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Article Open Access

Application of additive manufacturing in customized titanium mandibular implants for patients with oral tumors

  • Authors:
    • Yan Xia
    • Zhi Chao Feng
    • Changchun Li
    • Heming Wu
    • Chunbo Tang
    • Lihua Wang
    • Hongwei Li
  • View Affiliations / Copyright

    Affiliations: Jiangsu Key Laboratory of Oral Disease, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China, Rutgers School of Dental Medicine, Rutgers University, Newark, NJ 07103, USA, Department of Stomatology, The Second Hospital of Nanjing, Nanjing, Jiangsu 210003, P.R. China, AK Medical Holdings Limited, Beijing 100101, P.R China
    Copyright: © Xia et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 51
    |
    Published online on: July 27, 2020
       https://doi.org/10.3892/ol.2020.11912
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Abstract

The application of additive manufacturing (AM) technology has been widely used in various medical fields, including craniomaxillofacial surgery. The aim of the present study was to examine the surgical efficiency and post‑operative outcomes of patient‑specific titanium mandibular reconstruction using AM. Major steps in directly designing and manufacturing 3D customized titanium implants are discussed. Furthermore, pre‑operative preparations, surgical procedures and post‑operative treatment outcomes were compared among patients who received mandibular reconstruction using a customized 3D titanium implant, titanium reconstruction plates or vascularized autologous fibular grafting. Use of a customized titanium implant significantly improved surgical efficiency and precision. When compared with mandibular reconstruction using the two conventional approaches, patients who received the customized implant were significantly more satisfied with their facial appearance, and exhibited minimal post‑operative complications in the 12‑month follow‑up period. Patients who underwent mandibular reconstruction using a customized titanium implant displayed improved mandibular contour symmetry, restored occlusal function, normal range of mouth opening and no temporomandibular joint related pain; all complications frequently experienced by patients who undergo conventional approaches of mandibular reconstruction.
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Copy and paste a formatted citation
Spandidos Publications style
Xia Y, Feng Z, Li C, Wu H, Tang C, Wang L and Li H: Application of additive manufacturing in customized titanium mandibular implants for patients with oral tumors. Oncol Lett 20: 51, 2020.
APA
Xia, Y., Feng, Z., Li, C., Wu, H., Tang, C., Wang, L., & Li, H. (2020). Application of additive manufacturing in customized titanium mandibular implants for patients with oral tumors. Oncology Letters, 20, 51. https://doi.org/10.3892/ol.2020.11912
MLA
Xia, Y., Feng, Z., Li, C., Wu, H., Tang, C., Wang, L., Li, H."Application of additive manufacturing in customized titanium mandibular implants for patients with oral tumors". Oncology Letters 20.4 (2020): 51.
Chicago
Xia, Y., Feng, Z., Li, C., Wu, H., Tang, C., Wang, L., Li, H."Application of additive manufacturing in customized titanium mandibular implants for patients with oral tumors". Oncology Letters 20, no. 4 (2020): 51. https://doi.org/10.3892/ol.2020.11912
Copy and paste a formatted citation
x
Spandidos Publications style
Xia Y, Feng Z, Li C, Wu H, Tang C, Wang L and Li H: Application of additive manufacturing in customized titanium mandibular implants for patients with oral tumors. Oncol Lett 20: 51, 2020.
APA
Xia, Y., Feng, Z., Li, C., Wu, H., Tang, C., Wang, L., & Li, H. (2020). Application of additive manufacturing in customized titanium mandibular implants for patients with oral tumors. Oncology Letters, 20, 51. https://doi.org/10.3892/ol.2020.11912
MLA
Xia, Y., Feng, Z., Li, C., Wu, H., Tang, C., Wang, L., Li, H."Application of additive manufacturing in customized titanium mandibular implants for patients with oral tumors". Oncology Letters 20.4 (2020): 51.
Chicago
Xia, Y., Feng, Z., Li, C., Wu, H., Tang, C., Wang, L., Li, H."Application of additive manufacturing in customized titanium mandibular implants for patients with oral tumors". Oncology Letters 20, no. 4 (2020): 51. https://doi.org/10.3892/ol.2020.11912
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