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September-2023 Volume 26 Issue 3

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Case Report Open Access

Radiotherapy in Philadelphia chromosome‑positive acute lymphoblastic leukemia with pericardial invasion after transplantation: A case report

  • Authors:
    • Jing Yuan
    • Yong Zhang
    • Hebing Zhou
    • Sen Wang
    • Qiteng Liu
    • Yuyan Gao

  • View Affiliations / Copyright

    Affiliations: Department of Radiotherapy, Beijing LuHe Hospital, Capital Medical University, Beijing 101100, P.R. China, Department of Hematology, Beijing LuHe Hospital, Capital Medical University, Beijing 101100, P.R. China, Department of Neurosurgery, Beijing LuHe Hospital, Capital Medical University, Beijing 101100, P.R. China
    Copyright: © Yuan et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 415
    |
    Published online on: August 8, 2023
       https://doi.org/10.3892/ol.2023.14001
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Abstract

The present report describes a case of Philadelphia chromosome‑positive acute lymphoblastic leukemia (Ph+ALL) with pericardial invasion following bone marrow transplantation. The patient exhibited recurrent pericardial effusion accompanied by wheezing symptoms. Despite undergoing multiple pericardial punctures and drainage procedures, pericardial injections, and systemic treatment, the patient continued to experience recurrent pericardial effusion. Ultimately, the patient underwent whole‑heart radiotherapy, resulting in complete resolution of the pericardial effusion. After a follow‑up period of 10 months, the pericardial effusion remained well‑controlled, and there were no significant impairments in cardiac function. In conclusion, radiotherapy may be considered as a viable treatment option for refractory leukemia cases presenting with pericardial effusion.
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Copy and paste a formatted citation
Spandidos Publications style
Yuan J, Zhang Y, Zhou H, Wang S, Liu Q and Gao Y: Radiotherapy in Philadelphia chromosome‑positive acute lymphoblastic leukemia with pericardial invasion after transplantation: A case report. Oncol Lett 26: 415, 2023.
APA
Yuan, J., Zhang, Y., Zhou, H., Wang, S., Liu, Q., & Gao, Y. (2023). Radiotherapy in Philadelphia chromosome‑positive acute lymphoblastic leukemia with pericardial invasion after transplantation: A case report. Oncology Letters, 26, 415. https://doi.org/10.3892/ol.2023.14001
MLA
Yuan, J., Zhang, Y., Zhou, H., Wang, S., Liu, Q., Gao, Y."Radiotherapy in Philadelphia chromosome‑positive acute lymphoblastic leukemia with pericardial invasion after transplantation: A case report". Oncology Letters 26.3 (2023): 415.
Chicago
Yuan, J., Zhang, Y., Zhou, H., Wang, S., Liu, Q., Gao, Y."Radiotherapy in Philadelphia chromosome‑positive acute lymphoblastic leukemia with pericardial invasion after transplantation: A case report". Oncology Letters 26, no. 3 (2023): 415. https://doi.org/10.3892/ol.2023.14001
Copy and paste a formatted citation
x
Spandidos Publications style
Yuan J, Zhang Y, Zhou H, Wang S, Liu Q and Gao Y: Radiotherapy in Philadelphia chromosome‑positive acute lymphoblastic leukemia with pericardial invasion after transplantation: A case report. Oncol Lett 26: 415, 2023.
APA
Yuan, J., Zhang, Y., Zhou, H., Wang, S., Liu, Q., & Gao, Y. (2023). Radiotherapy in Philadelphia chromosome‑positive acute lymphoblastic leukemia with pericardial invasion after transplantation: A case report. Oncology Letters, 26, 415. https://doi.org/10.3892/ol.2023.14001
MLA
Yuan, J., Zhang, Y., Zhou, H., Wang, S., Liu, Q., Gao, Y."Radiotherapy in Philadelphia chromosome‑positive acute lymphoblastic leukemia with pericardial invasion after transplantation: A case report". Oncology Letters 26.3 (2023): 415.
Chicago
Yuan, J., Zhang, Y., Zhou, H., Wang, S., Liu, Q., Gao, Y."Radiotherapy in Philadelphia chromosome‑positive acute lymphoblastic leukemia with pericardial invasion after transplantation: A case report". Oncology Letters 26, no. 3 (2023): 415. https://doi.org/10.3892/ol.2023.14001
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