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Therapeutic pattern and progress of neoadjuvant treatment for triple‑negative breast cancer (Review)

  • Authors:
    • Yan Xiao
    • Wencheng Gao
  • View Affiliations / Copyright

    Affiliations: Department of Oncology, Dongguan Tungwah Hospital, Dongguan, Guangdong 523000, P.R. China, Department of General Surgery, Dongguan Houjie Town People's Hospital, Dongguan, Guangdong 523962, P.R. China
    Copyright: © Xiao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 219
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    Published online on: May 19, 2022
       https://doi.org/10.3892/ol.2022.13340
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Abstract

Triple‑negative breast cancer (TNBC) is a heterogeneous disease, accounting for about 15.0‑20.0% of all breast cancer cases. TNBC is associated with early recurrence and metastasis, strong invasiveness and a poor prognosis. Chemotherapy is currently the mainstay of treatment for TNBC, and achievement of a pathological complete response is closely associated with a long‑term good prognosis. Improving the long‑term prognosis in patients with TNBC is a challenge in breast cancer treatment, and more clinical evidence is needed to guide the choice of treatment strategies. The current study reviews the conventional treatment modality for TNBC and the selection of neoadjuvant chemotherapy (NACT) regimens available. The research progress on optimizing NACT regimens is also reviewed, and the uniqueness of the treatment of this breast cancer subtype is emphasized, in order to provide reference for the clinical practice and research with regard to TNBC treatment.
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Copy and paste a formatted citation
Spandidos Publications style
Xiao Y and Gao W: Therapeutic pattern and progress of neoadjuvant treatment for triple‑negative breast cancer (Review). Oncol Lett 24: 219, 2022.
APA
Xiao, Y., & Gao, W. (2022). Therapeutic pattern and progress of neoadjuvant treatment for triple‑negative breast cancer (Review). Oncology Letters, 24, 219. https://doi.org/10.3892/ol.2022.13340
MLA
Xiao, Y., Gao, W."Therapeutic pattern and progress of neoadjuvant treatment for triple‑negative breast cancer (Review)". Oncology Letters 24.1 (2022): 219.
Chicago
Xiao, Y., Gao, W."Therapeutic pattern and progress of neoadjuvant treatment for triple‑negative breast cancer (Review)". Oncology Letters 24, no. 1 (2022): 219. https://doi.org/10.3892/ol.2022.13340
Copy and paste a formatted citation
x
Spandidos Publications style
Xiao Y and Gao W: Therapeutic pattern and progress of neoadjuvant treatment for triple‑negative breast cancer (Review). Oncol Lett 24: 219, 2022.
APA
Xiao, Y., & Gao, W. (2022). Therapeutic pattern and progress of neoadjuvant treatment for triple‑negative breast cancer (Review). Oncology Letters, 24, 219. https://doi.org/10.3892/ol.2022.13340
MLA
Xiao, Y., Gao, W."Therapeutic pattern and progress of neoadjuvant treatment for triple‑negative breast cancer (Review)". Oncology Letters 24.1 (2022): 219.
Chicago
Xiao, Y., Gao, W."Therapeutic pattern and progress of neoadjuvant treatment for triple‑negative breast cancer (Review)". Oncology Letters 24, no. 1 (2022): 219. https://doi.org/10.3892/ol.2022.13340
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