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Case Report Open Access

Mixed medullary‑follicular thyroid carcinoma: A case report and literature review

  • Authors:
    • Yonghui Wang
    • Dandan Yin
    • Guifang Ren
    • Zhengjiang Wang
    • Fanhua Kong
  • View Affiliations / Copyright

    Affiliations: Department of Thyroid and Breast Surgery, Weifang People's Hospital, Weifang, Shandong 261041, P.R. China, Department of Pathology, Weifang People's Hospital, Weifang, Shandong 261041, P.R. China, Department of Hospital Office, Weifang People's Hospital, Weifang, Shandong 261041, P.R. China
    Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 429
    |
    Published online on: August 18, 2023
       https://doi.org/10.3892/ol.2023.14015
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Abstract

Papillary thyroid cancer (PTC) and medullary thyroid cancer (MTC) originate from follicular and neuroendocrine parafollicular C cells, respectively. PTC and MTC simultaneously exist in tumors containing both MTC and PTC features in a rare condition known as mixed medullary‑follicular thyroid carcinoma (MMFTC). In the present study, a 60‑year‑old female presented with a small mass on the left side of the neck. Ultrasonography indicated a hyperechoic nodule measuring ~11.9x9.7 mm2 in the left lobe of the thyroid gland. The preoperative calcitonin serum value was elevated and total thyroidectomy and bilateral central compartment lymph node dissection was performed. Histological and immunohistochemical analysis of the tumor demonstrated MMFTC. No metastasis was observed in lymph nodes isolated from the bilateral central compartment. Given the rarity of MMFTC, enhancing understanding and management of such tumors is crucial.
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Copy and paste a formatted citation
Spandidos Publications style
Wang Y, Yin D, Ren G, Wang Z and Kong F: Mixed medullary‑follicular thyroid carcinoma: A case report and literature review. Oncol Lett 26: 429, 2023.
APA
Wang, Y., Yin, D., Ren, G., Wang, Z., & Kong, F. (2023). Mixed medullary‑follicular thyroid carcinoma: A case report and literature review. Oncology Letters, 26, 429. https://doi.org/10.3892/ol.2023.14015
MLA
Wang, Y., Yin, D., Ren, G., Wang, Z., Kong, F."Mixed medullary‑follicular thyroid carcinoma: A case report and literature review". Oncology Letters 26.4 (2023): 429.
Chicago
Wang, Y., Yin, D., Ren, G., Wang, Z., Kong, F."Mixed medullary‑follicular thyroid carcinoma: A case report and literature review". Oncology Letters 26, no. 4 (2023): 429. https://doi.org/10.3892/ol.2023.14015
Copy and paste a formatted citation
x
Spandidos Publications style
Wang Y, Yin D, Ren G, Wang Z and Kong F: Mixed medullary‑follicular thyroid carcinoma: A case report and literature review. Oncol Lett 26: 429, 2023.
APA
Wang, Y., Yin, D., Ren, G., Wang, Z., & Kong, F. (2023). Mixed medullary‑follicular thyroid carcinoma: A case report and literature review. Oncology Letters, 26, 429. https://doi.org/10.3892/ol.2023.14015
MLA
Wang, Y., Yin, D., Ren, G., Wang, Z., Kong, F."Mixed medullary‑follicular thyroid carcinoma: A case report and literature review". Oncology Letters 26.4 (2023): 429.
Chicago
Wang, Y., Yin, D., Ren, G., Wang, Z., Kong, F."Mixed medullary‑follicular thyroid carcinoma: A case report and literature review". Oncology Letters 26, no. 4 (2023): 429. https://doi.org/10.3892/ol.2023.14015
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