Open Access

Mechanism of action of CTRP6 in the regulation of tumorigenesis in the digestive system (Review)

  • Authors:
    • Aimin Zhang
    • Mowei Kong
    • Xiuyun Zhang
    • Zhenying Pei
  • View Affiliations

  • Published online on: September 21, 2022     https://doi.org/10.3892/ol.2022.13511
  • Article Number: 391
  • Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Tumors of the digestive system have always received attention, and their occurrence and development are regulated by various mechanisms such as inflammation and immunity, glucose and lipid metabolism, and tumor angiogenesis. Complement Clq/TNF‑related protein 6 (CTRP6) is a member of the CTRP family; it is widely expressed in various tissues and cell types, and plays a biological role in a number of mechanisms, such as glucose and lipid metabolism and inflammation. Recent studies have revealed the tumor‑promoting effect of CTRP6 in gastric cancer, liver cancer, colorectal cancer and other gastrointestinal tumors, but, to the best of our knowledge, there has been no systematic discussion on the tumor‑promoting mechanism of CTRP6. The present study reviews the role of CTRP6 in tumors of the digestive system and its possible mechanisms.
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November-2022
Volume 24 Issue 5

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Zhang A, Kong M, Zhang X and Pei Z: Mechanism of action of CTRP6 in the regulation of tumorigenesis in the digestive system (Review). Oncol Lett 24: 391, 2022
APA
Zhang, A., Kong, M., Zhang, X., & Pei, Z. (2022). Mechanism of action of CTRP6 in the regulation of tumorigenesis in the digestive system (Review). Oncology Letters, 24, 391. https://doi.org/10.3892/ol.2022.13511
MLA
Zhang, A., Kong, M., Zhang, X., Pei, Z."Mechanism of action of CTRP6 in the regulation of tumorigenesis in the digestive system (Review)". Oncology Letters 24.5 (2022): 391.
Chicago
Zhang, A., Kong, M., Zhang, X., Pei, Z."Mechanism of action of CTRP6 in the regulation of tumorigenesis in the digestive system (Review)". Oncology Letters 24, no. 5 (2022): 391. https://doi.org/10.3892/ol.2022.13511