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Prostate biopsy approach and complication rates

  • Authors:
    • Kinga Mate
    • Saleh Nedjim
    • Simon Bellucci
    • Cesar Boucault
    • Nael Ghaffar
    • Tracy Constantini
    • Fanni Marvanykovi
    • Pierre-Gilles Vestris
    • Yvanne Sadreux
    • Melanie Laguerre
    • Gautier Stempfer
    • Pascal Blanchet
    • Buzogany Istvan
    • Laurent Brureau
  • View Affiliations / Copyright

    Affiliations: Department of Urology, Péterfy Sándor Utcai Hospital‑Clinic and Trauma Centre, Budapest 1076, Hungary, Department of Urology, Ibn Rochd University Hospital, Casablanca 50169, Morocco, Department of Urology, Free University of Brussels, 1050 Brussels, Belgium, Department of Urology, University Hospital of Pointe à Pitre, Les Abymes 97159, Guadeloupe, France
    Copyright: © Mate et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 375
    |
    Published online on: July 17, 2023
       https://doi.org/10.3892/ol.2023.13959
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Abstract

Prostate biopsy is the gold standard to confirm prostate cancer. In addition to standard 12‑core biopsies, magnetic resonance imaging (MRI)‑guided prostate biopsies have recently been introduced to improve the detection of clinically significant prostate cancer. The present study aimed to compare the complications after standard transrectal ultrasound‑guided and standard plus targeted (MRI‑guided) prostate biopsies, to study the impact of the number of biopsy cores on complication rates, and to compare complication rates after transrectal ultrasound‑guided prostate biopsies with those following transperineal prostate biopsies from the literature. A prospective study was performed, which included 135 patients who underwent transrectal ultrasound‑guided prostate biopsies between April 1 and June 30, 2022, at the Urology Department of the University Hospital of Pointe à Pitre (Pointe à Pitre, Guadeloupe). A total of 51 patients were excluded because of missing information concerning their post‑biopsy surveillance. The median age at the time of biopsy was 69 years, median prostate‑specific antigen value was 8.9 ng/ml, median prostate volume was 57.5 ml, and median number of cores was 15. A total of 35 of the 84 included patients (41.7%) had a standard biopsy only and 49 (58.3%) had targeted (MRI‑guided) plus standard biopsies. A total of 53 patients (63.1%) experienced early side effects, whereas only 24 patients (28.6%) experienced late side effects. Three patients (3.6%) required hospitalization for post‑biopsy complications. Early side effects, especially hematuria and hematospermia, occurred significantly more frequently in the targeted plus standard group, with more cores taken, with no significant difference concerning late side effects or infectious complications between the standard and standard plus targeted groups. The admission rate for sepsis after transperineal biopsy has been reported to vary between 0 and 1%, whereas the present study had an admission rate of 2.29% using the transrectal approach. Further studies are required to analyze the complications requiring hospitalization after transrectal and transperineal biopsies.
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Copy and paste a formatted citation
Spandidos Publications style
Mate K, Nedjim S, Bellucci S, Boucault C, Ghaffar N, Constantini T, Marvanykovi F, Vestris P, Sadreux Y, Laguerre M, Laguerre M, et al: Prostate biopsy approach and complication rates. Oncol Lett 26: 375, 2023.
APA
Mate, K., Nedjim, S., Bellucci, S., Boucault, C., Ghaffar, N., Constantini, T. ... Brureau, L. (2023). Prostate biopsy approach and complication rates. Oncology Letters, 26, 375. https://doi.org/10.3892/ol.2023.13959
MLA
Mate, K., Nedjim, S., Bellucci, S., Boucault, C., Ghaffar, N., Constantini, T., Marvanykovi, F., Vestris, P., Sadreux, Y., Laguerre, M., Stempfer, G., Blanchet, P., Istvan, B., Brureau, L."Prostate biopsy approach and complication rates". Oncology Letters 26.3 (2023): 375.
Chicago
Mate, K., Nedjim, S., Bellucci, S., Boucault, C., Ghaffar, N., Constantini, T., Marvanykovi, F., Vestris, P., Sadreux, Y., Laguerre, M., Stempfer, G., Blanchet, P., Istvan, B., Brureau, L."Prostate biopsy approach and complication rates". Oncology Letters 26, no. 3 (2023): 375. https://doi.org/10.3892/ol.2023.13959
Copy and paste a formatted citation
x
Spandidos Publications style
Mate K, Nedjim S, Bellucci S, Boucault C, Ghaffar N, Constantini T, Marvanykovi F, Vestris P, Sadreux Y, Laguerre M, Laguerre M, et al: Prostate biopsy approach and complication rates. Oncol Lett 26: 375, 2023.
APA
Mate, K., Nedjim, S., Bellucci, S., Boucault, C., Ghaffar, N., Constantini, T. ... Brureau, L. (2023). Prostate biopsy approach and complication rates. Oncology Letters, 26, 375. https://doi.org/10.3892/ol.2023.13959
MLA
Mate, K., Nedjim, S., Bellucci, S., Boucault, C., Ghaffar, N., Constantini, T., Marvanykovi, F., Vestris, P., Sadreux, Y., Laguerre, M., Stempfer, G., Blanchet, P., Istvan, B., Brureau, L."Prostate biopsy approach and complication rates". Oncology Letters 26.3 (2023): 375.
Chicago
Mate, K., Nedjim, S., Bellucci, S., Boucault, C., Ghaffar, N., Constantini, T., Marvanykovi, F., Vestris, P., Sadreux, Y., Laguerre, M., Stempfer, G., Blanchet, P., Istvan, B., Brureau, L."Prostate biopsy approach and complication rates". Oncology Letters 26, no. 3 (2023): 375. https://doi.org/10.3892/ol.2023.13959
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