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Clinical characteristics of second primary malignancies among first primary malignancy survivors: A single‑center study, 2005‑2020

  • Authors:
    • Fenghao Geng
    • Minghua Liu
    • Jianhui Chen
    • Yanli Ge
    • Shuxia Wei
    • Fengyu Li
    • Chunsong Yang
    • Jianwei Sun
    • Lijing Gou
    • Jianyu Zhang
    • Shaokai Tang
    • Yi Wan
    • Jingyue Yang
    • Jie Zhang
  • View Affiliations / Copyright

    Affiliations: Laboratory of Radiation Medicine, West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China, Department of Pharmacy, The Hospital of 81st Group Army People's Liberation Army, Zhangjiakou, Hebei 075000, P.R. China, Department of Radiation Medicine, West China School of Basic Medical Sciences and Forensic Medicine, Sichuan University, Chengdu, Sichuan 610041, P.R. China, Department of Oncology, The Hospital of 81st Group Army People's Liberation Army, Zhangjiakou, Hebei 075000, P.R. China, Department of Pharmacy, West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China, Department of Health Services, Xijing Hospital, Air Force Military Medical University, Xi'an, Shaanxi 710032, P.R. China, Department of Oncology, Xijing Hospital, Air Force Military Medical University, Xi'an, Shaanxi 710032, P.R. China, Department of Radiation Medicine, Air Force Military Medical University, Xi'an, Shaanxi 710032, P.R. China
    Copyright: © Geng et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 24
    |
    Published online on: November 23, 2022
       https://doi.org/10.3892/ol.2022.13610
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Abstract

The cancer survivor population is growing due to advances in detection and treatment. For improved long‑term patient management, it is critical to examine the clinical characteristics and outcomes of second primary malignancies (SPMs). An SPM is defined as a second distinct pathological diagnosis, with the same or different origin as the first primary malignancy (FPM). In the present retrospective study, categorical clinical variables were compared between subgroups and the impact on overall survival was evaluated. A total of 1,188 patients with an FPM were included, of which 102 experienced an SPM (8.59%). When compared with the patients who did not develop an SPM, patients with an SPM were significantly older at first diagnosis, had a higher pathological stage and higher rates of biliary tract disease and thyroid disease. In addition, patients with an SPM were more likely to have received postoperative chemotherapy (28.43 vs. 12.16%, P<0.0001) and to be long‑term consumers of cigarettes and alcohol (25.00 vs. 8.95%, P<0.05). In addition, an increase in the number of regimens received but not in the number of courses of chemotherapy was associated with a reduction in the time interval to SPM development. Non‑small cell lung cancer (NSCLC) was the most common type of FPM (18.27%). In patients with NSCLC the occurrence of SPMs was relatively low (5.07%) and the SPM‑associated mortality rate was 2.30%. Breast cancer was the second common type of FPM (12.09%). Patients with breast cancer had a relatively high likelihood of developing an SPM (9.30%), for which family history of malignancy and postoperative chemotherapy were identified as potential risk factors. Patients with stomach cancer were the most vulnerable to SPM (17.95%) and patients with digestive tract cancer had the longest time interval between the FPM and SPM development. In addition, thyroid adenoma was identified as a potential risk factor for SCLC. The findings of the present study may provide valuable guidance for the short‑ and long‑term monitoring of FPM survivors.
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1 

Wu C, Li M, Meng H, Liu Y, Niu W, Zhou Y, Zhao R, Duan Y, Zeng Z, Li X, et al: Analysis of status and countermeasures of cancer incidence and mortality in china. Sci China Life Sci. 62:640–647. 2019. View Article : Google Scholar

2 

Zeng H, Chen W, Zheng R, Zhang S, Ji JS, Zou X, Xia C, Sun K, Yang Z, Li H, et al: Changing cancer survival in China during 2003-15: A pooled analysis of 17 population-based cancer registries. Lancet Glob Health. 6:e555–e567. 2018. View Article : Google Scholar : PubMed/NCBI

3 

Vogt A, Schmid S, Heinimann K, Frick H, Herrmann C, Cerny T and Omlin A: Multiple primary tumours: Challenges and approaches, a review. ESMO Open. 2:e0001722017. View Article : Google Scholar : PubMed/NCBI

4 

Donin N, Filson C, Drakaki A, Tan HJ, Castillo A, Kwan L, Litwin M and Chamie K: Risk of second primary malignancies among cancer survivors in the United States, 1992 through 2008. Cancer. 122:3075–3086. 2016. View Article : Google Scholar : PubMed/NCBI

5 

Rasmussen LA, Jensen H, Virgilsen LF, Falborg AZ, Møller H and Vedsted P: Healthcare utilisation in general practice and hospitals in the year preceding a diagnosis of cancer recurrence or second primary cancer: A population-based register study. BMC Health Serv Res. 19:9412019. View Article : Google Scholar : PubMed/NCBI

6 

Barclay ME, Lyratzopoulos G, Walter FM, Jefferies S, Peake MD and Rintoul RC: Incidence of second and higher order smoking-related primary cancers following lung cancer: A population-based cohort study. Thorax. 74:466–472. 2019. View Article : Google Scholar : PubMed/NCBI

7 

Jo JH, Cho IR, Jung JH, Lee HS, Chung MJ, Bang S, Park SW, Chung JB, Song SY and Park JY: Clinical characteristics of second primary pancreatic cancer. PLoS One. 12:e01797842017. View Article : Google Scholar : PubMed/NCBI

8 

Molina-Montes E, Pollán M, Payer T, Molina E, Dávila-Arias C and Sánchez MJ: Risk of second primary cancer among women with breast cancer: A population-based study in Granada (Spain). Gynecol Oncol. 130:340–345. 2013. View Article : Google Scholar

9 

Zheng X, Li X, Wang M, Shen J, Sisti G, He Z, Huang J, Li YM and Wu A: Second primary malignancies among cancer patients. Ann Transl Med. 8:6382020. View Article : Google Scholar : PubMed/NCBI

10 

Keegan THM, Bleyer A, Rosenberg AS, Li Q and Goldfarb M: Second Primary malignant neoplasms and survival in adolescent and young adult cancer survivors. JAMA Oncol. 3:1554–1557. 2017. View Article : Google Scholar

11 

Simard JL, Kircher SM, Didwania A and Goel MS: Screening for recurrence and secondary cancers. Med Clin North Am. 101:1167–1180. 2017. View Article : Google Scholar : PubMed/NCBI

12 

Liu Y, Cui P, Yang Z, Zhang P, Guo R and Shao G: Right lower lobectomy eight years after left pneumonectomy for a second primary lung cancer. J Cardiothorac Surg. 8:462013. View Article : Google Scholar : PubMed/NCBI

13 

Liu Y, Dong C and Chen L: The clinicopathological features of second primary cancer in patients with prior breast cancer. Medicine (Baltimore). 96:e66752017. View Article : Google Scholar : PubMed/NCBI

14 

Li F, Zhong WZ, Niu FY, Zhao N, Yang JJ, Yan HH and Wu YL: Multiple primary malignancies involving lung cancer. BMC Cancer. 15:6962015. View Article : Google Scholar : PubMed/NCBI

15 

Bian X, Wang K, Wang Q, Yang L, Xia J, Wu W and Li L: The impact of a prior malignancy on outcomes in gastric cancer patients. Cancer Med. 10:1457–1470. 2021. View Article : Google Scholar : PubMed/NCBI

16 

NCCN, . https://www.nccn.org/guidelines/category_1

17 

Toma-Dasu I, Wojcik A and Kjellsson Lindblom E: Risk of second cancer following radiotherapy. Phys Med. 42:211–212. 2017. View Article : Google Scholar : PubMed/NCBI

18 

Liang F, Zhang S, Xue H and Chen Q: Risk of second primary cancers in cancer patients treated with cisplatin: A systematic review and meta-analysis of randomized studies. BMC Cancer. 17:8712017. View Article : Google Scholar : PubMed/NCBI

19 

Wang Q, Shen Y, Ye B, Hu H, Fan C, Wang T, Zheng Y, Lv J, Ma Y and Xiang M: Gene expression differences between thyroid carcinoma, thyroid adenoma and normal thyroid tissue. Oncol Rep. 40:3359–3369. 2018.PubMed/NCBI

20 

Zhang H, Christensen CL, Dries R, Oser MG, Deng J, Diskin B, Li F, Pan Y, Zhang X, Yin Y, et al: CDK7 Inhibition potentiates genome instability triggering anti-tumor immunity in small cell lung cancer. Cancer Cell. 37:37–54.e9. 2020. View Article : Google Scholar

21 

Ireland AS, Micinski AM, Kastner DW, Guo B, Wait SJ, Spainhower KB, Conley CC, Chen OS, Guthrie MR, Soltero D, et al: MYC drives temporal evolution of small cell lung cancer subtypes by reprogramming neuroendocrine fate. Cancer Cell. 38:60–78. e122020. View Article : Google Scholar

22 

Na F, Pan X, Chen J, Chen X, Wang M, Chi P, You L, Zhang L, Zhong A, Zhao L, et al: KMT2C deficiency promotes small cell lung cancer metastasis through DNMT3A-mediated epigenetic reprogramming. Nat Cancer. 3:753–767. 2022. View Article : Google Scholar : PubMed/NCBI

23 

Dong P, Deng L, Xin X, Luo D, Liu Z, Sun H and Meng F: Risks of second primary malignancies among Chinese cancer survivors at a single center during 2002–2016. Transl Cancer Res. 7:257–267. 2018. View Article : Google Scholar

24 

Feng RM, Zong YN, Cao SM and Xu RH: Current cancer situation in China: Good or bad news from the 2018 Global Cancer Statistics? Cancer Commun (Lond). 39:222019. View Article : Google Scholar : PubMed/NCBI

25 

Wood ME, Vogel V, Ng A, Foxhall L, Goodwin P and Travis LB: Second malignant neoplasms: Assessment and strategies for risk reduction. J Clin Oncol. 30:3734–3745. 2012. View Article : Google Scholar

26 

Li Z, Wang K, Shi Y, Zhang X and Wen J: Incidence of second primary malignancy after breast cancer and related risk factors-Is breast-conserving surgery safe? A nested case-control study. Int J Cancer. 146:352–362. 2020. View Article : Google Scholar : PubMed/NCBI

27 

Liu Y, Zhang P, Zhang Y, Zheng L, Xu W, Hou D and Kang Z: Clinical characteristics and overall survival nomogram of second primary malignancies after prostate cancer, a SEER population-based study. Sci Rep. 11:12932021. View Article : Google Scholar : PubMed/NCBI

28 

Zang Y, Qi F, Cheng Y, Xia T, Xiao R, Li X and Yang N: Survival outcomes in prostate cancer patients with a prior cancer. Transl Androl Urol. 10:741–753. 2021. View Article : Google Scholar

29 

Bright CJ, Reulen RC, Winter DL, Stark DP, McCabe MG, Edgar AB, Frobisher C and Hawkins MM: Risk of subsequent primary neoplasms in survivors of adolescent and young adult cancer (Teenage and Young Adult Cancer Survivor Study): A population-based, cohort study. Lancet Oncol. 20:531–545. 2019. View Article : Google Scholar

30 

Mahmood S, Vu K, Tai P, Joseph K, Koul R, Dubey A and Yu E: Radiation-induced second malignancies. Anticancer Res. 35:2431–2434. 2015.PubMed/NCBI

31 

Berrington de Gonzalez A, Curtis RE, Kry SF, Gilbert E, Lamart S, Berg CD, Stovall M and Ron E: Proportion of second cancers attributable to radiotherapy treatment in adults: A cohort study in the US SEER Cancer Registries. Lancet Oncol. 12:353–360. 2011. View Article : Google Scholar

32 

Turcotte LM, Liu Q, Yasui Y, Henderson TO, Gibson TM, Leisenring W, Arnold MA, Howell RM, Green DM, Armstrong GT, et al: Chemotherapy and risk of subsequent malignant neoplasms in the Childhood Cancer Survivor Study Cohort. J Clin Oncol. 37:3310–3319. 2019. View Article : Google Scholar

33 

Morton LM, Swerdlow AJ, Schaapveld M, Ramadan S, Hodgson DC, Radford J and van Leeuwen FE: Current knowledge and future research directions in treatment-related second primary malignancies. EJC Suppl. 12:5–17. 2014. View Article : Google Scholar

34 

Adjei Boakye E, Buchanan P, Hinyard L, Osazuwa-Peters N, Simpson MC, Schootman M and Piccirillo JF: Trends in the risk and burden of second primary malignancy among survivors of smoking-related cancers in the United States. Int J Cancer. 145:143–153. 2019. View Article : Google Scholar : PubMed/NCBI

35 

Druesne-Pecollo N, Keita Y, Touvier M, Chan DS, Norat T, Hercberg S and Latino-Martel P: Alcohol drinking and second primary cancer risk in patients with upper aerodigestive tract cancers: A systematic review and meta-analysis of observational studies. Cancer Epidemiol Biomarkers Prev. 23:324–331. 2014. View Article : Google Scholar : PubMed/NCBI

36 

Park SM, Li T, Wu S, Li WQ, Qureshi AA, Stampfer M and Cho E: Risk of second primary cancer associated with pre-diagnostic smoking, alcohol, and obesity in women with keratinocyte carcinoma. Cancer Epidemiol. 47:106–113. 2017. View Article : Google Scholar

37 

Halamkova J, Kazda T, Pehalova L, Gonec R, Kozakova S, Bohovicova L, Slaby O, Demlova R, Svoboda M and Kiss I: The impact of diabetes mellitus on the second primary malignancies in colorectal cancer patients. Front Oncol. 10:5733942021. View Article : Google Scholar

38 

Park SM, Lim MK, Jung KW, Shin SA, Yoo KY, Yun YH and Huh BY: Prediagnosis smoking, obesity, insulin resistance, and second primary cancer risk in male cancer survivors: National Health Insurance Corporation Study. J Clin Oncol. 25:4835–4843. 2007. View Article : Google Scholar

39 

Khan SR, Chaker L, Ruiter R, Aerts JG, Hofman A, Dehghan A, Franco OH and Stricker BH: Thyroid function and cancer risk: The Rotterdam Study. J Clin Endocrinol Metab. 101:5030–5036. 2016. View Article : Google Scholar : PubMed/NCBI

40 

Hellevik AI, Asvold BO, Bjøro T, Romundstad PR, Nilsen TI and Vatten LJ: Thyroid function and cancer risk: A prospective population study. Cancer Epidemiol Biomarkers Prev. 18:570–574. 2009. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Geng F, Liu M, Chen J, Ge Y, Wei S, Li F, Yang C, Sun J, Gou L, Zhang J, Zhang J, et al: Clinical characteristics of second primary malignancies among first primary malignancy survivors: A single‑center study, 2005‑2020. Oncol Lett 25: 24, 2023.
APA
Geng, F., Liu, M., Chen, J., Ge, Y., Wei, S., Li, F. ... Zhang, J. (2023). Clinical characteristics of second primary malignancies among first primary malignancy survivors: A single‑center study, 2005‑2020. Oncology Letters, 25, 24. https://doi.org/10.3892/ol.2022.13610
MLA
Geng, F., Liu, M., Chen, J., Ge, Y., Wei, S., Li, F., Yang, C., Sun, J., Gou, L., Zhang, J., Tang, S., Wan, Y., Yang, J., Zhang, J."Clinical characteristics of second primary malignancies among first primary malignancy survivors: A single‑center study, 2005‑2020". Oncology Letters 25.1 (2023): 24.
Chicago
Geng, F., Liu, M., Chen, J., Ge, Y., Wei, S., Li, F., Yang, C., Sun, J., Gou, L., Zhang, J., Tang, S., Wan, Y., Yang, J., Zhang, J."Clinical characteristics of second primary malignancies among first primary malignancy survivors: A single‑center study, 2005‑2020". Oncology Letters 25, no. 1 (2023): 24. https://doi.org/10.3892/ol.2022.13610
Copy and paste a formatted citation
x
Spandidos Publications style
Geng F, Liu M, Chen J, Ge Y, Wei S, Li F, Yang C, Sun J, Gou L, Zhang J, Zhang J, et al: Clinical characteristics of second primary malignancies among first primary malignancy survivors: A single‑center study, 2005‑2020. Oncol Lett 25: 24, 2023.
APA
Geng, F., Liu, M., Chen, J., Ge, Y., Wei, S., Li, F. ... Zhang, J. (2023). Clinical characteristics of second primary malignancies among first primary malignancy survivors: A single‑center study, 2005‑2020. Oncology Letters, 25, 24. https://doi.org/10.3892/ol.2022.13610
MLA
Geng, F., Liu, M., Chen, J., Ge, Y., Wei, S., Li, F., Yang, C., Sun, J., Gou, L., Zhang, J., Tang, S., Wan, Y., Yang, J., Zhang, J."Clinical characteristics of second primary malignancies among first primary malignancy survivors: A single‑center study, 2005‑2020". Oncology Letters 25.1 (2023): 24.
Chicago
Geng, F., Liu, M., Chen, J., Ge, Y., Wei, S., Li, F., Yang, C., Sun, J., Gou, L., Zhang, J., Tang, S., Wan, Y., Yang, J., Zhang, J."Clinical characteristics of second primary malignancies among first primary malignancy survivors: A single‑center study, 2005‑2020". Oncology Letters 25, no. 1 (2023): 24. https://doi.org/10.3892/ol.2022.13610
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