Open Access

Research progress regarding the role of long non‑coding RNAs in osteosarcoma (Review)

  • Authors:
    • Yanli Zhang
    • Yanchuan Pu
    • Jin Wang
    • Zicai Li
    • Hulin Wang
  • View Affiliations

  • Published online on: July 3, 2020     https://doi.org/10.3892/ol.2020.11807
  • Pages: 2606-2612
  • Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Osteosarcoma is a malignant tumor that occurs in children and adolescents. Although treatments for osteosarcoma have improved, the likelihood of survival remains low for most patients with metastasis and recurrence. Elucidating the mechanism underlying the development of osteosarcoma and chemotherapy resistance will be important to improve diagnosis and treatment. Long non‑coding RNAs (lncRNAs), which are longer than 200 nucleotides in length and do not encode for proteins, have been shown to play a regulatory role in the occurrence and development of osteosarcoma, and are expected to serve as biomarkers and molecular targets. This review discusses the progress in the study of the role of lncRNAs in osteosarcoma, and highlights the recent developments in this field.

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September-2020
Volume 20 Issue 3

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Zhang Y, Pu Y, Wang J, Li Z and Wang H: Research progress regarding the role of long non‑coding RNAs in osteosarcoma (Review) . Oncol Lett 20: 2606-2612, 2020
APA
Zhang, Y., Pu, Y., Wang, J., Li, Z., & Wang, H. (2020). Research progress regarding the role of long non‑coding RNAs in osteosarcoma (Review) . Oncology Letters, 20, 2606-2612. https://doi.org/10.3892/ol.2020.11807
MLA
Zhang, Y., Pu, Y., Wang, J., Li, Z., Wang, H."Research progress regarding the role of long non‑coding RNAs in osteosarcoma (Review) ". Oncology Letters 20.3 (2020): 2606-2612.
Chicago
Zhang, Y., Pu, Y., Wang, J., Li, Z., Wang, H."Research progress regarding the role of long non‑coding RNAs in osteosarcoma (Review) ". Oncology Letters 20, no. 3 (2020): 2606-2612. https://doi.org/10.3892/ol.2020.11807