Shi, Danyan Li, Hongqian Guo
Pages: 2797-2805
Published online on: 10 July 2020

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MicroRNA‑125b reduces glucose uptake in papillary thyroid carcinoma cells

Guowu Zhang, Sihai Zhou, Quan Yang, Fang Liu
Pages: 2806-2810
Published online on: 08 July 2020

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MRI and the pathology of breast invasive micropapillary carcinoma

Chun‑Hong Han, Wei‑Gen Yao, Jie He, Zhi‑Bin Gao, Hong‑Jie Hu
Pages: 2811-2819
Published online on: 09 July 2020

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Next generation sequencing‑based analysis of mitochondrial DNA characteristics in plasma extracellular vesicles of patients with hepatocellular carcinoma

Yijie Li, Xu Guo, Shanshan Guo, Yang Wang, Lin Chen, Yang Liu, Min Jia, Jiaze An, Kaishan Tao, Jinliang Xing
Pages: 2820-2828
Published online on: 08 July 2020

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Genetic features and application value of next generation sequencing in the diagnosis of synchronous multifocal lung adenocarcinoma

Xiaoyan Chen, Jun Lu, Yingying Wu, Xingran Jiang, Yajuan  Gu, Yunlong Li, Hongying Zhao, Mulan Jin
Pages: 2829-2839
Published online on: 09 July 2020

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High expression of EMP1 predicts a poor prognosis and correlates with immune infiltrates in bladder urothelial carcinoma

Bo Lin, Tianwen Zhang, Xin Ye, Hongyu Yang
Pages: 2840-2854
Published online on: 09 July 2020

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SREBP1 silencing inhibits the proliferation and motility of human esophageal squamous carcinoma cells via the Wnt/β‑catenin signaling pathway

Jingzhi Wang, Rui Ling, Yuepeng Zhou, Xingyu Gao, Yun Yang, Chaoming Mao, Deyu Chen
Pages: 2855-2869
Published online on: 10 July 2020

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Telomerase inhibition decreases esophageal squamous carcinoma cell migration and invasion

Jiayan Li, Guogang Dong, Jinyun Song, Guolei Tan, Xuping Wu
Pages: 2870-2880
Published online on: 03 July 2020

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Correlation of APE1 with VEGFA and CD163+ macrophage infiltration in bladder cancer and their prognostic significance

Lin-Ang Wang, Bo Yang, Tang Tang, Yuxin Yang, Dianzheng Zhang, Hualiang Xiao, Jing Xu, Luofu Wang, Li Lin, Jun Jiang
Pages: 2881-2887
Published online on: 06 July 2020

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Establishment of highly invasive pancreatic cancer cell lines and the expression of IL‑32

Kohji Takagi, Johji Imura, Akiko Shimomura, Akira Noguchi, Takashi Minamisaka, Shinichi Tanaka, Takeshi Nishida, Hideki Hatta, Takahiko Nakajima
Pages: 2888-2896
Published online on: 08 July 2020

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USP9X promotes the proliferation, invasion and metastasis of liver cancer cells through regulating the JAK2/STAT3 signaling

Xingchao Song, Weibin Yang, Chao Wu, Yamin Han, Yaowu Lu
Pages: 2897-2905
Published online on: 08 July 2020

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A 10‑gene signature as a predictor of biochemical recurrence after radical prostatectomy in patients with prostate cancer and a Gleason score ≥7

Xiangkun Wu, Daojun Lv, Ming Lei, Chao Cai, Zhijian Zhao, Md Eftekhar, Di Gu, Yongda Liu
Pages: 2906-2918
Published online on: 08 July 2020

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Ring box protein-1 is associated with a poor prognosis and tumor progression in esophageal cancer

Tomohiro Kunishige, Kazuhiro Migita, Sohei Matsumoto, Kohei Wakatsuki, Hiroshi Nakade, Shintaro Miyao, Hiroki Kuniyasu, Masayuki Sho
Pages: 2919-2927
Published online on: 09 July 2020

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Polyphyllin II inhibits human bladder cancer migration and invasion by regulating EMT‑associated factors and MMPs

Weipin Niu, Li Xu, Jingwei Li, Yi Zhai, Zhonghua Sun, Wei Shi, Yuehua  Jiang, Chenchen Ma, Haiqing Lin, Yanxia Guo, Zhiyong Liu
Pages: 2928-2936
Published online on: 09 July 2020

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Selection of a malignant subpopulation from a colorectal cancer cell line

Pei‑Lun Lai, Ting‑Chun Chen, Chun‑Yen Feng, Hsuan Lin, Chi‑Hou Ng, Yun Chen, Michael Hsiao, Jean Lu, Hsiao‑Chun Huang
Pages: 2937-2945
Published online on: 08 July 2020

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Reduced expression of odd‑skipped related transcription factor 1 promotes proliferation and invasion of breast cancer cells and indicates poor patient prognosis

Yuan Wang, Lei Lei, Fang Xu, Hong‑Tao Xu
Pages: 2946-2954
Published online on: 07 July 2020

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miR‑452‑5p and miR‑215‑5p expression levels in colorectal cancer tissues and their relationship with clinicopathological features

Jingbo Yan, Ru Wei, Hui Li, Yan Dou, Junhui Wang
Pages: 2955-2961
Published online on: 09 July 2020

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Article

Long non‑coding RNA‑ZNF281 upregulates PTEN expression via downregulation of microRNA‑221 in non‑small cell lung cancer

Xin Lu, Bin Yin, Xuekun Wang, Fengchan Wang, Yue Li, Na Wang, Xinai Yang, Wenqing Jiang
Pages: 2962-2968
Published online on: 07 July 2020

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Characterization and imaging of surgical specimens of invasive breast cancer and normal breast tissues with the application of Raman spectral mapping: A feasibility study and comparison with randomized single‑point detection method

Haipeng Zhang, Xiaozhen Wang, Rongbo Ding, Lishengnan Shen, Pin Gao, Hui Xu, Caifeng Xiu, Huanxia Zhang, Dong Song, Bing Han
Pages: 2969-2976
Published online on: 03 July 2020

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Article

Early response of bone metastases can predict tumor response in patients with non‑small‑cell lung cancer with bone metastases in the treatment with nivolumab

Eiji Nakata, Shinsuke Sugihara, Yoshifumi Sugawara, Toshiyuki Kozuki, Daijiro Harada, Naoyuki Nogami, Ryuichi Nakahara, Takayuki Furumatsu, Tomonori Tetsunaga, Toshiyuki Kunisada, Toshifumi Ozaki
Pages: 2977-2986
Published online on: 10 July 2020

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Article

Quantitative volumetric assessment of the solid portion percentage on CT images to predict ROS1/ALK rearrangements in lung adenocarcinomas

Jing Zheng, Jianya Zhou, Jinpeng Liu, Jingfeng Xu, Ke  Sun, Bo  Wang, He Cao, Wei Ding, Jianying Zhou
Pages: 2987-2996
Published online on: 06 July 2020

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Inhibition of Rac1 reverses enzalutamide resistance in castration‑resistant prostate cancer

Xiaoliang Chen, Lili Yin, Gan Qiao, Yanhua Li, Baoyuan Li, Yunfeng Bai, Feng Feng
Pages: 2997-3005
Published online on: 08 July 2020

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Adenovirus‑mediated overexpression of interleukin‑21 regulates the development of oral squamous cell carcinoma in vitro

Hao Liu, Peng Liu, Di Sun, Dayuan Xing, Xiaoping Wang, Jinge Yang, Shengzhi Wang
Pages: 3006-3014
Published online on: 07 July 2020

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Article

MicroRNA‑574‑3p inhibits the malignant behavior of liver cancer cells by targeting ADAM28 Retraction in /10.3892/ol.2023.13973

Zhongming Zha, Fuxin Jia, Pingan Hu, Erhui Mai, Ting Lei
Pages: 3015-3023
Published online on: 10 July 2020

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Article

Long non‑coding RNA NBAT1 inhibits the progression of glioma through the miR‑21/SOX7 axis

Ning Guan, Rui Wang, Xu Feng, Chenguang Li, Wenshi Guo
Pages: 3024-3034
Published online on: 09 July 2020

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Article

Clinical outcomes and safety of apatinib monotherapy in the treatment of patients with advanced epithelial ovarian carcinoma who progressed after standard regimens and the analysis of the VEGFR2 polymorphism

Zhen Yan, Yuan‑Yuan Gu, Xiao‑Di Hu, Qun Zhao, Hai‑Li  Kang, Miao Wang, Wei Duan, Yin Guan
Pages: 3035-3045
Published online on: 10 July 2020

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Article

Comparison of the diagnostic value of CEA combined with OPN or DKK1 in non‑small cell lung cancer

Jinlin Sun, Xudong Chen, Yansen Wang
Pages: 3046-3052
Published online on: 09 July 2020

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Article

The combination of orlistat, lonidamine and 6‑diazo‑5‑oxo‑L‑norleucine induces a quiescent energetic phenotype and limits substrate flexibility in colon cancer cells

Alejandro Schcolnik‑Cabrera, Alma Chavez‑Blanco, Guadalupe Dominguez‑Gomez, Mandy Juarez, Donna Lai, Sheng Hua, Armando R. Tovar, Jose Diaz‑Chavez, Alfonso Duenas‑Gonzalez
Pages: 3053-3060
Published online on: 09 July 2020

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Correction Open Access

[Corrigendum] Characterization of an orthotopic gastric cancer mouse model with lymph node and organ metastases using bioluminescence imaging

Hai-Yi Feng, Yunpeng Zhang, Hai-Jun Liu, Xiao Dong, Si-Cong Yang, Qin Lu, Fanping Meng, Hong-Zhuan Chen, Peng Sun, Chao Fang
Pages: 3061-3061
Published online on: 10 July 2020

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[Corrigendum] Knockdown of pseudogene DUXAP8 expression in glioma suppresses tumor cell proliferation

Xu Zhao, Shuai Hao, Minqing Wang, Deguang Xing, Chengwei Wang
Pages: 3062-3062
Published online on: 10 July 2020

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Impact Factor: 2.2

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CiteScore Rank: Q2: #178/415 Oncology

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Article Open Access

Predictive analysis of BRAF V600E mutation and central lymph node metastasis in papillary thyroid carcinoma

Junhui Peng, Zhihui Wu, Yujun Huang, Runhua Pan, Zhongdai Fu, Jianzhang Wang
Article Number: 44
Published online on: 24 November 2025

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Case Report Open Access

Adverse events induced by the subcutaneous HER2-targeted antibody‑drug conjugate JSKN033 in a male patient with breast cancer: A case report

Rui Yang, Jian Zhang, Yang Wang
Article Number: 43
Published online on: 24 November 2025

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Prediction of solitary ≤3‑cm small adrenal metastasis based on 18F‑FDG PET/CT using a support vector machine model in lung cancer

Lin Zhao, Haifeng Cai, Jingwu Li, Wenzhe Zhao, Yongliang Liu, Lixiu Cao
Article Number: 42
Published online on: 24 November 2025

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Transferrin receptor serves a role in promoting PANoptosis in thyroid cancer

Shungao Ma, Zhiqiang Ma, Jingwei Shen, Hong Liu, Hua Yang, Yuqin Hu, Simeng Ying
Article Number: 41
Published online on: 24 November 2025

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Review Open Access

Oxidative stress as a nexus: Integrating mitophagy and ferroptosis in endometrial carcinogenesis (Review)

Qixia Yu, Liangxin Ren, Feng Ren, Fengling Li
Article Number: 40
Published online on: 20 November 2025

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Review Open Access

Astragalin: A promising herbal compound with broad anticancer potential (Review)

Yu-Qian Fu, Chan Li, Dan-Ni Ding, Fang-Yuan Liu, Yu-Fei Zhu, Feng-Juan Han
Article Number: 39
Published online on: 20 November 2025

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Analysis of prognostic factors influencing brain metastasis in EGFR‑mutant lung adenocarcinoma and comparison of prognostic assessment models

Junjun Miao, Jianwei Hu, Yongxia Zhang, Lei Gao, Xiangkun Yuan
Article Number: 38
Published online on: 18 November 2025

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Case Report

Fumarate hydratase-deficient renal cell carcinoma arising in acquired cystic kidney disease in a hemodialysis patient: Diagnostic clues from percutaneous renal mass core needle biopsy: A case report

Yuki Oba, Hisashi Kamido, Kei Kono, Katsuyuki Miki, Shinji Ito, Akinari Sekine, Shigekazu Kurihara, Masayuki Yamanouchi, Tatsuya Suwabe, Yutaka Takazawa, Kenichi Ohashi, Yoji Nagashima, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa
Article Number: 37
Published online on: 18 November 2025

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TIMP1 expression in colorectal cancer: Linking prognosis, tumor immunity and molecular pathways

Jiming Gu, Dongming Zhu, Fan Chen, Tongguo Shi, Suhua Xia
Article Number: 36
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer

Su-Liang Li, Na An, Bing Liu, Sheng-Yu Wang, Jian-Jun Wang, Yun Ye
Article Number: 35
Published online on: 17 November 2025

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Article

TAS‑102 plus bevacizumab as salvage treatment in colorectal cancer: A retrospective study

Keita Matsumoto, Ryoma Yokoi, Chika Mizutani, Ryuichi Asai, Jesse Yu Tajima, Masahide Endo, Yuji Hatanaka, Takeshi Horaguchi, Masahiro Fukada, Itaru Yasufuku, Yuta Sato, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi
Article Number: 34
Published online on: 14 November 2025

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Review Open Access

Research progress on neutrophil extracellular traps and hepatitis‑to‑hepatocellular carcinoma transformation (Review)

Yiwei Wang, Chengyan Zhang, Haonan Wang, Yali Zhou, Yuanbo Yu, Hui Liu, Chuansha Gu
Article Number: 33
Published online on: 14 November 2025

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Case Report Open Access

Remarkable response to Osimertinib plus Gumarontinib for EGFR mutation and concomitant MET exon 14 skipping in a patient with lung adenocarcinoma: A case report

Xuquan Jing, Li Li, Shuangqing Lu, Xiaoyang Zhai, Hui Zhu
Article Number: 32
Published online on: 12 November 2025

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Article Open Access

Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene

Yufan Zhou, Wei Liu, Zhixue Fang, Ke Zhou, Xing Huang, Shanzheng Lu, Weilin Zhang, Qiaocheng Wen, Xu Chen, Zhigang Xiao
Article Number: 31
Published online on: 12 November 2025

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Case Report Open Access

Dual immune checkpoint inhibitor cardonilumab induces immune myocarditis in a patient with cancer‑related myocardial metastasis: A case report

Tianxing Liu, Qiang Li, Renya Zeng, Baidong Zhang, Zhichao Kang, Pengfei Zhang, Zhe Yang
Article Number: 30
Published online on: 12 November 2025

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Article Open Access

Retrospective analysis of clinical characteristics, treatment outcomes and prognosis of patients with natural killer/T‑cell lymphoma

Pengye Li, Geraldine Esther Awakossa, Lu Zhou, Qiuhui Li, Xinxiu Liu, Fang Zhu, Tao Liu, Liling Zhang
Article Number: 29
Published online on: 11 November 2025

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Review Open Access

From mechanism to targeted therapy: Advances in histone lactylation‑driven cancer progression (Review)

Zhe Jia, Shan Lu, Zhenchuan Wang, Pengfei Ge
Article Number: 28
Published online on: 11 November 2025

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Retraction Open Access

[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
Published online on: 10 November 2025

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Review Open Access

Biology of PEST‑containing nuclear proteins as potential targets in ovarian cancer (Review)

Hao Liu, Zhi-Liang Jiang, Yi Liu, Yong-Hao Zhu, Muhammad Usman Akbar, Saadullah Khattak, Zhendong Lu, Muhammad Babar Khawar, Yue Zhang, Umair Ali Khan Saddozai, Xin-Ying Ji
Article Number: 26
Published online on: 07 November 2025

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Article

Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Article Open Access

Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

Sha Huang, Zhengwei Huang, Zhoujian Sun, Tianao Xie, Xingyu Zhu, Sheng Lu, Zhengxing Huang, Jian Hu, Zhengfu He
Article Number: 24
Published online on: 06 November 2025

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Article Open Access

Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
Article Number: 23
Published online on: 06 November 2025

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Review

Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Review Open Access

Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

Haoyan Zhuang, Xuewen Shi
Article Number: 21
Published online on: 04 November 2025

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Review Open Access

Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

Tao Shi, Jianping Kang, Qiyang Wang, Jiamei Song, Xiaofeng He
Article Number: 20
Published online on: 04 November 2025

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Article Open Access

Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Case Report Open Access

Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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Retraction Open Access

[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Article Open Access

Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Article Open Access

Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Review Open Access

Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Article Open Access

Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Review Open Access

Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Article Open Access

Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Case Report Open Access

Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Review Open Access

Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Case Report Open Access

Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Case Report Open Access

Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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February-2026 Volume 31 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Primary bone marrow diffuse large B‑cell lymphoma with secondary myelofibrosis: A case report

Jing Yang, Sheng-Ke Tu, Hui Peng, Yuan-Yuan Peng, Min Li, Kui Song
Article Number: 70
Published online on: 05 December 2025

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Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Review Open Access

Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Case Report Open Access

Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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Retraction Open Access

[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Case Report Open Access

Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Article

Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Review Open Access

Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Article Open Access

Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Case Report Open Access

Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Case Report Open Access

Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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Article Open Access

SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Article Open Access

Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Case Report Open Access

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Review Open Access

Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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