Open Access

Delayed pulmonary metastasis and recurrence of intracranial malignant solitary fibrous tumor/hemangiopericytoma: Case report and literature review

  • Authors:
    • Qiheng Li
    • Chunmei Zhang
    • Zhengjin Li
  • View Affiliations

  • Published online on: June 14, 2022     https://doi.org/10.3892/ol.2022.13375
  • Article Number: 255
  • Copyright: © Li et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Solitary fibrous tumors/hemangiopericytomas (SFTs/HPCs) are intracranial spindle cell tumors that originate from interstitial tissue. SFTs/HPCs that are primary malignant intracranial tumors are exceedingly uncommon. A case of intracranial malignant SFT/HPC that originated intracranially and spread to the pulmonary region is described herein. Furthermore, the specimens from two surgical resections obtained when the patient had undergone two prior procedures for intracranial ‘meningiomas’ were also reviewed. The results of the lung biopsy matched the morphologic appearance of the intracranial tumor. The patient died ~2 years after the chest pain started. In addition, the literature was reviewed. According to previous studies, STAT6 expression was positive in 100% of SFTs/HPCs and radiologic characteristics assisted in determining the tumor pathology and grade. Surgical management has been the mainstay treatment for SFTs. In cases of incomplete resection, adjuvant radiotherapy is effective and rigorous follow‑up is required to monitor for recurrence.
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August-2022
Volume 24 Issue 2

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Li Q, Zhang C and Li Z: Delayed pulmonary metastasis and recurrence of intracranial malignant solitary fibrous tumor/hemangiopericytoma: Case report and literature review. Oncol Lett 24: 255, 2022
APA
Li, Q., Zhang, C., & Li, Z. (2022). Delayed pulmonary metastasis and recurrence of intracranial malignant solitary fibrous tumor/hemangiopericytoma: Case report and literature review. Oncology Letters, 24, 255. https://doi.org/10.3892/ol.2022.13375
MLA
Li, Q., Zhang, C., Li, Z."Delayed pulmonary metastasis and recurrence of intracranial malignant solitary fibrous tumor/hemangiopericytoma: Case report and literature review". Oncology Letters 24.2 (2022): 255.
Chicago
Li, Q., Zhang, C., Li, Z."Delayed pulmonary metastasis and recurrence of intracranial malignant solitary fibrous tumor/hemangiopericytoma: Case report and literature review". Oncology Letters 24, no. 2 (2022): 255. https://doi.org/10.3892/ol.2022.13375