Open Access

Roles of TGF‑β signalling pathway‑related lncRNAs in cancer (Review)

  • Authors:
    • Zhizhong Hu
    • Yitong Liu
    • Meiqi Liu
    • Yang Zhang
    • Chengkun Wang
  • View Affiliations

  • Published online on: February 2, 2023     https://doi.org/10.3892/ol.2023.13693
  • Article Number: 107
  • Copyright: © Hu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Long non‑coding RNAs (lncRNAs) are a class of RNAs that are >200 nucleotides in length that do not have the ability to be translated into protein but are associated with numerous diseases, including cancer. The involvement of lncRNAs in the signalling of certain signalling pathways can promote tumour progression; these pathways include the transforming growth factor (TGF)‑β signalling pathway, which is related to tumour development. The expression of lncRNAs in various tumour tissues is specific, and their interaction with the TGF‑β signalling pathway indicates that they may serve as new tumour markers and therapeutic targets. The present review summarized the role of TGF‑β pathway‑associated lncRNAs in regulating tumorigenesis in different types of cancer and their effects on the TGF‑β signalling pathway.
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March-2023
Volume 25 Issue 3

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Hu Z, Liu Y, Liu M, Zhang Y and Wang C: Roles of TGF‑β signalling pathway‑related lncRNAs in cancer (Review). Oncol Lett 25: 107, 2023
APA
Hu, Z., Liu, Y., Liu, M., Zhang, Y., & Wang, C. (2023). Roles of TGF‑β signalling pathway‑related lncRNAs in cancer (Review). Oncology Letters, 25, 107. https://doi.org/10.3892/ol.2023.13693
MLA
Hu, Z., Liu, Y., Liu, M., Zhang, Y., Wang, C."Roles of TGF‑β signalling pathway‑related lncRNAs in cancer (Review)". Oncology Letters 25.3 (2023): 107.
Chicago
Hu, Z., Liu, Y., Liu, M., Zhang, Y., Wang, C."Roles of TGF‑β signalling pathway‑related lncRNAs in cancer (Review)". Oncology Letters 25, no. 3 (2023): 107. https://doi.org/10.3892/ol.2023.13693