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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2020 Volume 20 Issue 3

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Timing of breast cancer surgery during the menstrual cycle‑is there an optimal time of the month? (Review)

Sarah M. Bernhardt, Pallave Dasari, David Walsh, Amanda R. Townsend, Timothy J. Price, Wendy V. Ingman
Pages: 2045-2057
Published online on: 24 June 2020

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Review Open Access

Cervical cancer in low and middle‑income countries (Review)

Rodney Hull, Mzwandile Mbele, Tshepiso Makhafola, Chindo Hicks, Shao‑Ming Wang, Rui Manuel Reis, Ravi Mehrotra, Zilungile Mkhize‑Kwitshana, Gibson Kibiki, David O. Bates, Zodwa Dlamini
Pages: 2058-2074
Published online on: 19 June 2020

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Review Open Access

Immune disorder in endometrial cancer: Immunosuppressive microenvironment, mechanisms of immune evasion and immunotherapy (Review)

Lei Zhan, Xiaojing Liu, Jing Zhang, Yunxia Cao, Bing Wei
Pages: 2075-2090
Published online on: 25 June 2020

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Review Open Access

Implications of lipid droplets in lung cancer: Associations with drug resistance (Review)

Chunlai Jin, Peng Yuan
Pages: 2091-2104
Published online on: 24 June 2020

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Article Open Access

Konjac glucomannan reverses multi‑drug resistance of HepG2/5‑FU cells by suppressing AKT signaling and increasing p53 expression

Bin Chen, Xin Xu, Ke Zheng, Ling Liu, Yijun Yu, Ying Xin
Pages: 2105-2112
Published online on: 01 July 2020

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Article Open Access

Increase in CD4+FOXP3+ regulatory T cell number and upregulation of the HGF/c‑Met signaling pathway during the liver metastasis of colorectal cancer

Xiaoming Huang, Zexian Chen, Nanrong Zhang, Caiyan Zhu, Xutao Lin, Jiandong Yu, Zhiping Chen, Ping Lan, Yunle Wan
Pages: 2113-2118
Published online on: 26 June 2020

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Article Open Access

Effect of KRAS and NRAS mutations on the prognosis of patients with synchronous metastatic colorectal cancer presenting with liver‑only and lung‑only metastases

Shih‑Chang Chuang, Ching‑Wen Huang, Yi‑Ting Chen, Cheng‑Jen Ma, Hsiang‑Lin Tsai, Tsung‑Kun Chang, Wei‑Chih Su, Wen‑Hung Hsu, Chao‑Hung Kuo, Jaw‑Yuan Wang
Pages: 2119-2130
Published online on: 01 July 2020

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Article Open Access

Regorafenib treatment outcome for Taiwanese patients with metastatic gastrointestinal stromal tumors after failure of imatinib and sunitinib: A prospective, non‑randomized, single‑center study

Chia‑Hsiang Hu, Chun‑Nan Yeh, Jen‑Shi Chen, Chun‑Yi Tsai, Shang‑Yu Wang, Chi‑Tung Cheng, Ta‑Sen Yeh
Pages: 2131-2142
Published online on: 19 June 2020

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Article Open Access

Prognostic and predictive value of monocarboxylate transporter 4 in patients with breast cancer

Sheng Xiao, Hongjia Zhu, Yujun Shi, Zhenru Wu, Hegang Wu, Mingjun Xie
Pages: 2143-2152
Published online on: 25 June 2020

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Article Open Access

Relationship between the immunohistological examination and fluorescence visualization of oral squamous cell carcinoma

Keisuke Sugahara, Yu Koyama, Masahide Koyachi, Satoru Matsunaga, Kento Odaka, Kei Kitamura, Kei Nakajima, Kenichi Matsuzaka, Shinichi Abe, Akira Katakura
Pages: 2153-2160
Published online on: 24 June 2020

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Article Open Access

Interferon‑γ induced PD‑L1 expression and soluble PD‑L1 production in gastric cancer

Yushi Imai, Tetsuhiro Chiba, Takayuki Kondo, Hiroaki Kanzaki, Kengo  Kanayama, Junjie  Ao, Ryuta Kojima, Yuko Kusakabe, Masato  Nakamura, Tomoko  Saito, Ryo Nakagawa, Eiichiro Suzuki, Shingo Nakamoto, Ryosuke  Muroyama, Akinobu Tawada, Tomoaki Matsumura, Tomoo  Nakagawa, Jun Kato, Ai Kotani, Hisahiro Matsubara, Naoya Kato
Pages: 2161-2168
Published online on: 19 June 2020

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Article Open Access

Structure identification, antitumor activity and mechanisms of a novel polysaccharide from Ramaria flaccida (Fr.) Quél

Mingming Dong, Yiling Hou, Xiang Ding
Pages: 2169-2182
Published online on: 19 June 2020

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Article Open Access

LncRNA MEG3 inhibits non‑small cell lung cancer via interaction with DKC1 protein

Zhi Yang, Zitong Wang, Yong Duan
Pages: 2183-2190
Published online on: 24 June 2020

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Article Open Access

Knockdown of m6A methyltransferase METTL3 in gastric cancer cells results in suppression of cell proliferation

Li Jiang, Ting Chen, Li Xiong, Ji‑Hao Xu, Ai‑Yu Gong, Bin Dai, Ganlin Wu, Kenny Zhu, Eugene Lu, Nicholas William Mathy, Xian‑Ming Chen
Pages: 2191-2198
Published online on: 01 July 2020

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Article Open Access

Circular RNA profiling in plasma exosomes from patients with gastric cancer

Min Rao, Yonggang Zhu, Lingzhi Qi, Feng Hu, Pujun Gao
Pages: 2199-2208
Published online on: 01 July 2020

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Article Open Access

Limb‑bud and heart as a novel biomarker for gastric intestinal type adenocarcinoma

Shu‑Sheng Wu, Jian Chen, Ying Yan, Hui‑Qin Luo, Wen‑Ju Chen, Yi‑Fu He
Pages: 2209-2216
Published online on: 25 June 2020

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Article Open Access

Effects of different preoperative biliary drainage methods for resected malignant obstruction jaundice on the incidence rate of implantation metastasis: A meta‑analysis

Gang Yang, Yongfu Xiong, Ji Sun, Tao Tang, Weinan Li, Guan Wang, Jingdong Li
Pages: 2217-2224
Published online on: 24 June 2020

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Article Open Access

MicroRNA‑101 suppresses colorectal cancer progression by negative regulation of Rap1b

Zhiyuan Zhou, Hang Xu, Yantao Duan, Bin Liu
Pages: 2225-2231
Published online on: 01 July 2020

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Article Open Access

Value of shear wave elastography in the diagnosis and evaluation of cervical cancer

Bing Fu, Hong Zhang, Zhen‑Wei Song, Ji‑Xiang Lu, Shi‑Hui Wu, Jie Li
Pages: 2232-2238
Published online on: 19 June 2020

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Article Open Access

miR129‑1 regulates protein phosphatase 1D protein expression under hypoxic conditions in non‑small cell lung cancer cells harboring a TP53 mutation

Hong‑Lei Yin, Hong‑Wei Xu, Qing‑Yan Lin
Pages: 2239-2247
Published online on: 26 June 2020

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Article Open Access

Stanniocalcin 1 is a prognostic biomarker in glioma

Weijian Luo, Dong Chen, Hao Wang, Jiliang Hu
Pages: 2248-2256
Published online on: 01 July 2020

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Article Open Access

Lenvatinib prolongs the progression‑free survival time of patients with intermediate‑stage hepatocellular carcinoma refractory to transarterial chemoembolization: A multicenter cohort study using data mining analysis

Shigeo Shimose, Takumi Kawaguchi, Masatoshi Tanaka, Hideki Iwamoto, Ken Miyazaki, Etsuko Moriyama, Hiroyuki Suzuki, Takashi Niizeki, Tomotake Shirono, Masahito Nakano, Hideya Suga, Taizo Yamaguchi, Yoshinori Yokokura, Kazunori Noguchi, Hironori Koga, Takuji Torimura
Pages: 2257-2265
Published online on: 19 June 2020

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Article Open Access

Patients with advanced non‑small cell lung cancer with EGFR mutations in addition to complex mutations treated with osimertinib have a poor clinical outcome: A real‑world data analysis

Nijia Chang, Jingjing Duan, Lingxiong Wang, Zhouhuan Dong, Zhefeng Liu
Pages: 2266-2272
Published online on: 01 July 2020

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Article Open Access

Mutation analysis and genomic imbalances of cells found in effusion fluids from patients with ovarian cancer

Marta Brunetti, Ioannis Panagopoulos, Ilyá Kostolomov, Ben Davidson, Sverre Heim, Francesca Micci
Pages: 2273-2279
Published online on: 26 June 2020

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Article Open Access

Use of peripheral blood transcriptomic biomarkers to distinguish high‑grade cervical squamous intraepithelial lesions from low‑grade lesions

Cunhua Zou, Yali Lyu, Jing Jiang, Yuan Cao, Min Wang, Changmei Sang, Ruirui  Zhang, Haifeng Li, Choong‑Chin Liew, Changming Cheng, Shuping Zhao
Pages: 2280-2290
Published online on: 26 June 2020

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Article Open Access

Mechanistic studies of cytotoxic activity of the mesoionic compound MIH 2.4Bl in MCF‑7 breast cancer cells

Luciana Amaral de Mascena Costa, Dipti Debnath, Ashlyn C. Harmon, Silvany de Sousa Araújo, Helivaldo Diógenes da Silva Souza, Petrônio Filgueiras de Athayde Filho, Aurea Wischral, Manoel Adrião Gomes Filho, J. Michael Mathis
Pages: 2291-2301
Published online on: 19 June 2020

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Article Open Access

Potential five‑mRNA signature model for the prediction of prognosis in patients with papillary thyroid carcinoma

Lin‑Kun Zhong, Xiao‑Xiong Gan, Xing‑Yan Deng, Fei Shen, Jian‑Hua Feng, Wen‑Song Cai, Qiong‑Yao Liu, Jian‑Hang Miao, Bing‑Xing Zheng, Bo Xu
Pages: 2302-2310
Published online on: 26 June 2020

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Article Open Access

Small RNA profiles of HTLV‑1 asymptomatic carriers with monoclonal and polyclonal rearrangement of the T‑cell antigen receptor γ‑chain using massively parallel sequencing: A pilot study

Daniela Raguer Valadão de Souza, Rodrigo Pessôa, Andrezza Nascimento, Youko Nukui, Juliana Pereira, Jorge Casseb, Augusto César Penalva de Oliveira, Alberto José da Silva Duarte, Patricia Bianca Clissa, Sabri Saeed Sanabani
Pages: 2311-2321
Published online on: 01 July 2020

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Article Open Access

Effectiveness of fibrin sealant as a hemostatic technique in accelerating endoscopic submucosal dissection-induced ulcer healing and preventing stricture in the esophagus: A retrospective study

Jing Wang, Shao-Lei Li, Nan Wu, Qi Wu
Pages: 2322-2330
Published online on: 25 June 2020

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Article Open Access

γ‑H2AX as a potential indicator of radiosensitivity in colorectal cancer cells

Satoshi Kawashima, Nao Kawaguchi, Kohei Taniguchi, Keitaro Tashiro, Kazumasa Komura, Tomohito Tanaka, Yosuke Inomata, Yoshiro Imai, Ryo Tanaka, Masashi Yamamoto, Yoshihiro Inoue, Sang‑Woong Lee, Masaru Kawai, Keitaro Tanaka, Junji Okuda, Kazuhisa Uchiyama
Pages: 2331-2337
Published online on: 26 June 2020

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Article Open Access

CAF‑1/p150 promotes cell proliferation, migration, invasion and predicts a poor prognosis in patients with cervical cancer

Shu Yang, Qian Long, Min Chen, Xiao Liu , Hang Zhou
Pages: 2338-2346
Published online on: 25 June 2020

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Case Report Open Access

Primary intradural extramedullary Ewing sarcoma: A case report and literature review

Yuya Izubuchi, Hideaki Nakajima, Kazuya Honjoh, Yoshiaki Imamura, Takayuki Nojima, Akihiko Matsumine
Pages: 2347-2355
Published online on: 26 June 2020

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Article Open Access

High expression of GPNMB indicates an unfavorable prognosis in glioma: Combination of data from the GEO and CGGA databases and validation in tissue microarray

Xiao Feng, Lina Zhang, Shanbao Ke, Tao Liu, Liuwei  Hao, Pan Zhao, Wenzhi Tu, Shundong Cang
Pages: 2356-2368
Published online on: 26 June 2020

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Article Open Access

Synthetic MUC1 breast cancer vaccine containing a Toll‑like receptor 7 agonist exerts antitumor effects

Yu Liu, Li Tang, Ningning Gao, Yuwen Diao, Jingjing Zhong, Yongqiang Deng, Zhulin Wang, Guangyi Jin, Xiaodong Wang
Pages: 2369-2377
Published online on: 19 June 2020

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Article Open Access

Bioinformatics analysis of aberrantly expressed exosomal lncRNAs in oral squamous cell carcinoma (CAL‑27 vs. oral epithelial) cells

Jiajia Jin, Zixiao Huang, Xiaoyan Lu, Shengrong Wu, Mei'e Jia, Xin Li, Zhiyong Li, Xiangyi He
Pages: 2378-2386
Published online on: 24 June 2020

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Article Open Access

PAK6 promotes cervical cancer progression through activation of the Wnt/β‑catenin signaling pathway

Qin Yang, Yingchao Zhao, Yeshan Chen, Yu Chang, Ai Huang, Tie Xu, Guiling Li, Gang Wu
Pages: 2387-2395
Published online on: 01 July 2020

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Article Open Access

Identification of a five‑gene signature for predicting the progression and prognosis of stage I endometrial carcinoma

Jia Bian, Yuzi Xu, Fei Wu, Qiangwei Pan, Yunlong Liu
Pages: 2396-2410
Published online on: 01 July 2020

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Article Open Access

Downregulation of microRNA‑126 is inversely correlated with insulin receptor substrate‑1 protein expression in colorectal cancer and is associated with advanced stages of disease

Shicai Ye, Caiyuan Yu, Guixia Zhang, Feixiong Shi, Yongze  Chen, Jianyun Yang, Weiyun Wu, Yu Zhou
Pages: 2411-2419
Published online on: 01 July 2020

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Article Open Access

An optimal prognostic model based on gene expression for clear cell renal cell carcinoma

Dan Xu, Wantai Dang, Shaoqing Wang, Bo Hu, Lianghong Yin, Baozhang Guan
Pages: 2420-2434
Published online on: 26 June 2020

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Article Open Access

DNA mismatch repair is not disrupted in stage 0 colorectal cancer resected using endoscopic submucosal dissection

Tomohiro Sugiyama, Moriya Iwaizumi, Masanao Kaneko, Shinya Tani, Mihoko Yamade, Yasushi Hamaya, Takahisa Furuta, Hiroaki Miyajima, Satoshi Osawa, Satoshi Baba, Masato Maekawa, Ken Sugimoto
Pages: 2435-2441
Published online on: 01 July 2020

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Article Open Access

Prognostic potential of lncRNA RHPN1-AS1 in glioma

Yong Wu, Wuting Wei, Linjun Tang, Liangwei Wang
Pages: 2442-2446
Published online on: 25 June 2020

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Article Open Access

miR‑429 inhibits osteosarcoma progression by targeting HOXA9 through suppressing Wnt/β‑catenin signaling pathway

Liangzhi Sun, Libo Wang, Suxian Luan, Yanzhou Jiang, Qiang Wang
Pages: 2447-2455
Published online on: 24 June 2020

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Article Open Access

Diagnostic value and prognostic significance of LI‑cadherin and miR‑378e in colorectal cancer

Xujie Wang, Zhihua Li, Jixin Fu, Weiwei Xu, Zongxian Li
Pages: 2456-2464
Published online on: 19 June 2020

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Case Report

Clinical management of extrapleural septal solitary fibrous tumor: A case report

Michele Cavaliere, Eva Piro, Massimo Mascolo, Claudio Di Nola, Salvatore Allosso, Antonella M. Di Lullo, Gaetano Motta, Maurizio Iengo, Elena Cantone
Pages: 2465-2468
Published online on: 30 June 2020

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Article

Biomarker phenotyping drives clinical management in axillary sentinel node: A retrospective study on women with primary breast cancer in 2002

Sergio Diotaiuti, Simona De Summa, Rosanna  Altieri, Caterina  Dantona, Stefania  Tommasi, Maria  Di Gennaro, Giuseppe  Rubini, Maria   Irene Pastena, Antonella  Argentiero, Francesco   Alfredo Zito, Nicola  Silvestris, Angelo   Virgilio Paradiso
Pages: 2469-2476
Published online on: 01 July 2020

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Article

ERK‑mediated negative feedback regulation of oncogenic EGFRvIII in glioblastoma cells

Ratna Dini Haryuni, Tomohiro Tanaka, Yue Zhou, Satoru Yokoyama, Hiroaki Sakurai
Pages: 2477-2482
Published online on: 19 June 2020

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Article

Enhancement of piperlongumine chemosensitivity by silencing heme oxygenase‑1 expression in cholangiocarcinoma cell lines

Chutima Talabnin, Krajang Talabnin, Sopit Wongkham
Pages: 2483-2492
Published online on: 26 June 2020

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Article

Enhanced therapeutic effect of transcatheter arterial chemoembolization combined with radioactive I‑125 seed implantation on liver cancer

Wenbao Liu, Nanguang Xiu, Jinwei Zhao, Lianhao Zhao
Pages: 2493-2498
Published online on: 24 June 2020

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Article

ANGPTL4 overexpression is associated with progression and poor prognosis in breast cancer

Jing Zhao, Juntian Liu, Nan Wu, Hailian Zhang, Shichao Zhang, Lijuan Li, Meng Wang
Pages: 2499-2505
Published online on: 24 June 2020

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Article Open Access

Genistein inhibits lung cancer cell stem‑like characteristics by modulating MnSOD and FoxM1 expression Retraction in /10.3892/ol.2025.15097

Zhimin Fu, Xiaocheng Cao, Lihua Liu, Xiaozheng Cao, Yinghong Cui, Xiang Li, Meifang Quan, Kaiqun Ren, A Chen, Chang Xu, Yebei Qiu, Xiangding Chen, Zheng Wang, Jianguo Cao
Pages: 2506-2515
Published online on: 01 July 2020

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Review

Therapeutic implications of fibroblast growth factor receptor inhibitors in a combination regimen for solid tumors (Review)

Hong Luo, Tao Zhang, Peng Cheng, Dong Li, Oleksandr Ogorodniitchouk, Chaimaa Lahmamssi, Ge Wang, Meiling Lan
Pages: 2525-2536
Published online on: 10 July 2020

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Review Open Access

Role of microRNA‑33a in malignant cells (Review)

Chang Gao, Jiaen Wei, Tingting Tang, Zunnan Huang
Pages: 2537-2556
Published online on: 09 July 2020

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Review Open Access

Targeting complexes of super‑enhancers is a promising strategy for cancer therapy (Review)

Chuqian Zheng, Min Liu, Hong Fan
Pages: 2557-2566
Published online on: 10 July 2020

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Review Open Access

Effects of aspirin on the gastrointestinal tract: Pros vs. cons (Review)

Zhuoya Li, Zheng Wang, Baile Shen, Chen Chen, Xiaoyun Ding, Haojun Song
Pages: 2567-2578
Published online on: 06 July 2020

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Review Open Access

Shank‑associated RH domain interactor signaling in tumorigenesis (Review)

Chong Zeng, Dan Xiong, Ketao Zhang, Jie Yao
Pages: 2579-2586
Published online on: 09 July 2020

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Review Open Access

Long non‑coding RNA GAS5 in human cancer (Review)

Xiaoyan Yang, Zhizhong Xie, Xiaoyong Lei, Runliang Gan
Pages: 2587-2594
Published online on: 03 July 2020

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Review Open Access

Atonal bHLH transcription factor 1 is an important factor for maintaining the balance of cell proliferation and differentiation in tumorigenesis (Review)

Ying Fu, Sha‑Sha Yuan, Li‑Jie Zhang, Zhi‑Li Ji, Xiao‑Jiang Quan
Pages: 2595-2605
Published online on: 08 July 2020

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Article Open Access

Research progress regarding the role of long non‑coding RNAs in osteosarcoma (Review)

Yanli Zhang, Yanchuan Pu, Jin Wang, Zicai Li, Hulin Wang
Pages: 2606-2612
Published online on: 03 July 2020

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Downregulation of the let‑7 family of microRNAs may promote insulin receptor/insulin‑like growth factor signalling pathways in pancreatic ductal adenocarcinoma

Ekene Emmanuel Nweke, Martin Brand
Pages: 2613-2620
Published online on: 10 July 2020

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Distinct prognostic values and antitumor effects of tumor growth factor β1 and its receptors in gastric cancer

Fengping Liu, Hongwei Wang, Mei Zhang
Pages: 2621-2632
Published online on: 09 July 2020

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SMAD‑6, ‑7 and ‑9 are potential molecular biomarkers for the prognosis in human lung cancer

Shuxian Pan, Guangming Zhou, Wentao Hu, Hailong Pei
Pages: 2633-2644
Published online on: 09 July 2020

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Identification of the association between HMMR expression and progression of hepatocellular carcinoma via construction of a co‑expression network

Donglan Lu, Xue Bai, Qiyuan Zou, Zuhuan Gan, Yufeng Lv
Pages: 2645-2654
Published online on: 09 July 2020

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Article Open Access

CD8+ T cells located in tertiary lymphoid structures are associated with improved prognosis in patients with gastric cancer

Qing Li, Dachuan Zhang, Wenting He, Tongbing Chen, Zhantao Yan, Xie Gao, Lujun Chen, Xiao Zheng, Bin Xu, Binfeng Lu, Jingting Jiang
Pages: 2655-2664
Published online on: 08 July 2020

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Extranodal NK/T‑cell lymphoma, nasal type without evidence of EBV infection

Wei Wang, Lin Nong, Li Liang, Yalin Zheng, Dong Li, Xin Li, Ting Li
Pages: 2665-2676
Published online on: 09 July 2020

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Effect of CEACAM6 silencing on the biological behavior of human gallbladder cancer cells

Chengming Tian, Bingye Zhang, Chunlin Ge
Pages: 2677-2688
Published online on: 03 July 2020

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xCT inhibitor sulfasalazine depletes paclitaxel‑resistant tumor cells through ferroptosis in uterine serous carcinoma

Akiko Sugiyama, Tsuyoshi Ohta, Miyuki Obata, Kanako Takahashi, Manabu Seino, Satoru Nagase
Pages: 2689-2700
Published online on: 06 July 2020

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Tumor budding index and microvessel density assessment in patients with endometrial cancer: A pilot study

Tomasz Kluz, Tomasz Łoziński, Sylwia Czekierdowska, Norbert Stachowicz, Grzegorz Gurynowicz, Mieczysław Chróściel, Artur Czekierdowski
Pages: 2701-2710
Published online on: 03 July 2020

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Prognostic value of CXCL17 and CXCR8 expression in patients with colon cancer

Hongyan Yao, Yufeng Lv, Xuefeng Bai, Zhaojin Yu, Xiaojian Liu
Pages: 2711-2720
Published online on: 07 July 2020

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Exosomal miR‑34b inhibits proliferation and the epithelial‑mesenchymal transition by targeting Notch2 in ovarian cancer

Shenglian Lu, Wuxia Liu, Hong Shi, Han Zhou
Pages: 2721-2728
Published online on: 09 July 2020

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High expression of endothelial progenitor cell‑induced angiogenic markers is associated with bile acid levels in HCC

Jiang‑Long Chen, Long Wang, Rong Li, Ying‑Fu Jiao, Wei‑Feng Yu
Pages: 2729-2738
Published online on: 06 July 2020

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A meta‑analysis of the added value of diffusion weighted imaging in combination with contrast‑enhanced magnetic resonance imaging for the diagnosis of small hepatocellular carcinoma lesser or equal to 2 cm

Hailong Lan, Guisen Lin, Weizhi Zhong
Pages: 2739-2748
Published online on: 03 July 2020

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Expression and clinical significance of methyl‑CpG binding domain protein 2 in high‑grade serous ovarian cancer

Wangang Gong, Maowei Ni, Zhongbo Chen, Zhiguo Zheng
Pages: 2749-2756
Published online on: 09 July 2020

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miR‑502‑5p inhibits the proliferation, migration and invasion of gastric cancer cells by targeting SP1

Xiaobo Peng, Meihong Wu, Wuxia Liu, Chengtao Guo, Lixing Zhan, Xianbao Zhan
Pages: 2757-2762
Published online on: 03 July 2020

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Systemic inflammatory indices predict tumor response to neoadjuvant chemoradiotherapy for locally advanced rectal cancer

Sicong Lai, Liang Huang, Shuangling Luo, Zhanzhen Liu, Jianghui Dong, Liping Wang, Liang Kang
Pages: 2763-2770
Published online on: 03 July 2020

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Expression of miR-129-5p and miR-433 in the serum of breast cancer patients and their relationship with clinicopathological features

Jinhui Xue, Xiaohan Zhu, Pei Huang, Yingying He, Yanjing Xiao, Ruihan Liu, Min Zhao
Pages: 2771-2778
Published online on: 08 July 2020

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Long non‑coding RNA BCAR4 promotes liver cancer progression by regulating proliferation, migration and invasion

Aiyao Wang, Jun Meng, Hui Liu, Chen Li, Zhiyong Zhou
Pages: 2779-2787
Published online on: 08 July 2020

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High S phase kinase‑associated protein 2 expression is a potential prognostic biomarker for glioma

Zhi‑Jian Cheng, Hong‑Qing Cai, Min‑Jie Zhang, Yi Zhong, Jie He, Qing Yuan, Jia‑Jie Hao, Ming‑Rong Wang, Jing‑Hai Wan
Pages: 2788-2796
Published online on: 07 July 2020

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Diagnostic performance of a nomogram incorporating cribriform morphology for the prediction of adverse pathology in prostate cancer at radical prostatectomy

Baojun Wang, Jie Gao, Qing Zhang, Yao Fu, Guangxiang Liu, Chengwei Zhang, Wang Wei, Haifeng Huang, Jiong Shi, Danyan Li, Hongqian Guo
Pages: 2797-2805
Published online on: 10 July 2020

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MicroRNA‑125b reduces glucose uptake in papillary thyroid carcinoma cells

Guowu Zhang, Sihai Zhou, Quan Yang, Fang Liu
Pages: 2806-2810
Published online on: 08 July 2020

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MRI and the pathology of breast invasive micropapillary carcinoma

Chun‑Hong Han, Wei‑Gen Yao, Jie He, Zhi‑Bin Gao, Hong‑Jie Hu
Pages: 2811-2819
Published online on: 09 July 2020

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Next generation sequencing‑based analysis of mitochondrial DNA characteristics in plasma extracellular vesicles of patients with hepatocellular carcinoma

Yijie Li, Xu Guo, Shanshan Guo, Yang Wang, Lin Chen, Yang Liu, Min Jia, Jiaze An, Kaishan Tao, Jinliang Xing
Pages: 2820-2828
Published online on: 08 July 2020

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Genetic features and application value of next generation sequencing in the diagnosis of synchronous multifocal lung adenocarcinoma

Xiaoyan Chen, Jun Lu, Yingying Wu, Xingran Jiang, Yajuan  Gu, Yunlong Li, Hongying Zhao, Mulan Jin
Pages: 2829-2839
Published online on: 09 July 2020

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High expression of EMP1 predicts a poor prognosis and correlates with immune infiltrates in bladder urothelial carcinoma

Bo Lin, Tianwen Zhang, Xin Ye, Hongyu Yang
Pages: 2840-2854
Published online on: 09 July 2020

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SREBP1 silencing inhibits the proliferation and motility of human esophageal squamous carcinoma cells via the Wnt/β‑catenin signaling pathway

Jingzhi Wang, Rui Ling, Yuepeng Zhou, Xingyu Gao, Yun Yang, Chaoming Mao, Deyu Chen
Pages: 2855-2869
Published online on: 10 July 2020

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Telomerase inhibition decreases esophageal squamous carcinoma cell migration and invasion

Jiayan Li, Guogang Dong, Jinyun Song, Guolei Tan, Xuping Wu
Pages: 2870-2880
Published online on: 03 July 2020

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Correlation of APE1 with VEGFA and CD163+ macrophage infiltration in bladder cancer and their prognostic significance

Lin-Ang Wang, Bo Yang, Tang Tang, Yuxin Yang, Dianzheng Zhang, Hualiang Xiao, Jing Xu, Luofu Wang, Li Lin, Jun Jiang
Pages: 2881-2887
Published online on: 06 July 2020

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Establishment of highly invasive pancreatic cancer cell lines and the expression of IL‑32

Kohji Takagi, Johji Imura, Akiko Shimomura, Akira Noguchi, Takashi Minamisaka, Shinichi Tanaka, Takeshi Nishida, Hideki Hatta, Takahiko Nakajima
Pages: 2888-2896
Published online on: 08 July 2020

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Article Open Access

USP9X promotes the proliferation, invasion and metastasis of liver cancer cells through regulating the JAK2/STAT3 signaling

Xingchao Song, Weibin Yang, Chao Wu, Yamin Han, Yaowu Lu
Pages: 2897-2905
Published online on: 08 July 2020

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A 10‑gene signature as a predictor of biochemical recurrence after radical prostatectomy in patients with prostate cancer and a Gleason score ≥7

Xiangkun Wu, Daojun Lv, Ming Lei, Chao Cai, Zhijian Zhao, Md Eftekhar, Di Gu, Yongda Liu
Pages: 2906-2918
Published online on: 08 July 2020

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Article Open Access

Ring box protein-1 is associated with a poor prognosis and tumor progression in esophageal cancer

Tomohiro Kunishige, Kazuhiro Migita, Sohei Matsumoto, Kohei Wakatsuki, Hiroshi Nakade, Shintaro Miyao, Hiroki Kuniyasu, Masayuki Sho
Pages: 2919-2927
Published online on: 09 July 2020

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Polyphyllin II inhibits human bladder cancer migration and invasion by regulating EMT‑associated factors and MMPs

Weipin Niu, Li Xu, Jingwei Li, Yi Zhai, Zhonghua Sun, Wei Shi, Yuehua  Jiang, Chenchen Ma, Haiqing Lin, Yanxia Guo, Zhiyong Liu
Pages: 2928-2936
Published online on: 09 July 2020

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Selection of a malignant subpopulation from a colorectal cancer cell line

Pei‑Lun Lai, Ting‑Chun Chen, Chun‑Yen Feng, Hsuan Lin, Chi‑Hou Ng, Yun Chen, Michael Hsiao, Jean Lu, Hsiao‑Chun Huang
Pages: 2937-2945
Published online on: 08 July 2020

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Reduced expression of odd‑skipped related transcription factor 1 promotes proliferation and invasion of breast cancer cells and indicates poor patient prognosis

Yuan Wang, Lei Lei, Fang Xu, Hong‑Tao Xu
Pages: 2946-2954
Published online on: 07 July 2020

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miR‑452‑5p and miR‑215‑5p expression levels in colorectal cancer tissues and their relationship with clinicopathological features

Jingbo Yan, Ru Wei, Hui Li, Yan Dou, Junhui Wang
Pages: 2955-2961
Published online on: 09 July 2020

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Article

Long non‑coding RNA‑ZNF281 upregulates PTEN expression via downregulation of microRNA‑221 in non‑small cell lung cancer

Xin Lu, Bin Yin, Xuekun Wang, Fengchan Wang, Yue Li, Na Wang, Xinai Yang, Wenqing Jiang
Pages: 2962-2968
Published online on: 07 July 2020

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Characterization and imaging of surgical specimens of invasive breast cancer and normal breast tissues with the application of Raman spectral mapping: A feasibility study and comparison with randomized single‑point detection method

Haipeng Zhang, Xiaozhen Wang, Rongbo Ding, Lishengnan Shen, Pin Gao, Hui Xu, Caifeng Xiu, Huanxia Zhang, Dong Song, Bing Han
Pages: 2969-2976
Published online on: 03 July 2020

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Article

Early response of bone metastases can predict tumor response in patients with non‑small‑cell lung cancer with bone metastases in the treatment with nivolumab

Eiji Nakata, Shinsuke Sugihara, Yoshifumi Sugawara, Toshiyuki Kozuki, Daijiro Harada, Naoyuki Nogami, Ryuichi Nakahara, Takayuki Furumatsu, Tomonori Tetsunaga, Toshiyuki Kunisada, Toshifumi Ozaki
Pages: 2977-2986
Published online on: 10 July 2020

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Article

Quantitative volumetric assessment of the solid portion percentage on CT images to predict ROS1/ALK rearrangements in lung adenocarcinomas

Jing Zheng, Jianya Zhou, Jinpeng Liu, Jingfeng Xu, Ke  Sun, Bo  Wang, He Cao, Wei Ding, Jianying Zhou
Pages: 2987-2996
Published online on: 06 July 2020

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Article Open Access

Inhibition of Rac1 reverses enzalutamide resistance in castration‑resistant prostate cancer Corrigendum in /10.3892/ol.2026.15523

Xiaoliang Chen, Lili Yin, Gan Qiao, Yanhua Li, Baoyuan Li, Yunfeng Bai, Feng Feng
Pages: 2997-3005
Published online on: 08 July 2020

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Article Open Access

Adenovirus‑mediated overexpression of interleukin‑21 regulates the development of oral squamous cell carcinoma in vitro

Hao Liu, Peng Liu, Di Sun, Dayuan Xing, Xiaoping Wang, Jinge Yang, Shengzhi Wang
Pages: 3006-3014
Published online on: 07 July 2020

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Article

MicroRNA‑574‑3p inhibits the malignant behavior of liver cancer cells by targeting ADAM28 Retraction in /10.3892/ol.2023.13973

Zhongming Zha, Fuxin Jia, Pingan Hu, Erhui Mai, Ting Lei
Pages: 3015-3023
Published online on: 10 July 2020

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Article

Long non‑coding RNA NBAT1 inhibits the progression of glioma through the miR‑21/SOX7 axis

Ning Guan, Rui Wang, Xu Feng, Chenguang Li, Wenshi Guo
Pages: 3024-3034
Published online on: 09 July 2020

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Article

Clinical outcomes and safety of apatinib monotherapy in the treatment of patients with advanced epithelial ovarian carcinoma who progressed after standard regimens and the analysis of the VEGFR2 polymorphism

Zhen Yan, Yuan‑Yuan Gu, Xiao‑Di Hu, Qun Zhao, Hai‑Li  Kang, Miao Wang, Wei Duan, Yin Guan
Pages: 3035-3045
Published online on: 10 July 2020

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Article

Comparison of the diagnostic value of CEA combined with OPN or DKK1 in non‑small cell lung cancer

Jinlin Sun, Xudong Chen, Yansen Wang
Pages: 3046-3052
Published online on: 09 July 2020

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Article

The combination of orlistat, lonidamine and 6‑diazo‑5‑oxo‑L‑norleucine induces a quiescent energetic phenotype and limits substrate flexibility in colon cancer cells

Alejandro Schcolnik‑Cabrera, Alma Chavez‑Blanco, Guadalupe Dominguez‑Gomez, Mandy Juarez, Donna Lai, Sheng Hua, Armando R. Tovar, Jose Diaz‑Chavez, Alfonso Duenas‑Gonzalez
Pages: 3053-3060
Published online on: 09 July 2020

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Correction Open Access

[Corrigendum] Characterization of an orthotopic gastric cancer mouse model with lymph node and organ metastases using bioluminescence imaging

Hai-Yi Feng, Yunpeng Zhang, Hai-Jun Liu, Xiao Dong, Si-Cong Yang, Qin Lu, Fanping Meng, Hong-Zhuan Chen, Peng Sun, Chao Fang
Pages: 3061-3061
Published online on: 10 July 2020

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Correction Open Access

[Corrigendum] Knockdown of pseudogene DUXAP8 expression in glioma suppresses tumor cell proliferation

Xu Zhao, Shuai Hao, Minqing Wang, Deguang Xing, Chengwei Wang
Pages: 3062-3062
Published online on: 10 July 2020

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

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Article Open Access

Early postoperative complications and patient‑reported quality of life following breast‑conserving surgery with intraoperative radiotherapy: A prospective cohort study

Hongmei Han, Xuwen Liu, Baozhong Zhang, Jingjing Liu, Jing Wang, Qingsong Pang
Article Number: 268
Published online on: 27 April 2026

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Exploring the mechanism of action of glaucocalyxin D against acute myeloid leukemia using network pharmacology, molecular docking and cellular experiments

Lian Chen, Weixian Yang, Weiqing Zhang, Heng Luo, Chen Yan
Article Number: 267
Published online on: 27 April 2026

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Review
Special Issue

Advances in cerebrospinal fluid biomarkers for the diagnosis, treatment and monitoring of leptomeningeal metastases (Review)

Huaixu Li, Wenwen Fan, Fengchun Mu, Cheng Fang, Ting Xiao, Jinghai Wan, Hongqing Cai
Article Number: 266
Published online on: 27 April 2026

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Article Open Access

Exploration of the effect and mechanism of Eclipta prostrata L. against gastric cancer based on network pharmacology and experimental verification

Weizhou Yu, Xiaohui Ni, Jing Wang, Wei Xia, Xinya Shen, Fan Qiu, Yuping Chen
Article Number: 265
Published online on: 27 April 2026

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Article Open Access

Neoadjuvant radiotherapy for resectable hepatocellular carcinoma with vascular invasion: A systematic review and meta‑analysis

Yuhao Su, Yuxin Liang, Deyuan Zhong, Hongtao Yan, Qinyan Yang, Xiaolun Huang
Article Number: 264
Published online on: 27 April 2026

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Article Open Access

Computational discovery of novel colony‑stimulating factor‑1 receptor as a potential therapeutic biomarker in osteosarcoma and a novel inhibitor from herbal sources

Hui Zhang, Shiwei Wu, Dan Luo, Jincai Guo
Article Number: 263
Published online on: 24 April 2026

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Article Open Access

Effect of the use of hormonal replacement therapy on breast cancer prognosis: A systematic review and meta‑analysis

Javier Angel Canelas Fernández, Jéssica Alonso‑Molero, Paz Rodríguez‑Cundín, Javier Llorca, Inés Gómez‑Acebo, Trinidad Dierssen‑Sotos
Article Number: 262
Published online on: 24 April 2026

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Article Open Access

Evaluation of smoking status as a prognostic factor under immune checkpoint inhibitor treatment: A single center analysis

Christoph Schaefers, Annika Poch, Anika Forstreuter, Frederike Bokemeyer, Carsten Bokemeyer, Christoph Seidel
Article Number: 261
Published online on: 24 April 2026

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Correction Open Access

[Corrigendum] CDDO, a PPAR‑γ ligand, inhibits TPA‑induced cell migration and invasion through a PPAR‑γ‑independent mechanism

Hye-Yeon Jang, On-Yu Hong, Hyun Jo Youn, Jaeuk Jung, Eun Yong Chung, Sung Hoo Jung, Jong-Suk Kim
Article Number: 260
Published online on: 24 April 2026

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Review Open Access

Dual roles of neutrophil extracellular traps in tumors: From pro‑metastatic mechanisms to immunotherapeutic strategies (Review)

Mingxin Guo, Han Wang, Jiaqi Zeng, Ning Wu, Zhiqiang Hu, Ao Xue, Ting Dai
Article Number: 259
Published online on: 23 April 2026

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Review Open Access

Emerging role of protein arginine methyltransferase 5 in gastrointestinal cancer (Review)

Rui Zhang, Yiwen Lu, Xiaohua Fang, Fengquan Zhang, Weidong Wu, Jie Song, Zhenzhen Liang
Article Number: 258
Published online on: 23 April 2026

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Case Report Open Access

Adjuvant immunotherapy plus chemotherapy and maintenance immunotherapy for pulmonary lymphoepithelioma‑like carcinoma with hepatitis B virus infection, KRAS mutation and high expression of programmed death ligand 1: A case report

Jing Zhu, Qing-Gui Xu, Jiao Zhu, Rui-Xiang Zhou, Yu-Chuan Zhou, Zhi-Ke Li
Article Number: 257
Published online on: 22 April 2026

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Retraction Open Access

[Retracted] Interleukin‑17 promotes the development of cisplatin resistance in colorectal cancer

Guolong Sui, Yingna Qiu, Haijuan Yu, Qingbin Kong, Baowen Zhen
Article Number: 256
Published online on: 22 April 2026

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Article Open Access

An m6A‑programmed cell death signature predicts prognosis and identifies STK25 as a therapeutic target in colon adenocarcinoma

Hezhi Yu, Tihui Li, Xiaoyun Huang, Zihan Chen, Zixiang Lin, Fenglin Chen
Article Number: 255
Published online on: 22 April 2026

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Article Open Access

METTL5 reprograms glycolytic metabolism and promotes non‑small cell lung cancer progression by modifying PGAM1

Yuchen Shan, Xiaoyu Duan, Kai Yuan, Ming Lou, Qiyong Wu, Zhaojia Gao
Article Number: 254
Published online on: 20 April 2026

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Article Open Access

Clinical features and outcomes of peripheral T‑cell lymphoma, not otherwise specified: A single institution retrospective analysis of 30 cases

Meng-Xue Ma, Ya-Li Zhang, Li-Na Xing, Qiu-Yi Wang, Shukai Qiao
Article Number: 253
Published online on: 20 April 2026

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Article Open Access

BUD23 is associated with malignancy and correlates with immune infiltration in NSCLC

Yonghuang Tan, Jun Ma, Jiangli Zhou, Jianjun Lu
Article Number: 252
Published online on: 20 April 2026

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Article Open Access

Evaluation of NID2 and CDO1 methylation for ovarian cancer screening

Shuilian Wu, Jing Jin, Yuanyuan Cao, Xiaofan He, Qiang Hou, Mingfeng Jiang
Article Number: 251
Published online on: 20 April 2026

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Retraction Open Access

[Retracted] Improved ataxia telangiectasia mutated kinase inhibitor KU60019 provides a promising treatment strategy for non‑invasive breast cancer

Ying Zhu, Changfei Mao, Jianzhong Wu, Shuchun Li, Rong Ma, Haixia Cao, Minghua Ji, Changwen Jing, Jinhai Tang
Article Number: 250
Published online on: 20 April 2026

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Case Report Open Access

Fever and leukemoid reaction in bladder cancer: A case report

Tianrun Huang, Jiguo Xu, Yuwei He, Yu Shen, Chenlong Chu, Jingyuan Lu, Parehe Alimu, Chunlei Chen, Jianhe Liu
Article Number: 249
Published online on: 20 April 2026

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Article Open Access

Prognostic effect and prognostic factors of TACE for the treatment of unresectable hepatocellular carcinoma: Propensity score matching analysis

Liangliang Zhang, Cancan Li, Hui Guo, Xue Zhang, Wei Liu, Xing Xu
Article Number: 248
Published online on: 16 April 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA BX357664 inhibits cell proliferation and metastasis in human lung cancer

Shu-Hui Xiao, Gong-Xiang Li, Lingli Quan
Article Number: 247
Published online on: 16 April 2026

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Article

Safety and feasibility of total neoadjuvant FLOT chemotherapy in locally‑advanced gastric and gastroesophageal junction cancer

Oleksii Dobrzhanskyi, Andrii Horodetskyi, Mykyta Pepenin, Yurii Kondratskyi
Article Number: 246
Published online on: 16 April 2026

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Article Open Access

Vasculogenic mimicry and breast cancer prognosis: Insights into predictive model development

Zhifeng Wu, Yueyue Teng, Shengchao Huang, Shiming Shi, Pu Qiu, Leyao Shan, Meihua Lin, Yuanqi Zhang
Article Number: 245
Published online on: 15 April 2026

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Article Open Access

Effect and safety analysis of raltitrexed peritoneal perfusion in patients with intermediate and advanced colorectal cancer

Yanhua Wan, Xiaoyun Dai, Liang Chao
Article Number: 244
Published online on: 15 April 2026

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Article Open Access

Mechanism of action of alkaloids in Fritillaria‑induced autophagy and apoptosis in non‑small cell lung cancer

Mengru Teng, Mengrui Zhang, Jun He, Wai Ming Tse, Kathy Wai Gaun Tse, Chengwu Liu, Bengui Ye
Article Number: 243
Published online on: 15 April 2026

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Article Open Access

Identification of a prognostic model using immune related genes combined with tumour mutational burden and T cell infiltration in triple‑negative breast cancer

You Meng, Ze-Xin Han, Jie Zhu, Ying Wang, Yue-Qing Huang, Zhong-Hua Zou, Yu-Yuan Ma, Yi-Fan Li, Han Wang, Ying Li, Lian Lian, Wen-Jie Wang
Article Number: 242
Published online on: 15 April 2026

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Correction Open Access

[Corrigendum] Silencing glioma‑associated oncogene homolog 1 suppresses the migration and invasion of hepatocellular carcinoma in vitro

Zeming Hu, Fangfang Xie, Ang Hu, Mengjing Xu, Yuwen Liu, Jiankang Zhang, Jianbo Xiao, Yunlei Song, Jianing Zhong, Bin Chen
Article Number: 241
Published online on: 15 April 2026

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Article

A novel inflammation and tumor marker‑based prognostic score, neutrophil‑lymphocyte ratio‑C‑reactive protein‑Ca19‑9, in metastatic gastric cancer

Berkan Karabuğa, Osman Bilge Kaya, Ekin Konca Karabuğa, Ergin Aydemir, Mehmet Emin Yilmaz, Sedef Tatar Bolat, Ayşegül Uçkun, Enes Kaptan, Öztürk Ateş, Mustafa Büyükkör
Article Number: 240
Published online on: 15 April 2026

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Article Open Access

KRAS (G12D)‑selective inhibitor MRTX1133 suppresses proliferation and differentially modulates chemosensitivity in ovarian mucinous carcinoma

Ryota Watano, Hiroaki Mizukami, Yasushi Saga
Article Number: 239
Published online on: 15 April 2026

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Article

Intensity‑ and time‑dependent anticancer effects of alternating electric fields in non‑small cell lung cancer cell lines

Jinju Heo, Myonggeun Yoon
Article Number: 238
Published online on: 15 April 2026

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Review Open Access

KLF family of proteins in gastrointestinal tumors (Review)

Jingjing Zhang, Rupu Zhao, Pengjie Yang, Yong Zhu, Benben Zhu
Article Number: 237
Published online on: 15 April 2026

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Article

Establishment and validation of a diagnostic model for evaluating synchronous liver metastasis in pancreatic cancer using comprehensive blood biochemical indicators

Yiyi Jiang, Gaoyao Peng, Songqing He, Jiangfa Li
Article Number: 236
Published online on: 14 April 2026

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Review Open Access

Soluble isoforms of EGFR family in breast cancer: Advances and clinical relevance (Review)

Peng Yang, Xinnong Jiang, Fangguo He
Article Number: 235
Published online on: 14 April 2026

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Article Open Access

Thrombospondin‑1 triggers calreticulin expression in human mucoepidermoid carcinoma MC‑3 cells via the PERK/CHOP pathway

Shengwei Bao, Yuanyuan Zhu, Lijuan Guo, Sen Yang
Article Number: 234
Published online on: 14 April 2026

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Article Open Access

Unveiling the prognostic and immunotherapeutic role of Tregs in lung cancer using integrated analysis of single‑cell and bulk RNA‑sequencing

Hongwei He, Zhiming Xiao, Jijun Xue, Yu Zhang, Jichen Qu, Peng Wu, Qiangjun He
Article Number: 233
Published online on: 14 April 2026

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Review Open Access

Nobiletin in cancer therapy: Emerging insights into multi-target mechanisms, overcoming drug resistance and therapeutic translation (Review)

Yanfang Zhang, Qingcai Li, Wenbin Yu, Bin He, Jiahua Peng, Bin Yao
Article Number: 232
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF‑κB pathway

Wen-Yue Liu, Xu Wu, Cheng-Quan Liao, Jie Shen, Jun Li
Article Number: 231
Published online on: 14 April 2026

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Article

Pretreatment C‑reactive protein‑triglyceride‑glucose index predicts survival in patients with FLOT‑treated locally advanced gastric and gastroesophageal junction cancer

Ayşegül Dumludağ, Mehmet Torun, Osman Sütçüoğlu
Article Number: 230
Published online on: 09 April 2026

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Case Report

Intravascular large B‑cell lymphoma mimicking an orbital mass lesion and bilateral cavernous sinus syndrome: A case report

Qiong Wu, Yiran Jia, Bentao Yang, Xiaojin He, Hongjuan Liu, Libin Jiang
Article Number: 229
Published online on: 09 April 2026

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Correction Open Access

[Corrigendum] FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo

Kun Zhao, Jie Gao, Jihua Shi, Chengcheng Shi, Chun Pang, Jie Li, Wenzhi Guo, Shuijun Zhang
Article Number: 228
Published online on: 09 April 2026

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Role of CDX2 in the prognosis of colorectal cancer across stages 0‑IV

Guojun Tong, Hai Qian, Yuefeng Fei, Sheng Yu, Kun Guo, Wenwen Yu, Jing Li, Sicheng Yan
Article Number: 227
Published online on: 08 April 2026

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Exploring multiple biomarkers and constructing ferroptosis‑associated competing endogenous RNA networks as dual targets in retinoblastoma

Zhengjia Kang, Gaoqin Liu
Article Number: 226
Published online on: 08 April 2026

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Review Open Access

Role of mesenchymal stem cells and their derived exosomes in cervical cancer: Bidirectional mechanisms and research progress (Review)

Xue Li, Daqing Wang
Article Number: 225
Published online on: 08 April 2026

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Review Open Access

Hypoxia‑inducible factors: Regulatory functions and status as a therapeutic target in gastric cancer (Review)

Jia Xu, Guangzhi Ding, Yiming Wang, Chang Liu
Article Number: 224
Published online on: 08 April 2026

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Article Open Access

Machine learning‑based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer

Nan Wu, Zhongting Fan
Article Number: 223
Published online on: 08 April 2026

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Article Open Access

Assessing the density of lymph node metastasis in various inguinal regions of penile cancer using the nine‑section method: A prospective study

Chen Hu, Longguo Dai, Hongyi Wu, Yu Bai, Jun Li, Haiyang Jiang, Haoli Yin, Ying Bi, Wenzhao Wu, Ruiqian Li, Hong Shi
Article Number: 222
Published online on: 08 April 2026

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Article Open Access

Overexpression and knockdown of 5‑lipoxygenase regulates the migration and invasion of colorectal cancer cells

Xuyang Li, Jiletu Huge, Xiaoling Wang, Jing Zhou, Xiudan Li, Xiaoyan Gao, Tiewei Shi, Chunying Bai
Article Number: 221
Published online on: 08 April 2026

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Case Report

Targeting TROP‑2 in treatment‑resistant non‑small cell lung cancer harboring the KRAS G12C mutation and TROP‑2 upregulation: A case report

Lu Sun, Ying Xiong, Xiaobing Li, Yi Peng
Article Number: 220
Published online on: 08 April 2026

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Article Open Access

Exosomal‑miR‑32‑5p directly targets FOXN2 to regulate the proliferation, migration and apoptosis of uterine corpus endometrial carcinoma via the PI3K/AKT/BCL‑2 pathway

Xin Chen, Huihui Li, Xiang Cheng, Yirong Cai, Guangyi Guo
Article Number: 219
Published online on: 08 April 2026

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Expression of Concern Open Access

[Expression of Concern] PRKACB is downregulated in non‑small cell lung cancer and exogenous PRKACB inhibits proliferation and invasion of LTEP‑A2 cells

Yong Chen, Ying Gao, Ye Tian, Da-Li Tian
Article Number: 218
Published online on: 07 April 2026

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Review Open Access

Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Guiyang Tang, Hanrong Zuo, Rou Long, Chaohui Zhang, Yufan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo
Article Number: 217
Published online on: 02 April 2026

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Case Report Open Access

Comprehensive treatment for intracranial invasive sinonasal intestinal‑type adenocarcinoma with a focus on radiotherapy dosage and immunological combination therapy: A case report

Lianlian Yang, Qian Zhao, Fang Yi, Wenyan Guo, Qiongwen Zhang, Song Zhou, Dong Li, Zhihui Li
Article Number: 216
Published online on: 02 April 2026

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Review Open Access

Biological basis and clinical translation prospects of circulating cell‑free DNA in precision management of breast cancer (Review)

Li-Zhuang Fan, Ai-Lan Xu, Ya-Ru Xu, Luo Yang, Fang Yuan, Xin Nie
Article Number: 215
Published online on: 02 April 2026

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Review Open Access

Cutting‑edge advances in endocrine therapy for breast cancer (Review)

Yumei Dong, Lihua Shao, Qiong Li, Yuexiao Qi, Tingting Liu, Shihong Wei, Haiyan Qi
Article Number: 214
Published online on: 02 April 2026

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Case Report Open Access

Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report

Mingrui Zhang, Huanfang Fan, Chunxia Sun, Dehui Li, Jiangya Gan, Yun He, Jiaqi Chen
Article Number: 213
Published online on: 02 April 2026

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Article Open Access

Dynamic curve type serves as an effective tool for the diagnosis of benign or malignant non‑mass enhancements on breast MRI

Tara Farooq Kareem, Areege Mustafa Kamal, Munawar Al Nakash
Article Number: 212
Published online on: 02 April 2026

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Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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July-2026 Volume 32 Issue 1

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review

Cancer stem cells and their molecular signaling mechanisms in tongue squamous cell carcinoma (Review)

Xuqiang Guo, Xuan Zhou, Wen Ran, Qiao Zhu, Wei Chen, Chengcheng Ma
Article Number: 313
Published online on: 25 May 2026

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Article Open Access

Pathological response and tumor regression grading following neoadjuvant chemo‑immunotherapy and chemotherapy in resectable non‑small cell lung cancer

Özge Kaya Korkmaz, Yaren Sari Çataldaş, Nazlican Saltik Barel, Mehmet Büyükevli
Article Number: 312
Published online on: 22 May 2026

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Article Open Access

D‑salicin induces oxidative stress‑mediated ERK1/2 suppression and apoptosis in endometrial cancer cells

Neziha Senem Ari, Ayşe Çakir Gündoğdu
Article Number: 311
Published online on: 22 May 2026

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Article Open Access

Decoding the role of polyamine metabolism in lung adenocarcinoma prognosis: A triangulated approach combining transcriptome, single‑cell and Mendelian randomization analyses

Hua Yang, Lemeng Zhang, Jianhua Chen, Junjie Zhang
Article Number: 310
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu
Article Number: 309
Published online on: 21 May 2026

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Review Open Access

Targeting non‑small cell lung cancer: Molecular mechanisms and clinical studies (Review)

Ying Luo, Guofang Yin, Xiaoqin Luo, Yue Liu, Kaiyu Jin, Zhiguo Wang
Article Number: 308
Published online on: 20 May 2026

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Article Open Access

Histopathological changes in primary extramammary Paget disease with emphasis on syringomatous structures and syringocystadenocarcinoma papilliferum in situ‑like changes

Yutaro Fukuma, Mitsuaki Ishida, Yoshinobu Hirose
Article Number: 307
Published online on: 20 May 2026

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Case Report Open Access

Durable response to selpercatinib in HOOK3‑RET fusion positive, α‑fetoprotein producing metastatic pancreatic ductal adenocarcinoma with intestinal‑type differentiation

Harsahib Singh Sandhu, Aparna Natarajan, Smiley Joshi
Article Number: 306
Published online on: 20 May 2026

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Correction Open Access

[Corrigendum] PVT1 promotes resistance to 5‑FU in colon cancer via the miR‑486‑5p/CDK4 axis

Zhuhe Luo, Ruijun Chen, Shen Hu, Xibin Huang, Zhenyi Huang
Article Number: 305
Published online on: 20 May 2026

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Case Report Open Access

Pelvic schwannoma misdiagnosed as colorectal cancer metastasis and the corresponding diagnostic lessons: A report of two cases

Shilong Wang, Kaixiang Zhang, Xiangwu Lin, Feilai Xie, Jian Yang, Jie Li
Article Number: 304
Published online on: 19 May 2026

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Case Report

Multidetector computed tomography detection of perineural infiltration around the superior mesenteric artery in intrahepatic cholangiocarcinoma: A case report

Myeong Hun Oh, Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Suk Kim, Nam Kyung Lee, Seung Baek Hong
Article Number: 303
Published online on: 19 May 2026

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Review Open Access

Clinical implications of lactylation modification in digestive system tumors (Review)

Lin Pan, Fengye Liu, Wenjing Yu
Article Number: 302
Published online on: 19 May 2026

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Article Open Access

Rare BRCA1 c.3418_3419insTGACTACT:p.S1140Mfs*18 germline mutation in a family with breast and ovarian cancer

Chao Zhai, Long Jia, Chaoyang Wang, Liang Chen, Tuo Han, Dong Xiao
Article Number: 301
Published online on: 19 May 2026

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Expression of Concern Open Access

[Expression of Concern] miR‑148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer

Wei Zhao, Jianbao Zheng, Guangbing Wei, Kui Yang, Guanghui Wang, Xuejun Sun
Article Number: 300
Published online on: 19 May 2026

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Article Open Access

Prognostic significance of squamous differentiation in pT2N0 urothelial bladder cancer

Alper Coskun, Ahmet Bilgehan Sahin, Selva Kabul, Mehmet Emin Dagtekin, Seda Sali, Buket Erkan Ozmarasali, Adem Deligonul, Erdem Cubukcu, Meral Kurt, Gursel Savci, Turkkan Evrensel, Ismet Yavascaoglu
Article Number: 299
Published online on: 18 May 2026

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Article

Jaceosidin inhibits cell viability and induces apoptosis in non‑small cell lung cancer by inhibiting the Ras/Raf/MEK/ERK and Akt pathways

Xiaodie Cao, Chong Ma, Xin Wang, Cui Wang, Lanlin Shen, Jingru Wei, Rongmin Yang, Yan Li, Xu He, Li Chen
Article Number: 298
Published online on: 18 May 2026

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Review Open Access

Ubiquitination and N6‑methyladenosine in cancer: Convergent regulation of oncogenic signaling pathways (Review)

Hailong Li, Xuelin Lu
Article Number: 297
Published online on: 18 May 2026

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Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 296
Published online on: 15 May 2026

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Case Report Open Access

Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu
Article Number: 293
Published online on: 13 May 2026

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Article Open Access

Gastrointestinal cancer with indeterminate 18F‑FDG PET/CT findings: Diagnostic efficacy analysis of 68Ga‑FAPI‑04 PET/MRI

Jingxuan Miao, Yifei Xu, Feng Qiao, Ni Chen, Muhammad Imran Khan, Ye Zhao, Hui Wang
Article Number: 292
Published online on: 13 May 2026

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Article Open Access

Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu
Article Number: 291
Published online on: 13 May 2026

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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