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Case Report Open Access

Renal cell carcinoma associated with Xp11.2 translocation/transcription factor E3 gene fusion: A case report and literature review

  • Authors:
    • Denghao Yang
    • Wen Tang
    • Mingwen Liu
    • Zhifei Xie
    • Fei Shi
    • Zeju Zhao
    • Xiaorong Yang
    • Tao Wu
  • View Affiliations / Copyright

    Affiliations: Department of Urology, The Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563000, P.R. China, Department of Urology, People's Hospital of Honghuagang District, Zunyi, Guizhou 563000, P.R. China, Department of Pathology, The Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563000, P.R. China
    Copyright: © Yang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 29
    |
    Published online on: November 21, 2023
       https://doi.org/10.3892/ol.2023.14162
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Abstract

Renal cell carcinoma (RCC) associated with Xp11.2 translocation/transcription factor E3 (TFE3) gene fusion is a rare subtype of RCC. A 31‑year‑old male patient was admitted to The Affiliated Hospital of Zunyi Medical University (Zunyi, China) with a solid mass in the left kidney during a routine health examination. After ruling out surgical contraindications, the patient underwent a laparoscopic left partial nephrectomy under general anesthesia. Postoperative pathology and fluorescence in situ hybridization (FISH) identified Xp11.2 translocation RCC. There was no tumor recurrence or metastasis during the 1‑year follow‑up. Xp11.2 translocation RCC is unusual, its clinical and imaging findings are not specific, and the diagnosis depends on TFE3‑immunohistochemical assay and FISH analysis. Surgical resection is the first choice of treatment and its prognosis is worse than that of clear cell RCC, thus regular follow‑ups are necessary.
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Copy and paste a formatted citation
Spandidos Publications style
Yang D, Tang W, Liu M, Xie Z, Shi F, Zhao Z, Yang X and Wu T: Renal cell carcinoma associated with Xp11.2 translocation/transcription factor E3 gene fusion: A case report and literature review. Oncol Lett 27: 29, 2024.
APA
Yang, D., Tang, W., Liu, M., Xie, Z., Shi, F., Zhao, Z. ... Wu, T. (2024). Renal cell carcinoma associated with Xp11.2 translocation/transcription factor E3 gene fusion: A case report and literature review. Oncology Letters, 27, 29. https://doi.org/10.3892/ol.2023.14162
MLA
Yang, D., Tang, W., Liu, M., Xie, Z., Shi, F., Zhao, Z., Yang, X., Wu, T."Renal cell carcinoma associated with Xp11.2 translocation/transcription factor E3 gene fusion: A case report and literature review". Oncology Letters 27.1 (2024): 29.
Chicago
Yang, D., Tang, W., Liu, M., Xie, Z., Shi, F., Zhao, Z., Yang, X., Wu, T."Renal cell carcinoma associated with Xp11.2 translocation/transcription factor E3 gene fusion: A case report and literature review". Oncology Letters 27, no. 1 (2024): 29. https://doi.org/10.3892/ol.2023.14162
Copy and paste a formatted citation
x
Spandidos Publications style
Yang D, Tang W, Liu M, Xie Z, Shi F, Zhao Z, Yang X and Wu T: Renal cell carcinoma associated with Xp11.2 translocation/transcription factor E3 gene fusion: A case report and literature review. Oncol Lett 27: 29, 2024.
APA
Yang, D., Tang, W., Liu, M., Xie, Z., Shi, F., Zhao, Z. ... Wu, T. (2024). Renal cell carcinoma associated with Xp11.2 translocation/transcription factor E3 gene fusion: A case report and literature review. Oncology Letters, 27, 29. https://doi.org/10.3892/ol.2023.14162
MLA
Yang, D., Tang, W., Liu, M., Xie, Z., Shi, F., Zhao, Z., Yang, X., Wu, T."Renal cell carcinoma associated with Xp11.2 translocation/transcription factor E3 gene fusion: A case report and literature review". Oncology Letters 27.1 (2024): 29.
Chicago
Yang, D., Tang, W., Liu, M., Xie, Z., Shi, F., Zhao, Z., Yang, X., Wu, T."Renal cell carcinoma associated with Xp11.2 translocation/transcription factor E3 gene fusion: A case report and literature review". Oncology Letters 27, no. 1 (2024): 29. https://doi.org/10.3892/ol.2023.14162
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