Role of interleukin‑32 in cancer progression (Review)

  • Authors:
    • Danyang Meng
    • Hang Dong
    • Chennan Wang
    • Rongjia Zang
    • Jianjie Wang
  • View Affiliations

  • Published online on: December 12, 2023     https://doi.org/10.3892/ol.2023.14187
  • Article Number: 54
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Abstract

Interleukin (IL)‑32 is induced by pro‑inflammatory cytokines and promotes the release of inflammatory cytokines. Therefore, it can promote inflammatory responses. The present review article summarized the role of the receptors required for IL‑32 action, the biological function of IL‑32 and its mechanism of action in tumors. Moreover, it assessed the significance of aberrant IL‑32 expression in associated diseases and analyzed the effects of IL‑32 on four key types of cancer: Colorectal, gastric, breast and lung. However, the mechanism of action of IL‑32 needs to be further demonstrated by assessing the role of this cytokine in cancer to elucidate novel and reliable targets for future cancer treatments.
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February-2024
Volume 27 Issue 2

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Meng D, Dong H, Wang C, Zang R and Wang J: Role of interleukin‑32 in cancer progression (Review). Oncol Lett 27: 54, 2024
APA
Meng, D., Dong, H., Wang, C., Zang, R., & Wang, J. (2024). Role of interleukin‑32 in cancer progression (Review). Oncology Letters, 27, 54. https://doi.org/10.3892/ol.2023.14187
MLA
Meng, D., Dong, H., Wang, C., Zang, R., Wang, J."Role of interleukin‑32 in cancer progression (Review)". Oncology Letters 27.2 (2024): 54.
Chicago
Meng, D., Dong, H., Wang, C., Zang, R., Wang, J."Role of interleukin‑32 in cancer progression (Review)". Oncology Letters 27, no. 2 (2024): 54. https://doi.org/10.3892/ol.2023.14187