Obstruction of the biliary tract as a rare presentation of acute myeloid leukemia: A case report

Tu,Shengke; Li,Min; Fan,Hongjie; Shi,Ziwei; Li,Xiaolan; Song,Kui

doi:10.3892/ol.2023.13886

July-2023 Volume 26 Issue 1

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July-2023 Volume 26 Issue 1

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Case Report Open Access

Obstruction of the biliary tract as a rare presentation of acute myeloid leukemia: A case report

Authors:
- Shengke Tu
- Min Li
- Hongjie Fan
- Ziwei Shi
- Xiaolan Li
- Kui Song
View Affiliations / Copyright

Affiliations: Department of Hematology, The First Affiliated Hospital of Jishou University, Jishou, Hunan 416000, P.R. China, Department of Pharmacy, The First Affiliated Hospital of Jishou University, Jishou, Hunan 416000, P.R. China, College of Biological Resources and Environmental Sciences, Jishou University, Jishou, Hunan 416000, P.R. China, Department of Hematology, The First Affiliated Hospital of Jishou University, Jishou, Hunan 416000, P.R. China

Copyright: © Tu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Article Number: 300
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Published online on: May 26, 2023

https://doi.org/10.3892/ol.2023.13886
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Abstract

To investigate the clinical characteristics of acute myeloid leukemia (AML) with biliary obstruction as the first manifestation and explore the treatment options. A retrospective analysis was performed on a case of AML with biliary obstruction as the first manifestation admitted to the First Affiliated Hospital of Jishou University (Jishou, China). The relevant laboratory examination, imaging, pathological results and treatment strategies were analyzed. The patient was a 44‑year‑old male with an initial manifestation of biliary obstruction. Combined with the results of laboratory tests and bone marrow aspiration, the patient was diagnosed with AML and was treated with an IA regimen (idarubicin 8 mg d1‑3, cytarabine 0.2 d1‑5). After 2 courses of treatment, complete response was achieved, the liver function returned to normal and the biliary obstruction disappeared. The initial symptoms of AML are varied, and always combine with multi‑system organ damage. Early diagnosis and active treatment of primary diseases are the keys to improving the prognosis of these patients.

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