Open Access

Role of exosomes in cellular communication between tumor cells and the tumor microenvironment (Review)

  • Authors:
    • Qiao Li
  • View Affiliations

  • Published online on: May 31, 2022     https://doi.org/10.3892/ol.2022.13360
  • Article Number: 240
  • Copyright: © Li et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Exosomes are nanovesicles secreted by almost all types of cells. They contain RNAs, microRNAs, proteins and other bioactive substances, and can be used as carriers and for communication between cells. They regulate numerous biological processes, such as tumor development, cell proliferation and resistance to chemotherapy. Exosome‑mediated communication between tumor cells and the tumor microenvironment (TME) is crucial in the initiation and progression of tumor development. The present review aims to summarize the role of exosomes in mediating the communication between tumor cells and the TME and to suggest the potential use of exosomes as targets for the development of novel therapeutic strategies against cancer.

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July-2022
Volume 24 Issue 1

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Li Q: Role of exosomes in cellular communication between tumor cells and the tumor microenvironment (Review). Oncol Lett 24: 240, 2022
APA
Li, Q. (2022). Role of exosomes in cellular communication between tumor cells and the tumor microenvironment (Review). Oncology Letters, 24, 240. https://doi.org/10.3892/ol.2022.13360
MLA
Li, Q."Role of exosomes in cellular communication between tumor cells and the tumor microenvironment (Review)". Oncology Letters 24.1 (2022): 240.
Chicago
Li, Q."Role of exosomes in cellular communication between tumor cells and the tumor microenvironment (Review)". Oncology Letters 24, no. 1 (2022): 240. https://doi.org/10.3892/ol.2022.13360