Primary epithelioid hemangioendothelioma of the eyelid: A case report

Chen,Lijiang; Han,Feng; Yang,Junjie; Huang,Bin; Liu,Hongsheng

doi:10.3892/ol.2022.13518

November-2022 Volume 24 Issue 5

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November-2022 Volume 24 Issue 5

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Case Report Open Access

Primary epithelioid hemangioendothelioma of the eyelid: A case report

Authors:
- Lijiang Chen
- Feng Han
- Junjie Yang
- Bin Huang
- Hongsheng Liu
View Affiliations / Copyright

Affiliations: Department of Pathology, The First People's Hospital of Xiaoshan District, Hangzhou, Zhejiang 311200, P.R. China, Department of Pathology, The Third People's Hospital of Xiaoshan District, Hangzhou, Zhejiang 311200, P.R. China

Copyright: © Chen et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Article Number: 398
|
Published online on: September 21, 2022

https://doi.org/10.3892/ol.2022.13518
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Abstract

Eyelid epithelioid hemangioendothelioma (EHE) is uncommon. The present study reports the clinical, histopathological and immunohistochemical characteristics of a 10‑year‑old girl with EHE and reviews the related literature. The patient was admitted with a painless red mass on the left eyelid, which had been present for 6 months. Under the microscope, tumor cells from the surgical specimen were composed of epithelioid cells (70%) and spindle cells (30%). The cytoplasm was eosinophilic, and some areas of the cytoplasm showed signet ring‑like or vacuolization changes. The presence of red blood cells could be seen in the luminal part of the primary blood vessel. Immunohistochemical results showed that the tumor cells were positive for CD34 and CD31, and the Ki‑67 proliferation index was 3%. As the first resection margin was positive, recurrence occurred 3 months after surgery, Therefore, patients with such tumors should undergo full resections to ensure a negative margin to prevent recurrence.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Primary epithelioid hemangioendothelioma of the eyelid: A case report

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