Rare presentation of esophageal squamous cell carcinoma with rectal metastasis: A case report

Kang,Mei; Zhu,Liyang; Yang,Mingwei; Zhang,Yin; Wang,Shiyu; Wang,Yichun

doi:10.3892/ol.2023.14097

Rare presentation of esophageal squamous cell carcinoma with rectal metastasis: A case report

Authors:
- Mei Kang
- Liyang Zhu
- Mingwei Yang
- Yin Zhang
- Shiyu Wang
- Yichun Wang
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Affiliations: Department of Radiation Oncology, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China, Department of Pathology, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China, Department of Radiology, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China
Published online on: October 12, 2023 https://doi.org/10.3892/ol.2023.14097
Article Number: 510

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Abstract

Esophageal cancer is usually diagnosed at an advanced stage, resulting in poor survival. The common sites of distant metastasis include lung, liver and bones. The present study reports a rare case of esophageal squamous cell carcinoma (SCC) with rectal metastasis. A 65‑year‑old man was diagnosed with middle thoracic esophageal SCC with multiple lymph node metastasis. The patient achieved good response after chemoradiotherapy and adjuvant chemotherapy. During following up, the computed tomography and magnetic resonance scans showed a mass in front of the rectum with intact mucosa. Biopsies were performed and histopathological findings showed SCC, consistent with metastasis from primary esophageal SCC. The patient subsequently received palliative chemoradiotherapy to the rectal tumour and survived for 5 months. To the best of our knowledge, the present case is the first report of metastatic rectal SCC from the esophagus. It is important to take a biopsy of this unexpected lesion for histological analysis, which can help to discriminate metastatic from primary cancer. The goal of treatment is palliative therapy to improve quality of life and survival for this metastatic disease.

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