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Dairy consumption and liver cancer risk: A meta‑analysis of observational studies

  • Authors:
    • Jiaying Dai
    • Tong Yin
    • Liying Cao
  • View Affiliations / Copyright

    Affiliations: Department of Hepatobiliary Surgery, KaiLuan General Hospital, North China University of Science and Technology, Tangshan, Hebei 063000, P.R. China, Department of Ultrasound, North China University of Science and Technology Affiliated Hospital, North China University of Science and Technology, Tangshan, Hebei 063000, P.R. China
    Copyright: © Dai et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY_NC 4.0].
  • Article Number: 108
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    Published online on: January 18, 2024
       https://doi.org/10.3892/ol.2024.14240
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Abstract

The connection between the consumption of dairy products and the risk of developing primary liver cancer (PLC) remains unclear. The present study performed a comprehensive meta‑analysis with the aim of providing evidence for any connection between the risk of developing PLC and the consumption of dairy products. For this purpose, eligible studies were screened from the PubMed, Cochrane Library and Embase databases before December 2022. A total of 10 cohort studies and 8 case‑control studies were included, making a total of 18 studies with 6,562,714 participants and 7,970 PLC cases. The relative risks (RRs) for milk and yogurt were 1.38 [95% confidence interval (CI), 1.07‑1.77] and 0.49 (95% CI, 0.27‑0.91), which revealed a positive and negative association, respectively, with the risk of developing PLC. There was no association between total dairy (RR, 1.04; 95% CI, 0.84‑1.30) or cheese and curd (RR, 1.05; 95% CI, 0.87‑1.27) consumption and the risk of developing PLC. On the whole, the findings of the present study demonstrated that high milk consumption was associated with a higher risk of developing PLC, while by contrast, yogurt consumption was associated with a lower risk of developing PLC. Consequently, further studies are required to further examine this association.
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Copy and paste a formatted citation
Spandidos Publications style
Dai J, Yin T and Cao L: Dairy consumption and liver cancer risk: A meta‑analysis of observational studies. Oncol Lett 27: 108, 2024.
APA
Dai, J., Yin, T., & Cao, L. (2024). Dairy consumption and liver cancer risk: A meta‑analysis of observational studies. Oncology Letters, 27, 108. https://doi.org/10.3892/ol.2024.14240
MLA
Dai, J., Yin, T., Cao, L."Dairy consumption and liver cancer risk: A meta‑analysis of observational studies". Oncology Letters 27.3 (2024): 108.
Chicago
Dai, J., Yin, T., Cao, L."Dairy consumption and liver cancer risk: A meta‑analysis of observational studies". Oncology Letters 27, no. 3 (2024): 108. https://doi.org/10.3892/ol.2024.14240
Copy and paste a formatted citation
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Spandidos Publications style
Dai J, Yin T and Cao L: Dairy consumption and liver cancer risk: A meta‑analysis of observational studies. Oncol Lett 27: 108, 2024.
APA
Dai, J., Yin, T., & Cao, L. (2024). Dairy consumption and liver cancer risk: A meta‑analysis of observational studies. Oncology Letters, 27, 108. https://doi.org/10.3892/ol.2024.14240
MLA
Dai, J., Yin, T., Cao, L."Dairy consumption and liver cancer risk: A meta‑analysis of observational studies". Oncology Letters 27.3 (2024): 108.
Chicago
Dai, J., Yin, T., Cao, L."Dairy consumption and liver cancer risk: A meta‑analysis of observational studies". Oncology Letters 27, no. 3 (2024): 108. https://doi.org/10.3892/ol.2024.14240
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