Open Access

Biclonal lymphoplasmacytic lymphoma/Waldenström macroglobulinemia associated with POEMS syndrome: A case report and literature review

  • Authors:
    • Qiulan Wang
    • Qingbo Liu
    • Haonan Liang
    • Wenbin Gao
  • View Affiliations

  • Published online on: January 27, 2023     https://doi.org/10.3892/ol.2023.13683
  • Article Number: 97
  • Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Due to its unique clinical, immunological and molecular genetic characteristics, biclonal lymphoplasmacytic lymphoma/Waldenström macroglobulinemia (LPL/WM) with polyneuropathy, organomegaly, endocrinopathy, monoclonal protein and skin changes (POEMS) syndrome is extremely rare in clinical practice, and there is no standard treatment for patients afflicted with this condition. In the present case report, a rare case of double LPL/WM with POEMS syndrome is described. The patient, a 65‑year‑old male, exhibited significant renal impairment and polylymphadenopathy. The patient was treated with rituximab and his symptoms were resolved following two courses of treatment. A review of the literature was performed, comparing the present case with previous cases. It is hoped that this case report will enable clinicians to gain a better understanding of this disease.
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March-2023
Volume 25 Issue 3

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Copy and paste a formatted citation
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Spandidos Publications style
Wang Q, Liu Q, Liang H and Gao W: Biclonal lymphoplasmacytic lymphoma/Waldenström macroglobulinemia associated with POEMS syndrome: A case report and literature review. Oncol Lett 25: 97, 2023
APA
Wang, Q., Liu, Q., Liang, H., & Gao, W. (2023). Biclonal lymphoplasmacytic lymphoma/Waldenström macroglobulinemia associated with POEMS syndrome: A case report and literature review. Oncology Letters, 25, 97. https://doi.org/10.3892/ol.2023.13683
MLA
Wang, Q., Liu, Q., Liang, H., Gao, W."Biclonal lymphoplasmacytic lymphoma/Waldenström macroglobulinemia associated with POEMS syndrome: A case report and literature review". Oncology Letters 25.3 (2023): 97.
Chicago
Wang, Q., Liu, Q., Liang, H., Gao, W."Biclonal lymphoplasmacytic lymphoma/Waldenström macroglobulinemia associated with POEMS syndrome: A case report and literature review". Oncology Letters 25, no. 3 (2023): 97. https://doi.org/10.3892/ol.2023.13683